Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Xiayun Yang"'
Autor:
Xiayun Yang, Qin Zhang, Shuxuan Li, Raman Devarajan, Binjie Luo, Zenglai Tan, Zixian Wang, Nikolaos Giannareas, Tomasz Wenta, Wenlong Ma, Yuqing Li, Yuehong Yang, Aki Manninen, Song Wu, Gong-Hong Wei
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-30 (2023)
Abstract Background Aberrant somatic genomic alteration including copy number amplification is a hallmark of cancer genomes. We previously profiled genomic landscapes of prostate cancer (PCa), yet the underlying causal genes with prognostic potential
Externí odkaz:
https://doaj.org/article/5ac07c8f5fb64b55b03685f77c3dbda4
Autor:
Nikolaos Giannareas, Qin Zhang, Xiayun Yang, Rong Na, Yijun Tian, Yuehong Yang, Xiaohao Ruan, Da Huang, Xiaoqun Yang, Chaofu Wang, Peng Zhang, Aki Manninen, Liang Wang, Gong-Hong Wei
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
The role of risk loci identified from genome-wide association studies in prostate cancer (PCa) progression remains poorly characterised. Here, the authors report enrichment of transcription factor genes within PCa risk-associated regions and germline
Externí odkaz:
https://doaj.org/article/68a5e6cf0a8e452ea0ab96cfa23424cf
Publikováno v:
Molecules, Vol 22, Iss 4, p 595 (2017)
Olaquindox, a feed additive, has drawn public attention due to its potential mutagenicity, genotoxicity, hepatoxicity and nephrotoxicity. The purpose of this study was to investigate the role of tuberous sclerosis complex (TSC2) pathways in olaquindo
Externí odkaz:
https://doaj.org/article/220fc5f57e2f47dd9f13a2be3dcf128e
Publikováno v:
Molecules, Vol 22, Iss 1, p 124 (2017)
Olaquindox, a quinoxaline 1,4-dioxide derivative, is widely used as a feed additive in many countries. The potential genotoxicity of olaquindox, hence, is of concern. However, the proper mechanism of toxicity was unclear. The aim of the present study
Externí odkaz:
https://doaj.org/article/3e48b47b9f5b41b689f572da493e6a70
Autor:
Tomasz Wenta, Anette Schmidt, Qin Zhang, Raman Devarajan, Prateek Singh, Xiayun Yang, Anne Ahtikoski, Markku Vaarala, Gong-Hong Wei, Aki Manninen
Publikováno v:
Oncogene. 41(30)
Loss of α6β4-dependent hemidesmosomal adhesions has been observed during prostate cancer progression. However, the significance and underlying mechanisms by which aberrant hemidesmosome assembly may modulate tumorigenesis remain elusive. Using an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea359fc0d3b8da9722848e42dbe038fb
https://pubmed.ncbi.nlm.nih.gov/35773413
https://pubmed.ncbi.nlm.nih.gov/35773413
Autor:
Anne Ahtikoski, Xiayun Yang, Anette Schmidt, Markku H. Vaarala, Raman Devarajan, Prateek Singh, Qin Zhang, Aki Manninen, Gong-Hong Wei, Tomasz Wenta
Loss of α6β4-dependent hemidesmosomes has been observed during prostate cancer progression. However, the significance and underlying mechanisms by which aberrant hemidesmosome assembly may modulate tumorigenesis remain elusive. Using an extensive C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27c4293b03ef3b109cedd1d8f04afe2e
https://doi.org/10.1101/2021.11.08.467671
https://doi.org/10.1101/2021.11.08.467671
Publikováno v:
Food and Chemical Toxicology. 108:148-160
Olaquindox, a quinoxaline 1,4-di-N-oxide, is known as an antibacterial agent and feed additive to treat bacterial infections and promote animal growth. However, the potential mechanism of toxicity is still unknown. The present study aims to explore t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd5c54127695c554ad419e04ba837c9
https://doi.org/10.1016/j.fct.2017.07.054
https://doi.org/10.1016/j.fct.2017.07.054
Autor:
Xilong Xiao, Chongshan Dai, Xiayun Yang, Shusheng Tang, Shen Zhang, Sijun Deng, Chaoming Zhang, Yan Zhou
Publikováno v:
Toxicology Mechanisms and Methods. 26:301-310
Quinocetone (QCT, 3-methyl-2-quinoxalin benzenevinylketo-1, 4-dioxide) is widely used as a veterinary drug and animal feed additive in China. Although it promotes growth and improves feed efficiency, QCT's in vitro and in vivo toxicities remain uncer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2797d8227f8d01eebaabd9564501212
https://doi.org/10.3109/15376516.2016.1172690
https://doi.org/10.3109/15376516.2016.1172690
Publikováno v:
Food and Chemical Toxicology. 88:1-12
Furazolidone (FZD), a synthetic nitrofuran with a broad spectrum of antimicrobial activities, has been shown to exhibit marked genotoxity and cytotoxicity in vitro, but the proper mechanism was unclear. P21(Waf1/Cip1) (p21), a cyclin-dependent kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f7816aef137a6b7db490dfdb2e4f5a
https://doi.org/10.1016/j.fct.2015.12.004
https://doi.org/10.1016/j.fct.2015.12.004
Publikováno v:
Journal of cellular physiology. 233(6)
Bcl-2 homologous antagonist/killer (BAK1) is a critical regulator of mitochondrial apoptosis. Although upregulation of BAK1 induces apoptosis has been established, the underlying molecular mechanism is far from clear. 4,4'-diisothiocyanostilbene-2,2'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7026ed9607872e41976353d021a28ae
https://pubmed.ncbi.nlm.nih.gov/29231977
https://pubmed.ncbi.nlm.nih.gov/29231977