Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Xiayun Cheng"'
Autor:
Allyn T. Londregan, Karlygash Aitmakhanova, James Bennett, Laura J. Byrnes, Daniel P. Canterbury, Xiayun Cheng, Thomas Christott, Jennifer Clemens, Steven B. Coffey, João M. Dias, Matthew S. Dowling, Gillian Farnie, Oleg Fedorov, Kimberly F. Fennell, Vicki Gamble, Carina Gileadi, Charline Giroud, Michael R. Harris, Brett D. Hollingshead, Kilian Huber, Magdalena Korczynska, Kimberly Lapham, Paula M. Loria, Arjun Narayanan, Dafydd R. Owen, Brigitt Raux, Parag V. Sahasrabudhe, Roger B. Ruggeri, Laura Díaz Sáez, Ingrid A. Stock, Benjamin A. Thuma, Andy Tsai, Alison E. Varghese
Publikováno v:
Journal of medicinal chemistry.
A series of small-molecule YEATS4 binders have been discovered as part of an ongoing research effort to generate high-quality probe molecules for emerging and/or challenging epigenetic targets. Analogues such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f200505c5effa14e470509072c0e10b
https://pubmed.ncbi.nlm.nih.gov/36562986
https://pubmed.ncbi.nlm.nih.gov/36562986
Autor:
Rongbiao Tong, Daniel P. Canterbury, Xiayun Cheng, Alexandria P. Taylor, Guodong Zhao, Scott W. Bagley, Peter Mikochik
Publikováno v:
Organic letters. 22(2)
The first Pd-catalyzed arylation of aza-Achmatowicz rearrangement products with arylboronic acids is achieved, providing versatile 2-aryldihydropyridinones for facile synthesis of highly functionalized 2-arylpiperidines. Key to this arylation is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b2ac8e7f4f8379a3d438d1f7230ce3
https://pubmed.ncbi.nlm.nih.gov/31880455
https://pubmed.ncbi.nlm.nih.gov/31880455
Autor:
Xiayun Cheng, Glenn C. Micalizio
Publikováno v:
Journal of the American Chemical Society. 138:1150-1153
An asymmetric approach to the synthesis of neurotrophic seco-prezizaane sesquiterpenes is described that is based on the strategic application of a hydroxyl-directed metallacycle-mediated [2 + 2 + 2] annulation and an intramolecular radical cyclizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0cb7c296966e48b97c7f5cbfe62ec3
https://doi.org/10.1021/jacs.5b12694
https://doi.org/10.1021/jacs.5b12694
Autor:
Glenn C. Micalizio, Xiayun Cheng
This chapter describes our journey associated with efforts to prepare members of the seco-prezizaane family of neurotrophic natural products. Efforts sprung from a chemical foundation consisting of a new metallacycle-mediated annulative cross-couplin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9715c8823fa9f7b3597e5915cd41b38
https://doi.org/10.1016/b978-0-12-811790-3.00002-x
https://doi.org/10.1016/b978-0-12-811790-3.00002-x
Autor:
Glenn C. Micalizio, Xiayun Cheng
Publikováno v:
Organic Letters
In efforts directed toward the synthesis of seco-prezizaane sesquiterpenoids, a stereoselective annulation reaction has been developed between 4-hydroxy-1,6-enynes and TMS-alkynes that delivers cross-conjugated triene-containing hydroindanes. Contrar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356d59750f78c8cfc9b081bc5eb017b2
http://europepmc.org/articles/PMC4184447
http://europepmc.org/articles/PMC4184447
Autor:
Mika Nakashige, Claudio Aquino, Glenn C. Micalizio, Valer Jeso, Haruki Mizoguchi, Xiayun Cheng
Publikováno v:
Journal of the American Chemical Society
Angularly substituted trans-fused hydroindanes are now accessible by the direct and convergent union of trimethylsilyl (TMS)-alkynes with 4-hydroxy-1,6-enynes by a process that forges three C–C bonds, one C–H bond, and two new stereocenters. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0da772e9aa7c7348caa229147ffbd74
https://doi.org/10.1021/ja504374j
https://doi.org/10.1021/ja504374j
Autor:
Guodong Zhao, Canterbury, Daniel P., Taylor, Alexandria P., Xiayun Cheng, Mikochik, Peter, Bagley, Scott W., Rongbiao Tong
Publikováno v:
Organic Letters; Jan2020, Vol. 22 Issue 2, p458-463, 6p
Autor:
Stephen P. Waters, Xiayun Cheng
Publikováno v:
Organic Letters. 15:4226-4229
A concise, enantioselective total synthesis of the Lycopodium alkaloid (-)-lyconadin C was achieved in 12 steps and high overall yield. Key features include construction of a luciduline congener through Mannich-type cyclization and a one-pot, tandem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90b55ddc1755937f2f51901d19c6ba7
https://doi.org/10.1021/ol401954f
https://doi.org/10.1021/ol401954f
Autor:
Glenn C. Micalizio, Xiayun Cheng
Publikováno v:
ChemInform. 46
In efforts directed toward the synthesis of seco-prezizaane sesquiterpenoids, a stereoselective annulation reaction is developed between 4-hydroxy-1,6-enynes (I) and Tms-alkynes (II) affording cross-conjugated triene-containing hydroindanes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7ca9241d474fa53cd7f7bb4ef081d36
https://doi.org/10.1002/chin.201513041
https://doi.org/10.1002/chin.201513041
Autor:
Mika Nakashige, Claudio Aquino, Xiayun Cheng, Valer Jeso, Glenn C. Micalizio, Haruki Mizoguchi
Publikováno v:
ChemInform. 46
Hydroindanes are formed from TMS-alkynes and 4-hydroxy-1,6-enynes in the presence of Ti(OiPr)4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de4aa4a5955c3973392a957a0f00c093
https://doi.org/10.1002/chin.201502101
https://doi.org/10.1002/chin.201502101