Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Xidong, Feng"'
Autor:
Haoran Zhao, Yuchen Fang, Yuxiang Zhao, Zheng Tian, Weinan Zhang, Xidong Feng, Li Yu, Wei Li, Hulei Fan, Tiema Mu
Publikováno v:
Sensors, Vol 23, Iss 6, p 3345 (2023)
The passive optical network (PON) is widely used in optical fiber communication thanks to its low cost and low resource consumption. However, the passiveness brings about a critical problem that it requires manual work to identify the topology struct
Externí odkaz:
https://doaj.org/article/834d559718d54335bf83d834a516374a
Autor:
Nicholas G. Fox, Xiaodi Yu, Xidong Feng, Henry J. Bailey, Alain Martelli, Joseph F. Nabhan, Claire Strain-Damerell, Christine Bulawa, Wyatt W. Yue, Seungil Han
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
The iron-sulfur cluster (ISC) assembly complex is activated by frataxin (FXN) and Friedreich’s ataxia is caused by FXN deficiency. Here the authors present the 3.2 Å resolution cryo-EM structure of the human frataxin bound ISC complex and discuss
Externí odkaz:
https://doaj.org/article/8abcf6459af9457bb7545657bbc6ed8d
Autor:
Ariamala Gopalsamy, Ann E. Aulabaugh, Amey Barakat, Kevin C. Beaumont, Shawn Cabral, Daniel P. Canterbury, Agustin Casimiro-Garcia, Jeanne S. Chang, Ming Z. Chen, Chulho Choi, Robert L. Dow, Olugbeminiyi O. Fadeyi, Xidong Feng, Scott P. France, Roger M. Howard, Jay M. Janz, Jayasankar Jasti, Reema Jasuja, Lyn H. Jones, Amanda King-Ahmad, Kelly M. Knee, Jeffrey T. Kohrt, Chris Limberakis, Spiros Liras, Carlos A. Martinez, Kim F. McClure, Arjun Narayanan, Jatin Narula, Jonathan J. Novak, Thomas N. O’Connell, Mihir D. Parikh, David W. Piotrowski, Olga Plotnikova, Ralph P. Robinson, Parag V. Sahasrabudhe, Raman Sharma, Benjamin A. Thuma, Dipy Vasa, Liuqing Wei, A. Zane Wenzel, Jane M. Withka, Jun Xiao, Hatice G. Yayla
Publikováno v:
Journal of Medicinal Chemistry. 64:326-342
Sickle cell disease (SCD) is a genetic disorder caused by a single point mutation (β6 Glu → Val) on the β-chain of adult hemoglobin (HbA) that results in sickled hemoglobin (HbS). In the deoxygenated state, polymerization of HbS leads to sickling
Autor:
Xidong Feng, Ye Che, Adam M. Gilbert, Reto Horst, Kris A. Borzilleri, Matthew Merrill Hayward, Carolyn A. Leverett, James Schiemer, Yilin Meng, Justin I. Montgomery, Matthew F. Calabrese, Mark C. Noe, Daniel P. Uccello, Stephen P. Brown, Matthew Frank Brown, Yingrong Xu
Publikováno v:
Nature Chemical Biology. 17:152-160
Heterobifunctional chimeric degraders are a class of ligands that recruit target proteins to E3 ubiquitin ligases to drive compound-dependent protein degradation. Advancing from initial chemical tools, protein degraders represent a mechanism of growi
Autor:
Jie Ren1,2 jieren9806@gmail.com, Xidong Feng3 xidong.feng.20@ucl.ac.uk, Bo Liu4 benjaminliu.eecs@gmail.com, Xuehai Pan5 xuehaipan@pku.edu.cn, Yao Fu1 y.fu@ed.ac.uk, Luo Mai1 luo.mai@ed.ac.uk, Yaodong Yang4 yaodong.yang@pku.edu.cn
Publikováno v:
Journal of Machine Learning Research. 2023, Vol. 24, p1-14. 14p.
Publikováno v:
AAAI
Compressed sensing magnetic resonance imaging (CS-MRI) is a technique aimed at accelerating the data acquisition of MRI. While down-sampling in k-space proportionally reduces the data acquisition time, it results in images corrupted by aliasing artif
Publikováno v:
CIKM
Practical recommender systems experience a cold-start problem when observed user-item interactions in the history are insufficient. Meta learning, especially gradient based one, can be adopted to tackle this problem by learning initial parameters of
Autor:
Alain Martelli, Claire Strain-Damerell, Henry J. Bailey, Christine Bulawa, Xiaodi Yu, Seungil Han, Wyatt W. Yue, Nicholas G. Fox, Joseph F. Nabhan, Xidong Feng
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Nature Communications
Nature Communications
The core machinery for de novo biosynthesis of iron-sulfur clusters (ISC), located in the mitochondria matrix, is a five-protein complex containing the cysteine desulfurase NFS1 that is activated by frataxin (FXN), scaffold protein ISCU, accessory pr
Autor:
Wyatt W. Yue, Alain Martelli, Theresa Towle, Christine Bulawa, Joseph F. Nabhan, Renea Gooch, Xidong Feng, Tiffany Ma, Nicholas G. Fox, Jaimeen D. Majmudar
Publikováno v:
MedChemComm. 10:209-220
The mitochondrial acyl carrier protein (human ACPM, yeast Acp1) is an essential mitochondrial protein. Through binding of nascent acyl chains on the serine (S112)-bound 4′-phosphopantetheine (4′-PP) cofactor, ACPM is involved in mitochondrial fat
Autor:
Kathleen A. Farley, Parag Sahasrabudhe, Manjinder S. Lall, Justin Bellenger, Bruce Allen Lefker, Xidong Feng, Timothy L. Foley, Scott L. Hultgren, Dominik K. Kölmel, Jinqiao Wan, Bo Liu, Justin I. Montgomery, Anokha S. Ratnayake, Mark Edward Flanagan, Shi Chen, Laura J. Byrnes, Andre Shavnya, Tim F. Ryder
Publikováno v:
Bioorganicmedicinal chemistry. 41
The ability to predict chemical structure from DNA sequence has to date been a necessary cornerstone of DNA-encoded library technology. DNA-encoded libraries (DELs) are typically screened by immobilized affinity selection and enriched library members