Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Xigang, Jing"'
Autor:
Tzong-Jin Wu, Michelle Teng, Xigang Jing, Kirkwood A. Pritchard, Billy W. Day, Stephen Naylor, Ru-Jeng Teng
Publikováno v:
Cells, Vol 13, Iss 21, p 1774 (2024)
Bronchopulmonary dysplasia (BPD) is the most common complication of prematurity. Oxidative stress (OS) and inflammation are the major contributors to BPD. Despite aggressive treatments, BPD prevalence remains unchanged, which underscores the urgent n
Externí odkaz:
https://doaj.org/article/65800d9b2d2344119e42c64f45931fd4
Autor:
Tzong-Jin Wu, Xigang Jing, Michelle Teng, Kirkwood A. Pritchard, Billy W. Day, Stephen Naylor, Ru-Jeng Teng
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 889 (2024)
Bronchopulmonary dysplasia (BPD) is a lung complication of premature births. The leading causes of BPD are oxidative stress (OS) from oxygen treatment, infection or inflammation, and mechanical ventilation. OS activates alveolar myeloid cells with su
Externí odkaz:
https://doaj.org/article/d53f01a2479e44c190b8e7a780ca6837
Autor:
Kirkwood A Pritchard, Xigang Jing, Michelle Teng, Clive Wells, Shuang Jia, Adeleye J Afolayan, Jason Jarzembowski, Billy W Day, Stephen Naylor, Martin J Hessner, G Ganesh Konduri, Ru-Jeng Teng
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0269564 (2022)
Myeloperoxidase (MPO), oxidative stress (OS), and endoplasmic reticulum (ER) stress are increased in the lungs of rat pups raised in hyperoxia, an established model of bronchopulmonary dysplasia (BPD). However, the relationship between OS, MPO, and E
Externí odkaz:
https://doaj.org/article/0e0e60295b3e42c7bc4e0afe473ef142
Autor:
Xigang Jing, Shuang Jia, Maggie Teng, Day, Billy W., Afolayan, Adeleye J., Jarzembowski, Jason A., Chien-Wei Lin, Hessner, Martin J., Pritchard Jr., Kirkwood A., Naylor, Stephen, Ganesh Konduri, G., Ru-Jeng Teng
Publikováno v:
American Journal of Respiratory Cell & Molecular Biology; Feb2024, Vol. 70 Issue 2, p94-109, 16p
Autor:
Xigang Jing, Dustin P. Martin, Ru-Jeng Teng, Stephen Naylor, Girija G. Konduri, Neil Hogg, Billy W. Day, Kirkwood A. Pritchard, Aaron Haefke
Publikováno v:
Free Radic Biol Med
Bronchopulmonary dysplasia (BPD) is caused primarily by oxidative stress and inflammation. To induce BPD, neonatal rat pups were raised in hyperoxic (>90% O2) environments from day one (P1) until day ten (P10) and treated with N-acetyl-lysyltyrosylcy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c953b4a7819d0445811ae42f3d7ba53f
https://doi.org/10.1016/j.freeradbiomed.2021.02.006
https://doi.org/10.1016/j.freeradbiomed.2021.02.006
Autor:
Hao Zhang, Xigang Jing, Yang Shi, Hao Xu, Jianhai Du, Tongju Guan, Dorothee Weihrauch, Deron W. Jones, Weiling Wang, David Gourlay, Keith T. Oldham, Cheryl A. Hillery, Kirkwood A. Pritchard, Jr.
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 11, Pp 3016-3029 (2013)
Myeloperoxidase (MPO) plays important roles in disease by increasing oxidative and nitrosative stress and oxidizing lipoproteins. Here we report N-acetyl lysyltyrosylcysteine amide (KYC) is an effective inhibitor of MPO activity. We show KYC inhibits
Externí odkaz:
https://doaj.org/article/ea916cdff05b4e8b905ac1c011947594
Autor:
Hao Zhang, Hao Xu, Dorothee Weihrauch, Deron W. Jones, Xigang Jing, Yang Shi, David Gourlay, Keith T. Oldham, Cheryl A. Hillery, Kirkwood A. Pritchard, Jr.
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 11, Pp 3009-3015 (2013)
Activated leukocytes and polymorphonuclear neutrophils (PMN) release myeloperoxidase (MPO), which binds to endothelial cells (EC), is translocated, and generates oxidants that scavenge nitric oxide (NO) and impair EC function. To determine whether MP
Externí odkaz:
https://doaj.org/article/588656a33fe543a18bcd6e1e6e63105c
Publikováno v:
International Journal of Medical Sciences
Breast cancer is the most common cancer in women worldwide. “Breast cancer” encompasses a broad spectrum of diseases (i.e., subtypes) with significant epidemiological, clinical, and biological heterogeneity. Each of these subtypes has a different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28409a593d97e46eeb0abc1c5e9c8e91
https://doi.org/10.7150/ijms.49544
https://doi.org/10.7150/ijms.49544
Autor:
Amber Majnik, Teresa Michalkiewicz, Brianna Entringer, Xigang Jing, Xingrao Ke, Robert H. Lane, Girija G. Konduri, Pengyuan Liu, Pui Y. Lai, Alison J. Kriegel
Publikováno v:
Physiol Genomics
Background: Fetal growth restriction (FGR) is a major risk factor for bronchopulmonary dysplasia (BPD). Maternal stress and poor diet are linked to FGR. Effect of perinatal stress on lung development remains unknown. Objective: Using a murine model o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3aaafa1f962a3ee3845faa4f3613ec
https://doi.org/10.1152/physiolgenomics.00016.2019
https://doi.org/10.1152/physiolgenomics.00016.2019
Autor:
Robert H. Lane, Xigang Jing, Girija G. Konduri, Xingrao Ke, Yi-Wen Huang, Hollis Johnson, Teresa Michalkiewicz
Publikováno v:
Physiological Genomics. 50:828-836
Decreased expression of endothelial nitric oxide synthase (eNOS), a key mediator of perinatal transition, characterizes persistent pulmonary hypertension of the newborn (PPHN) in neonates and a fetal lamb model; the mechanisms are unclear. We investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020e04910966f0c10dad193d2f1cbdcd
https://doi.org/10.1152/physiolgenomics.00047.2018
https://doi.org/10.1152/physiolgenomics.00047.2018