Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Xicai Huang"'
Autor:
Xicai Huang1, Bennet, Andrew J.1 bennet@sfu.ca
Publikováno v:
Canadian Journal of Chemistry. Sep2004, Vol. 82 Issue 9, p1336-1340. 5p. 4 Diagrams, 1 Chart, 2 Graphs.
Autor:
Robert Blumenthal, Nga Pham, Amy Jacobs, Geneviève Nault, Chantal Soucy, Martin Robitaille, Dominique P. Bridon, Xicai Huang, W. Gregory Alvord, Nathalie Bousquet-Gagnon, Omar Quraishi, Nicholas Francella
Publikováno v:
Journal of Biological Chemistry. 282:32406-32413
Peptide inhibitors corresponding to sequences in the six helix bundle structure of the fusogenic portion (gp41) of the HIV envelope glycoprotein have been successfully implemented in preventing HIV entry. These peptides bind to regions in HIV gp41 tr
Autor:
Véronique Paradis, Martin Robitaille, Pieter van Wyk, Dominique P. Bridon, Karen Thibaudeau, Omar Quraishi, Jean-Paul Castaigne, Roger Leger, Xicai Huang, Chantal Soucy, Nathalie Bousquet-Gagnon
Publikováno v:
Bioconjugate Chemistry. 16:1000-1008
A series of human insulin maleimido derivatives with short and long linkers was synthesized by exploiting the variations in the pK(a) values and environment of the three amino groups present in the protein. The syntheses were accomplished in organic
Autor:
Corinne Benquet, Roger Leger, Dominique P. Bridon, Xicai Huang, Pieter van Wyk, Omar Quraishi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:841-845
Three peptide fragments of the kringle 5 region of plasminogen and their respective N- and C-terminus maleimido derivatives conjugated to Cys34 of human serum albumin were evaluated in vitro using a human umbilical vein endothelial cell (HUVEC) migra
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 2. :83-89
The spontaneous hydrolysis reactions of 2-(4-nitrophenoxy)tetrahydropyran (6a) and 2-(4-cyanophenoxy)tetrahydropyran (6b) are accelerated in the presence of α-cyclodextrin (α-CD), but are slowed by the addition of β-CD, γ-CD, or mono[2-O-(carboxy
Publikováno v:
Canadian Journal of Chemistry. 78:577-582
Three 2-deoxy-α-D-glucopyranosyl pyridinium tetrafluoroborates were tested for their binding affinity to a range of α-glucosidases and α-mannosidases. The α-isoquinolinium salt (11) binds approximately 275-fold more tightly to yeast α-glucosidas
Publikováno v:
The Journal of Peptide Research. 53:126-133
The preparation of a series of novel Cbz-Gln-Gly dipeptide derivatives is reported, wherein the gamma-carboxamide groups of the glutamine side chains have been modified to gamma-15N-anilides which are substituted in the para position with -NO2, -Cl,
Publikováno v:
Journal of the American Chemical Society. 120:1405-1409
The aqueous ethanolysis reactions of the adamantylideneadamantyl halides (2-Cl, 2-Br, and 2-I) exhibit Grunwald−Winstein sensitivity parameters (m) of 0.74 ± 0.06, 0.90 ± 0.01, and 0.88 ± 0.03 for the chloride, bromide, and iodide compounds, res
Autor:
Doug T. H. Chou, Raymond J. Batchelor, Frederick W. B. Einstein, Andrew J. Bennet, Xicai Huang
Publikováno v:
The Journal of Organic Chemistry. 63:575-581
The homoallylically substituted alcohols (1-OH and 3-OH) of the sterically congested alkene adamanylideneadamantane (1-H) react with acid catalysis in a solvent of 50% v/v acetic acid:50% v/v aqueous sulfuric acid at 110 degrees C to give a saturated
Publikováno v:
The Journal of Organic Chemistry. 62:8821-8825
The regioselectivity of the reaction of aniline with a series of N-protected aspartic and glutamic acid anhydrides was controlled through the choice of reaction solvent. In benzene, the formation of aspartic or glutamic acid α-anilides was favored,