Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Xiayun, Wan"'
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Relapse is common in remitted patients with major depressive disorder (MDD). Arketamine, an (R)-enantiomer of ketamine, has persistent prophylactic actions in an inflammatory model of depression. However, the precise mechanisms underlying th
Externí odkaz:
https://doaj.org/article/14d4644e5abb4c0caa0e40b099c8973b
Publikováno v:
Neurobiology of Disease, Vol 189, Iss , Pp 106348- (2023)
3,4-Methylenedioxymethamphetamine (MDMA) is the most widely used illicit substance worldwide. Nevertheless, recent observational studies demonstrated that lifetime MDMA use among U.S. adults was associated with a lower risk of depression and suicide
Externí odkaz:
https://doaj.org/article/b99b74a470064b50bdf194786c4569e9
Autor:
Li Ma, Long Wang, Lijia Chang, Jiajing Shan, Youge Qu, Xingming Wang, Xiayun Wan, Yuko Fujita, Kenji Hashimoto
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract (R,S)-ketamine is known to elicit persistent prophylactic effects in rodent models of depression. However, the precise molecular mechanisms underlying its action remain elusive. Using RNA-sequencing analysis, we searched for novel molecular
Externí odkaz:
https://doaj.org/article/df5f5097b6214dbdbd5dcd4d24b0004a
Autor:
Hiroyo Shinno-Hashimoto, Akifumi Eguchi, Akemi Sakamoto, Xiayun Wan, Yaeko Hashimoto, Yuko Fujita, Chisato Mori, Masahiko Hatano, Hiroyuki Matsue, Kenji Hashimoto
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Imiquimod (IMQ) is widely used as animal model of psoriasis, a chronic inflammatory skin disorder. Although topical application of IMQ to back skin causes splenomegaly in mice, how the spleen affects the psoriasis-like phenotype of IMQ-treat
Externí odkaz:
https://doaj.org/article/3a86673012ee4dd28ffc21f7010f7c01
Autor:
Li Ma, Jiancheng Zhang, Yuko Fujita, Youge Qu, Jiajing Shan, Xiayun Wan, Xingming Wang, Tamaki Ishima, Kenta Kobayashi, Long Wang, Kenji Hashimoto
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract (R, S)-ketamine has prophylactic antidepressant-like effects in rodents; however, the precise molecular mechanisms underlying its action remain unknown. Using RNA-sequencing analysis, we searched novel molecular target(s) that contribute to
Externí odkaz:
https://doaj.org/article/f32c469a36c84859a13c5db52a93723a
Autor:
Xiayun Wan, Akifumi Eguchi, Akemi Sakamoto, Yuko Fujita, Yong Yang, Youge Qu, Masahiko Hatano, Chisato Mori, Kenji Hashimoto
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 27, Iss , Pp 100573- (2023)
The spleen is a key immune-related organ that plays a role in communication between the brain and the immune system through the brain–spleen axis and brain–gut–microbiota axis. However, how the gut microbiota affects spleen and brain function r
Externí odkaz:
https://doaj.org/article/b09c183c2e494510ac27cc4cee4adb38
Autor:
Xingming Wang, Akifumi Eguchi, Yong Yang, Lijia Chang, Xiayun Wan, Jiajing Shan, Youge Qu, Li Ma, Chisato Mori, Jianjun Yang, Kenji Hashimoto
Publikováno v:
Neurobiology of Disease, Vol 176, Iss , Pp 105951- (2023)
Multiple sclerosis (MS) is the most common demyelinating disease that attacks the central nervous system. Dietary intake of cuprizone (CPZ) produces demyelination resembling that of patients with MS. Given the role of the vagus nerve in gut–microbi
Externí odkaz:
https://doaj.org/article/433f4dbddf26483f83aae9dde784c582
Autor:
Xingming Wang, Lijia Chang, Xiayun Wan, Yunfei Tan, Youge Qu, Jiajing Shan, Yong Yang, Li Ma, Kenji Hashimoto
Publikováno v:
Neurobiology of Disease, Vol 170, Iss , Pp 105779- (2022)
Externí odkaz:
https://doaj.org/article/c38eda3c9e1d49fdba3db1c108efeeef
Autor:
Xingming Wang, Lijia Chang, Xiayun Wan, Yunfei Tan, Youge Qu, Jiajing Shan, Yong Yang, Li Ma, Kenji Hashimoto
Publikováno v:
Neurobiology of Disease, Vol 165, Iss , Pp 105635- (2022)
Multiple sclerosis (MS) is the most common demyelinating disease that attacks the central nervous system. We recently reported that the new antidepressant (R)-ketamine could ameliorate the disease progression in experimental autoimmune encephalomyeli
Externí odkaz:
https://doaj.org/article/468c6c555f52459889da29ed2b1ed592
Autor:
Xiayun Wan, Yuko Fujita, Lijia Chang, Yan Wei, Li Ma, Gerile Wuyun, Yaoyu Pu, Bruce D. Hammock, Kenji Hashimoto
Publikováno v:
Neuropsychopharmacology Reports, Vol 40, Iss 4, Pp 412-416 (2020)
Abstract Aim Although opioids have been used as treatment of neuropathic pain, opioids have abuse potential in humans. Since soluble epoxide hydrolase (sEH) in the metabolism of polyunsaturated fatty acids plays a key role in the pain, sEH inhibitors
Externí odkaz:
https://doaj.org/article/c542fbf57fca414c96c6941b88ea34f5