Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Xiechao He"'
Autor:
Xin Luo, Yaoxi He, Chao Zhang, Xiechao He, Lanzhen Yan, Min Li, Ting Hu, Yan Hu, Jin Jiang, Xiaoyu Meng, Weizhi Ji, Xudong Zhao, Ping Zheng, Shuhua Xu, Bing Su
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
The off-target effects and on-target mutations of CRISPR editing in higher non-human primates are complex. Here the authors perform whole genome trio sequencing of rhesus monkeys and see no unexpected mutations.
Externí odkaz:
https://doaj.org/article/2010f5dcae11485db052f34044756f74
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25052 (2011)
Parthenogenetic embryonic stem cells are considered as a promising resource for regeneration medicine and powerful tools for developmental biology. A lot of studies have revealed that embryonic stem cells have distinct microRNA expression pattern and
Externí odkaz:
https://doaj.org/article/d3707cc75a994d9e8132b6cd5fe09f75
Autor:
Guizhong Cui, Su Feng, Yaping Yan, Li Wang, Xiechao He, Xi Li, Yanchao Duan, Jun Chen, Patrick P.L. Tam, Ke Tang, Ping Zheng, Wei Si, Naihe Jing, Guangdun Peng
SummaryDuring mammalian embryogenesis, spatial regulation of gene expression and cell signaling are functionally coupled with lineage specification, patterning of tissue progenitors and germ layer morphogenesis. While the mouse model has been instrum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0460961bf2f56a12b0b84b221039d07
https://doi.org/10.1101/2022.01.26.474719
https://doi.org/10.1101/2022.01.26.474719
Autor:
Yan Hu, Xudong Zhao, Chao Zhang, Min Li, Xin Luo, Yaoxi He, Shuhua Xu, Jin Jiang, Weizhi Ji, Ping Zheng, X. J. Meng, Lanzhen Yan, Bing Su, Xiechao He, Ting Hu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Nature Communications
Nature Communications
CRISPR-Cas9 is a widely-used genome editing tool, but its off-target effect and on-target complex mutations remain a concern, especially in view of future clinical applications. Non-human primates (NHPs) share close genetic and physiological similari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a05ed174d45f9431b9d4dfd06b4953
https://doaj.org/article/2010f5dcae11485db052f34044756f74
https://doaj.org/article/2010f5dcae11485db052f34044756f74
Autor:
Xingxu Huang, Ping Zheng, Zheng Wang, Cong Li, Jian-Kui Zhou, Lanzhen Yan, Huan-Zhi Chen, Xintian Hu, Yong-Gang Yao, Dong-Dong Qin, Longbao Lv, Xiang Li, Xiechao He, Zheng-Fei Hu, Xiangyu Shen
Publikováno v:
Cell Discovery
Cell Discovery, Vol 7, Iss 1, Pp 1-5 (2021)
Cell Discovery, Vol 7, Iss 1, Pp 1-5 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536512e073bcd3d19077f2a78c3d211f
https://pubmed.ncbi.nlm.nih.gov/34845196
https://pubmed.ncbi.nlm.nih.gov/34845196
Additional data file 1: is a DOC file with Supplemental Methods, Figures (S1, S2, S3, S4) and Tables (S1, S2, S3, S4). (DOC 1 MB)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a11fb9b80f4c5e5f32b751fc4db433c
Additional file of MicroRNA profiling of rhesus macaque embryonic stem cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fcf11c512dc8b1eb0c48f5bba69320d
Autor:
Jing-Dong J. Han, Chunli Sun, Yizhou Li, Ping Zheng, Dajian He, Denghui Liu, Lanzhen Yan, Xinyi Wang, Xiechao He
Publikováno v:
Genome Research. 28:1481-1493
Naive pluripotency exists in epiblast cells of mouse pre-implantation embryos. However, whether the naive pluripotency is transient or nonexistent in primate embryos remains unclear. Using RNA-seq in single blastomeres from 16-cell embryos through to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3e19b757c973c1b9f42b2ecde55d1c
https://doi.org/10.1101/gr.233437.117
https://doi.org/10.1101/gr.233437.117
Autor:
Xiechao He, Xian Xia, Dajian He, Denghui Liu, Shengbao Suo, Xinyi Wang, Jing-Dong J. Han, Ping Zheng
Publikováno v:
Genome Research. 27:567-579
Preimplantation embryogenesis encompasses several critical events including genome reprogramming, zygotic genome activation (ZGA), and cell-fate commitment. The molecular basis of these processes remains obscure in primates in which there is a high r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::807886b77dce60f21ac3354e9ab334c7
https://doi.org/10.1101/gr.198044.115
https://doi.org/10.1101/gr.198044.115
Autor:
Lanzhen Yan, Min Li, Qiushuo Shen, Ting Hu, Yuting Liu, Yan Hu, Cheng Li, Bing Su, Haixu Wu, Xiechao He, Can Wang, Fengyun Zhang, Xuerui Zeng, Xin Luo, Shihua Zhang, X. J. Meng, Tingting Li, Yingping Hou, Dachang Dang
Publikováno v:
Cell. 184:723-740.e21
Elucidating the regulatory mechanisms of human brain evolution is essential to understanding human cognition and mental disorders. We generated multi-omics profiles and constructed a high-resolution map of 3D genome architecture of rhesus macaque dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673fa79b9ec3a8b70219bcebcdfb62ab
https://doi.org/10.1016/j.cell.2021.01.001
https://doi.org/10.1016/j.cell.2021.01.001