Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Xiayun Chen"'
Autor:
Mengyi Yan, Xiayun Chen, Xiaotong Li, Qianqian Liu, Baixue Yu, Yi Cen, Wei Zhang, Yibin Liu, Xinxuan Li, Ying Chen, Tao Wang, Shiying Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4118-4133 (2024)
The immunosuppressive phenotype of tumor cells extensively attenuates the immune activation effects of traditional treatments. In this work, a transferrin receptor (TfR) targeted immunostimulant (PTI) is fabricated for photodynamic immunotherapy agai
Externí odkaz:
https://doaj.org/article/e82264c1b8c34b5596ecc6997c5f01a8
Publikováno v:
Materials & Design, Vol 235, Iss , Pp 112378- (2023)
Therapy-induced immunogenic cell death (ICD) can trigger a burst release of immunostimulatory signals, but some of them can be converted into immunosuppressive factors to extensively restrict systemic anti-tumor immunity. In this work, a self-deliver
Externí odkaz:
https://doaj.org/article/bc0da49d7d6a44fa94b0f266c0402a7f
Autor:
Yi Cen, Xiayun Chen, Yibin Liu, Baixue Yu, Mengyi Yan, Ni Yang, Renjiang Kong, Shiying Li, Huihui Ti, Hong Cheng
Publikováno v:
Journal of Controlled Release. 358:654-666
Autor:
Yibin, Liu, Fuan, Deng, Rongrong, Zheng, Xiayun, Chen, Linping, Zhao, Baixue, Yu, Ali, Chen, Xueyan, Jiang, Hong, Cheng, Shiying, Li
Publikováno v:
Journal of Colloid and Interface Science. 612:562-571
Tumor vascular blockade is a promising strategy for adjuvant cancer treatment. In this work, a self-delivery nanomedicine is developed based on a vascular disruptor and photosensitizer for tumor synergistic therapy. Specifically, this nanomedicine (d
Autor:
Yi-Bin Liu, Xiayun Chen, Xian‐Tong Chen, Rong-Rong Zheng, Xi-Yong Yu, Hong Cheng, Chang Wang, Ling-Shan Liu, Shi-Ying Li, Lin-Ping Zhao
Publikováno v:
Journal of Controlled Release. 336:159-168
Apoptosis resistance of tumor cells often results in chemoresistance and treatment failure in clinic. In this work, a Cu2+-coordinated morusin/doxorubicin biological organizer (designated as COMBO) is designed to combat cellular resistance to apoptos
Autor:
Rong-Rong Zheng, Lin-Ping Zhao, Xiayun Chen, Ni Yang, Chang Wang, Hong Cheng, Xi-Yong Yu, Shi-Ying Li, A-Li Chen, Runtian Guan
Publikováno v:
Chemical Communications. 57:4134-4137
A porphysome-based photodynamic O2 economizer (P-PAT) is prepared for hypoxic tumor therapy. The self-assembled porphyrin bilayers of P-PAT possess high loading capacity to atovaquone (ATO) (nearly 70%), which could restrain mitochondrial respiration
Autor:
Ni Yang, Rong-Rong Zheng, Runtian Guan, A-Li Chen, Xi-Yong Yu, Hong Cheng, Xiayun Chen, Shi-Ying Li, Lin-Ping Zhao, Ling-Shan Liu
Publikováno v:
Biomaterials. 275
Amplifying oxidative stress to break intracellular redox homeostasis could accelerate tumor cell death. In this work, a self-delivery oxidative stress amplifier is developed for chemotherapy sensitized immunotherapy. By virtue of the π-π stacking a
Autor:
Rongrong, Zheng, Xiayun, Chen, Linping, Zhao, Ni, Yang, Runtian, Guan, Ali, Chen, Xiyong, Yu, Hong, Cheng, Chang, Wang, Shiying, Li
Publikováno v:
Chemical communications (Cambridge, England). 57(34)
A porphysome-based photodynamic O2 economizer (P-PAT) is prepared for hypoxic tumor therapy. The self-assembled porphyrin bilayers of P-PAT possess high loading capacity to atovaquone (ATO) (nearly 70%), which could restrain mitochondrial respiration
Autor:
Xiayun Chen, Rongrong Zheng, Linping Zhao, Renjiang Kong, Ni Yang, Yibin Liu, Ali Chen, Chang Wang, Hong Cheng, Shiying Li
Publikováno v:
Chemical Engineering Journal. 435:134783
Autor:
Rong-Rong Zheng, Chu-Yu Huang, Fu-An Deng, Yi-Bin Liu, Xiayun Chen, Shi-Ying Li, Hong Cheng, Xi-Yong Yu, Lin-Ping Zhao, Jia-Qi Huang
Publikováno v:
ACS nano. 14(12)
Self-delivery of photosensitizer and immune modulator to tumor site is highly recommendable to improve the photodynamic immunotherapy yet remains challenging. Herein, self-delivery photoimmune stimulators (designated as iPSs) are developed for photod