Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Xicheng Sun"'
Autor:
Yanze Yin, Huijuan Dai, Xicheng Sun, Zhifeng Xi, Jiang Zhang, Yixiao Pan, Yongxin Huang, Xueyun Ma, Qiang Xia, Kang He
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 6, Pp n/a-n/a (2023)
Abstract Background Distant metastasis is a sign of poor prognosis for cancer patients. Extrahepatic liver cancer metastases commonly spread to the lung. Remodelling of the metastatic microenvironment is essential for tumour metastasis. Neutrophil‐
Externí odkaz:
https://doaj.org/article/71336698e48d45c18be6a083cbee23ef
Autor:
Mary A. De Groote, Thale C. Jarvis, Christina Wong, James Graham, Teresa Hoang, Casey L. Young, Wendy Ribble, Joshua Day, Wei Li, Mary Jackson, Mercedes Gonzalez-Juarrero, Xicheng Sun, Urs A. Ochsner
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Mycobacteria remain an important problem worldwide, especially drug resistant human pathogens. Novel therapeutics are urgently needed to tackle both drug-resistant tuberculosis (TB) and difficult-to-treat infections with nontuberculous mycobacteria (
Externí odkaz:
https://doaj.org/article/ef2513c2756f449390c815c0714411b7
Autor:
Jiaxiang Ding, Jiaheng Shi, Xiaomei Sun, Xin Lu, Xicheng Sun, Junhao Wang, Yuhang Ye, Shenghao Xu, Xiliang Luo
Publikováno v:
Analytical Chemistry. 94:12546-12551
Optical cross-reactive sensor arrays inspired by the mammalian olfactory system that can realize straightforward discrimination of plasma from cancer patients hold great potential for point-of-care diseases diagnostics. Herein, a pH programmed fluore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4994ac311dee32f45e58c079e2b57f2
https://doi.org/10.1021/acs.analchem.2c03245
https://doi.org/10.1021/acs.analchem.2c03245
Autor:
Swati Patel, Moti Chapagain, Clifford Mason, Matthew Gingrich, Shruti Athale, Wendy Ribble, Teresa Hoang, Joshua Day, Xicheng Sun, Thale Jarvis, Urs A Ochsner, David Howe, Tawanda Gumbo
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:2876-2885
Background Listeriosis is an orphan disease, which is nevertheless fatal in immunocompromised people. CRS0540 is a novel PolC DNA polymerase inhibitor that has demonstrated good in vitro and in vivo activity against Listeria monocytogenes. Methods Ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f704cf2a22ef227e475e294a6177cba
https://doi.org/10.1093/jac/dkac269
https://doi.org/10.1093/jac/dkac269
Autor:
Zijie Zhang, Yi Zhou, Huan Tong, Xicheng Sun, Lei Xia, Zicheng Lv, Junekong Yong, Yichi Wu, Xuelin Xiang, Fei Ding, Xiaolei Zuo, Fan Li, Hao Feng, Chunhai Fan, Qiang Xia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d9036a18868292665576f6646aabbad
https://doi.org/10.2139/ssrn.4401688
https://doi.org/10.2139/ssrn.4401688
Autor:
Urs A. Ochsner, Mary A. De Groote, Thale C. Jarvis, Hang Liu, Tessa Youmans, Teresa Hoang, Wendy Ribble, Joshua Day, Wei Li, Camron Pearce, Amanda Walz, Chandra M. Panthi, Binayak Rimal, Casey M. Stevens, Helen I. Zgurskaya, Mary Jackson, Diane Ordway, Mercedes Gonzalez-Juarrero, Xicheng Sun, Gyanu Lamichhane, Clifford Mason
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 138
The benzothiazole amide CRS0393 demonstrated excellent in vitro activity against nontuberculous mycobacteria (NTM), including M. abscessus isolates from cystic fibrosis (CF) patients, with minimum inhibitory concentrations (MICs) of ≤0.03-0.5 μg/m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88ef490e2ea0c40194904ea50d13af3
https://pubmed.ncbi.nlm.nih.gov/36470124
https://pubmed.ncbi.nlm.nih.gov/36470124
Autor:
Thale C. Jarvis, Wendy Ribble, Xicheng Sun, Teresa Hoang, Elizabeth McFaddin, Joshua Day, Casey L. Young, Mary Ann DeGroote, Christina Wong, James E. Graham, Urs A. Ochsner
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:3177-3181
From a high throughput screening of commercially available libraries against nontuberculous mycobacteria and Mycobacterium tuberculosis, numerous hits were identified with moderate activity. Extensive medicinal chemistry optimization has led to a ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4185634cd19d14839191b939bb7e32c3
https://doi.org/10.1016/j.bmcl.2018.08.026
https://doi.org/10.1016/j.bmcl.2018.08.026
Autor:
Thale C. Jarvis, Joshua Day, Wendy Ribble, Mary Jackson, Christina Wong, Xicheng Sun, Mary Ann De Groote, Casey L. Young, Urs A. Ochsner, Teresa Hoang, Mercedes Gonzalez-Juarrero, Wei Li, James E. Graham
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Frontiers in Microbiology
Frontiers in Microbiology, Vol 10 (2019)
Frontiers in Microbiology
Frontiers in Microbiology, Vol 10 (2019)
Mycobacteria remain an important problem worldwide, especially drug resistant human pathogens. Novel therapeutics are urgently needed to tackle both drug-resistant tuberculosis (TB) and difficult-to-treat infections with nontuberculous mycobacteria (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d45a258ef409ac593a89a1bdf054600
https://www.frontiersin.org/article/10.3389/fmicb.2018.02231/full
https://www.frontiersin.org/article/10.3389/fmicb.2018.02231/full
Autor:
Louis S. Green, Joan P. Blonder, Sarah Strong, Jian Qiu, Xicheng Sun, Jane P. Richards, Sarah C. Mutka, Jan Wasley, Adam Stout, Gary J. Rosenthal, Dorothy B. Colagiovanni
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:2338-2342
The enzyme S-nitrosoglutathione reductase (GSNOR) is a member of the alcohol dehydrogenase family (ADH) that regulates the levels of S-nitrosothiols (SNOs) through catabolism of S-nitrosoglutathione (GSNO). GSNO and SNOs are implicated in the pathoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d787f677d3e967787923e0d3bf15a0e
https://doi.org/10.1016/j.bmcl.2012.01.047
https://doi.org/10.1016/j.bmcl.2012.01.047
Autor:
Jane P. Richards, Aaron K. Patton, Lawrence Chun, Xicheng Sun, Louis S. Green, Gary J. Rosenthal
Publikováno v:
Biochemistry. 51:2157-2168
N6022 is a novel, first-in-class drug with potent inhibitory activity against S-nitrosoglutathione reductase (GSNOR), an enzyme important in the metabolism of S-nitrosoglutathione (GSNO) and in the maintenance of nitric oxide (NO) homeostasis. Inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3acde8b59693eb1f8d277e7d7622f35
https://doi.org/10.1021/bi201785u
https://doi.org/10.1021/bi201785u