Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Xihan Wu"'
Publikováno v:
Polymers, Vol 15, Iss 9, p 2113 (2023)
Recently, polymer nanocomposites have attracted great interest due to their remarkable characteristics of high performance and enabling production of low-cost devices. This article explores the reflective index sensing application of the polymer nano
Externí odkaz:
https://doaj.org/article/147f4d43067f41ce8935f88fba3968d7
Publikováno v:
Polymers, Vol 14, Iss 23, p 5234 (2022)
Taking advantage of the large thermo-optical coefficient of polymer materials, a hybrid-integrated thermo-optic switch was designed and simulated. It is also compatible with the existing silica-based planar light-wave circuit (PLC) platform. To furth
Externí odkaz:
https://doaj.org/article/0b4fdecab9e04fa0bb5dd907a894ccae
Publikováno v:
Polymers, Vol 14, Iss 19, p 3967 (2022)
The slot structure has great advantages in improving the sensitivity of integrated waveguide optical sensors and reducing the detection limit. We propose a polymer Mach–Zehnder interferometer (MZI) optical sensor based on the slot structure and ado
Externí odkaz:
https://doaj.org/article/64aceda839d54ad78968854eaad7c0b4
Autor:
Wang Liu, Yu Lu, Xiaoping Chai, Xiao Liu, Tong Zhu, Xihan Wu, Yanfen Fang, Xuan Liu, Xiongwen Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 35, Iss 1, Pp 1-15 (2016)
Abstract Background Overexpression of Aurora A and B has been reported in a wide range of tumor types, including gastric cancer. Anti-angiogenesis has been considered as an important therapeutic modality in advanced gastric cancer. Here we identified
Externí odkaz:
https://doaj.org/article/39e8d7fd23f743bf9e03d6e0d4e3fa35
Autor:
Chao Zhang, Xihan Wu, Meifang Zhang, Liangcheng Zhu, Rong Zhao, Danqing Xu, Zhaohu Lin, Chungen Liang, Taiping Chen, Li Chen, Yi Ren, Joe Zhang, Ning Qin, Xiongwen Zhang
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65264 (2013)
Protein kinases play important roles in tumor development and progression. Lots of kinase inhibitors have entered into market and show promising clinical benefits. Here we report the discovery of a novel small molecule, well-tolerated, orally active
Externí odkaz:
https://doaj.org/article/fa3ab6b478f64dfb8c299042e7dc6104
Autor:
Xihan Wu, Xuan Liu, Wang Liu, Yu Lu, Xiaoping Chai, Yanfen Fang, Xiao Liu, Xiongwen Zhang, Tong Zhu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 35, Iss 1, Pp 1-15 (2016)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Overexpression of Aurora A and B has been reported in a wide range of tumor types, including gastric cancer. Anti-angiogenesis has been considered as an important therapeutic modality in advanced gastric cancer. Here we identified a novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0ac9c55650e2e9041cc04b2398eace
http://link.springer.com/article/10.1186/s13046-016-0464-2
http://link.springer.com/article/10.1186/s13046-016-0464-2
Autor:
Meifang Zhang, Xiongwen Zhang, Zhanguo Wang, Guozhi Tang, Zheng Hong Peng, Yiping Rong, Li Chen, Zhenshan Zhang, Jim Zhen Wu, Weixing Zhang, Lingjie Yu, Nan Zhang, Teng Feng, Jason Christopher Wong, Xihan Wu, Shijie Li
Publikováno v:
Journal of Medicinal Chemistry. 57:8026-8034
Herein we report the identification of a novel class of HDAC6 and HDAC8 selective inhibitors through a unique chemistry and phenotypic screening strategy. Tetrahydroisoquinoline 12 was identified as a potent HDAC6 and HDAC8 dual inhibitor from a focu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9305de33ef5757d75b099d6ca082b4
https://doi.org/10.1021/jm5008962
https://doi.org/10.1021/jm5008962
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1999 9(18):2635-2638
Autor:
Liu, Wang, Lu, Yu, Xiaoping Chai, Liu, Xiao, Zhu, Tong, Xihan Wu, Yanfen Fang, Liu, Xuan, Xiongwen Zhang
The inhibitory activities of novel TY derivatives against Aurora A and B kinases and proliferation of MGC-803 cells. Figure S1. Time evolution of root-mean-square deviations (RMSD) of backbone atoms during MD simulations. (PDF 224Â kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bba16044b420e9414b570aae3d0239b
Autor:
Lu Xianping, Zheng Hong Peng, Lichun Feng, Lei Guo, She Jin, Yun He, Song Pan, Junli Chen, Zhenshan Zhang, Shan Song, Yiping Rong, Li Chen, Ying Ji, Chao Zhang, Shijie Li, Chunping Xu, Rong Zhao, Yongfu Liu, Yi Ren, Xihan Wu, Weixing Zhang, Xianfeng Lin, Tai-Guang Jin, Jason Christopher Wong, Taiping Chen, Jie Cai, Dawei Chen, Jianghua Mei, Meifang Zhang, Shuang Ren, Chungen Liang, Weili Zhao, Mingwei Zhou, Xiongwen Zhang, Zhanguo Wang, Zhiqiang Ning, Guozhi Tang, Desi Pan, Nan Zhang
Publikováno v:
Journal of Medicinal Chemistry. 55:8903-8925
Herein, we describe the pharmacokinetic optimization of a series of class-selective histone deacetylase (HDAC) inhibitors and the subsequent identification of candidate predictive biomarkers of hepatocellular carcinoma (HCC) tumor response for our cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fd7245bd2373bb888a6adb8825e024
https://doi.org/10.1021/jm3011838
https://doi.org/10.1021/jm3011838