Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Xigong Liu"'
Publikováno v:
Molecules, Vol 25, Iss 2, p 419 (2020)
The oxidative, dearomative cross-dehydrogenative coupling of indoles with various C-H nucleophiles is developed. This process features a broad substrate scope with respect to both indoles and nucleophiles, affording structurally diverse 2,2-disubstit
Externí odkaz:
https://doaj.org/article/c732bb06e0164e799ed3ecc832d4261c
Publikováno v:
Chinese Journal of Chemistry. 40:1681-1686
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad2c2725bc03b1b03516503b82e87f21
https://doi.org/10.1002/cjoc.202200113
https://doi.org/10.1002/cjoc.202200113
Publikováno v:
Synthesis. 54:421-428
Reported here is an efficient enantioselective transfer hydrogenation of cyclic oxocarbenium ions generated in situ through collapse of the corresponding acetal substrates. The asymmetric approach provides straightforward access to a variety of chira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edfe6951ecde48eecfccfbbb18ccfa2b
https://doi.org/10.1055/a-1643-8526
https://doi.org/10.1055/a-1643-8526
Publikováno v:
Angewandte Chemie. 133:18647-18651
The asymmetric construction of vicinal quaternary carbon stereocenters with at least one moiety in acyclic systems is a formidable challenge. We disclose a solution involving diastereo- and enantioselective oxidative 1,6-conjugate addition. The pract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f30fab1e57a82e97aa7326ac58b5faa
https://doi.org/10.1002/ange.202105594
https://doi.org/10.1002/ange.202105594
Publikováno v:
Synlett. 31:1619-1622
Pre-synthesized δ-CF3-δ-aryl-disubstituted para-quinone methides bearing δ-substituents were identified as isolable and storable substrates for 1,6-arylation reactions. A broad range of electron-rich arenes and heteroarenes participated in the ary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abd9f8a0b0d7f515bbbcbb3155da3dc5
https://doi.org/10.1055/s-0040-1706408
https://doi.org/10.1055/s-0040-1706408
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 151:971-979
Antimicrobial screening of an in-house library containing both natural products and synthetic compounds identified a bisindole molecule as a selective antibacterial hit. Further evaluation and structural modification afforded a series of dimeric indo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ea3b32709a3592358b90abbe7ee65eb
https://doi.org/10.1007/s00706-020-02629-y
https://doi.org/10.1007/s00706-020-02629-y
Publikováno v:
Organic Chemistry Frontiers. 7:2526-2530
Diarylmethyl alkynes with chirality at the propargylic position are privileged building blocks in many biologically important molecules. However, catalytic asymmetric access to such moieties has remained underdeveloped. Herein, we described a one-pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2529183f5ec0b14e0d15509211649ef
https://doi.org/10.1039/d0qo00811g
https://doi.org/10.1039/d0qo00811g
Autor:
Xigong Liu, Changyin Zhao, Kuiyong Jia, Jiarun Liu, Jiancheng Huang, Rongxiu Zhu, Tianxing Du
Publikováno v:
Synthesis. 52:763-768
A metal-free oxidative dearomatization of indoles with aromatic ketones mediated by TEMPO oxoammonium salt is described. The dearomatization proceeds smoothly and displays a broad substrate scope with respect to both indoles and aromatic ketones in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53f8bef813ad6859386f188e4cdb0456
https://doi.org/10.1055/s-0039-1691528
https://doi.org/10.1055/s-0039-1691528
Autor:
Ge Pan, Lei Liu, Yahong Cheng, Xigong Liu, Weiqiang Jing, Jing Qin, Sifeng Qu, Xia Sun, Kongkai Zhu
Publikováno v:
Bioorganicmedicinal chemistry. 32
Progesterone receptor (PR) antagonists have been found to be effective for treating certain human cancers. However, the steroidal structure of PR antagonists could bind to other hormone receptors, thus leading to serious side effects. On the other ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b801907b0ce13c9e25063520a2d942d
https://pubmed.ncbi.nlm.nih.gov/33461148
https://pubmed.ncbi.nlm.nih.gov/33461148
Publikováno v:
Molecules, Vol 25, Iss 2, p 419 (2020)
Molecules
Volume 25
Issue 2
Molecules
Volume 25
Issue 2
The oxidative, dearomative cross-dehydrogenative coupling of indoles with various C-H nucleophiles is developed. This process features a broad substrate scope with respect to both indoles and nucleophiles, affording structurally diverse 2,2-disubstit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4926dbd225db9cb3b495c538130bf25b
https://www.mdpi.com/1420-3049/25/2/419
https://www.mdpi.com/1420-3049/25/2/419