Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Xihao Hu"'
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 102969- (2024)
Summary: The expeditious identification and comprehensive analysis of clonal families from extensive B cell receptor (BCR) repertoire sequencing data are imperative for elucidating the intricacies of B cell immune responses. Here, we introduce a comp
Externí odkaz:
https://doaj.org/article/1be304c8261e47518dc4ceb38d0e754a
Autor:
Bin Xie, Yulong Li, Karim A Benhadji, X Shirley Liu, Xiangyang Wu, Hailing Liu, Xi Xiao, Huizhu Liu, Qingyang Ding, Caibin Sheng, Rongbin Zheng, Quan Yu, Xihao Hu, Tengfei Xiao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/7c9ee5c6b095457dbff310cea9044fb5
Publikováno v:
Cell Reports: Methods, Vol 3, Iss 10, Pp 100601- (2023)
Summary: Advances in high-throughput sequencing technologies have facilitated the large-scale characterization of B cell receptor (BCR) repertoires. However, the vast amount and high diversity of the BCR sequences pose challenges for efficient and bi
Externí odkaz:
https://doaj.org/article/5615d258e44b4fdeac9ab41ce2b4c951
Autor:
Shengqing Stan Gu, Xiaoqing Wang, Xihao Hu, Peng Jiang, Ziyi Li, Nicole Traugh, Xia Bu, Qin Tang, Chenfei Wang, Zexian Zeng, Jingxin Fu, Cliff Meyer, Yi Zhang, Paloma Cejas, Klothilda Lim, Jin Wang, Wubing Zhang, Collin Tokheim, Avinash Das Sahu, Xiaofang Xing, Benjamin Kroger, Zhangyi Ouyang, Henry Long, Gordon J. Freeman, Myles Brown, X. Shirley Liu
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-28 (2020)
Abstract Background Immune checkpoint blockade (ICB) therapy has improved patient survival in a variety of cancers, but only a minority of cancer patients respond. Multiple studies have sought to identify general biomarkers of ICB response, but eluci
Externí odkaz:
https://doaj.org/article/b3244746e20a48e2bb9e322dbec655a3
Autor:
Jian Zhang, Xihao Hu, Jin Wang, Avinash Das Sahu, David Cohen, Li Song, Zhangyi Ouyang, Jingyu Fan, Binbin Wang, Jingxin Fu, Shengqing Gu, Moshe Sade-Feldman, Nir Hacohen, Wuju Li, Xiaomin Ying, Bo Li, X. Shirley Liu
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-11 (2019)
Abstract Background Acute myeloid leukemia (AML), caused by the abnormal proliferation of immature myeloid cells in the blood or bone marrow, is one of the most common hematologic malignancies. Currently, the interactions between malignant myeloid ce
Externí odkaz:
https://doaj.org/article/451f73e2e69f431db98923ca1e3a0825
Autor:
Francesco Nannini, Lenart Senicar, Farhaan Parekh, Khai J. Kong, Alexander Kinna, Reyisa Bughda, James Sillibourne, Xihao Hu, Biao Ma, Yuchen Bai, Mathieu Ferrari, Martin A. Pule, Shimobi C. Onuoha
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Phage display technology in combination with next-generation sequencing (NGS) currently is a state-of-the-art method for the enrichment and isolation of monoclonal antibodies from diverse libraries. However, the current NGS methods employed for seque
Externí odkaz:
https://doaj.org/article/0fb7f6dbbb2349a594c6d571d3da7749
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195410 (2018)
Identifying essential proteins is very important for understanding the minimal requirements of cellular life and finding human disease genes as well as potential drug targets. Experimental methods for identifying essential proteins are often costly,
Externí odkaz:
https://doaj.org/article/748d540819e340dd8307f7b50d244945
Autor:
Kai Lian, Guangyan Chen, Xiaoqiang Wang, Wenna Zhang, Xihao Hu, Hui Wang, Yusen Li, Dongmei Xi, Ying Wang
Publikováno v:
RSC Advances. 13:1587-1593
A rapid, simple, and sensitive fluorescent detection method for brown spot of tobacco is established by lambda exonuclease-induced Mg2+-dependent DNAzyme amplification.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::694a14c3f3f011920b30c29329d1a15f
https://doi.org/10.1039/d2ra05616j
https://doi.org/10.1039/d2ra05616j
Autor:
X. Shirley Liu, Bo Li, Ming Tang, Heng Li, Kenneth J. Livak, Xihao Hu, Gali Bai, Jennifer Altreuter, Yang Cao, David Cohen, Zhangyi Ouyang, Li Song
Supplementary Data from Comprehensive Characterizations of Immune Receptor Repertoire in Tumors and Cancer Immunotherapy Studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ed4d8d70981ab3df91d3349363625f
https://doi.org/10.1158/2326-6066.22544673
https://doi.org/10.1158/2326-6066.22544673
Autor:
X. Shirley Liu, Bo Li, Ming Tang, Heng Li, Kenneth J. Livak, Xihao Hu, Gali Bai, Jennifer Altreuter, Yang Cao, David Cohen, Zhangyi Ouyang, Li Song
We applied our computational algorithm TRUST4 to assemble immune receptor (T-cell receptor/B-cell receptor) repertoires from approximately 12,000 RNA sequencing samples from The Cancer Genome Atlas and seven immunotherapy studies. From over 35 millio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7189dcc59f29f5bf1a9eba2715dc674f
https://doi.org/10.1158/2326-6066.c.6550716.v1
https://doi.org/10.1158/2326-6066.c.6550716.v1