Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Xiefan, Fang"'
Publikováno v:
FEBS Open Bio, Vol 11, Iss 8, Pp 2364-2382 (2021)
We previously found that DNA methyltransferase 3a (DNMT3a) plays an important role in regulating embryonic cardiomyocyte gene expression, morphology, and function. In this study, we investigated the role of the most abundant DNMT in mammalian cells,
Externí odkaz:
https://doaj.org/article/66be8a155d704192813463ad529cae02
Autor:
Reyna Cristina Colli-Dula, Xiefan Fang, David Moraga-Amador, Nacira Albornoz-Abud, Roberto Zamora-Bustillos, Ana Conesa, Omar Zapata-Perez, Diego Moreno, Emanuel Hernandez-Nuñez
Publikováno v:
Data in Brief, Vol 20, Iss , Pp 1500-1509 (2018)
Benzo(a)pyrene (BaP), the prototype of polycyclic aromatic hydrocarbons, is known to exhibits genotoxic and carcinogenic effects promoting molecular impacts. The dataset presented here is associated with the research article paper entitled “Transcr
Externí odkaz:
https://doaj.org/article/ad43df1c0de54f1ab02fb45bb6bdfe17
Autor:
Xiaomeng Dai, Jun Xue, Jianli Hu, Sheng-li Yang, George G. Chen, Paul B.S. Lai, Chao Yu, Cui Zeng, Xiefan Fang, Xiaoli Pan, Tao Zhang
Publikováno v:
Translational Oncology, Vol 10, Iss 4, Pp 511-517 (2017)
BACKGROUND: Recurrence or metastasis of hepatocellular carcinoma (HCC) is mainly intrahepatic after curative resection, demonstrating that the peritumoral environment is important but often neglected. Programmed death ligand 1 (PD-L1) in intratumoral
Externí odkaz:
https://doaj.org/article/fcece2c240e042fabb998fa05c876704
A Nanoarchitectonic Approach Enables Triple Modal Synergistic Therapies To Enhance Antitumor Effects
Autor:
Zhimin Mo, Qiuting Li, Kan Zhao, Qi Xu, Han Hu, Xu Chen, Yuxuan Luo, Bin Chi, Liping Liu, Xiefan Fang, Guangfu Liao, Zushun Xu, Jing Wang, Shengli Yang
Publikováno v:
ACS Applied Materials & Interfaces. 14:10001-10014
Improvement of antitumor effects relies on the development of biocompatible nanomaterials and combination of various therapies to produce synergistic effects and avoid resistance. In this work, we developed GBD-Fe, a nanoformulation that effectively
Autor:
Lieqi Tang, Xiefan Fang, Steven P Winesett, Catherine Y Cheng, Henry J Binder, Scott A Rivkees, Sam X Cheng
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171045 (2017)
Mammalian colonic epithelia consist of cells that are capable of both absorbing and secreting Cl-. The present studies employing Ussing chamber technique identified two opposing short-circuit current (Isc) responses to basolateral bumetanide in rat d
Externí odkaz:
https://doaj.org/article/f4e25e57c43a400aa4006b20dc91c784
Autor:
Li Zhang, Xiefan Fang, Bin Zhang, Li-Sheng Zhu, Meng-jun Qiu, Zhi-fan Xiong, Shengli Yang, Qiu-ting Li
Publikováno v:
International Journal of Medical Sciences
Background: The circadian rhythm is produced by multiple feedback loops formed by the core clock genes after transcription and translation, thus regulating various metabolic and physiological functions of the human body. We have shown previously that
Autor:
Xiefan, Fang, Stephen D, Tichenor
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 120:107247
In nonclinical studies, electrocardiograms (ECG) of cynomolgus monkey are recorded intermittently by external leads in manually restrained animals (snapshot recording) or continuously by jacketed external telemetry (JET) or implanted radiotelemetry t
Autor:
Daniela L Buscariollo, Xiefan Fang, Victoria Greenwood, Huiling Xue, Scott A Rivkees, Christopher C Wendler
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87547 (2014)
Evidence indicates that disruption of normal prenatal development influences an individual's risk of developing obesity and cardiovascular disease as an adult. Thus, understanding how in utero exposure to chemical agents leads to increased susceptibi
Externí odkaz:
https://doaj.org/article/6480dc0b142c4e3aac407bc531fc2193
Autor:
Meng-jun Qiu, Qin Xia, Xin Jiang, Yaobing Chen, Zhi-fan Xiong, Xiefan Fang, Shengli Yang, Li-Sheng Zhu, Qiu-ting Li
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
BackgroundIn recent years, immune checkpoint inhibitors have shown significant effects in a variety of solid tumors. However, due to the low incidence of small cell lung cancer (SCLC) and its unclear mechanism, immune checkpoints in SCLC have not bee
Publikováno v:
Molecules, Vol 21, Iss 3, p 344 (2016)
Tocotrienols (T3s) are a subclass of unsaturated vitamin E that have been extensively studied for their anti-proliferative, anti-oxidative and anti-inflammatory properties in numerous cancer studies. Recently, T3s have received increasing attention d
Externí odkaz:
https://doaj.org/article/a143356e3df044b9bba06270ea3349f3