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Akademický článek

Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)

The vast majority of BRCA1-driven breast cancers derive from luminal progenitor cells but the mechanisms of this lineage specificity are unclear. Here the authors show that dangerous accumulation of DNA-RNA hybrid structures due to RNA polymerase II

Externí odkaz: https://doaj.org/article/38cac16b041a40679c30545eb63c3763

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Akademický článek

Correction: Author Correction: Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)

Nature Communications 8: Article number: 15908 (2017); Published 26 June 2017; Updated 30 March 2018 The original version of this Article omitted the following from the Acknowledgements: ‘The work was also supported by a grant to Y.H. from the Canc

Externí odkaz: https://doaj.org/article/fa3634db093c474589df2df1375d07a4

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Akademický článek

Translational Initiation at a Non-AUG Start Codon for Human and Mouse Negative Elongation Factor-B.

Autor: Haihui Pan, Xiayan Zhao, Xiaowen Zhang, Mohamed Abouelsoud, Jianlong Sun, Craig April, Asma Amleh, Jian-Bing Fan, Yanfen Hu, Rong Li

Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0127422 (2015)

Negative elongation factor (NELF), a four-subunit protein complex in metazoan, plays an important role in regulating promoter-proximal pausing of RNA polymerase II (RNAPII). Genetic studies demonstrate that the B subunit of mouse NELF (NELF-B) is cri

Externí odkaz: https://doaj.org/article/37bf9d3504214efb8b60d47f553888e1

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Insights into Capacity Fading Mechanism and Coating Modification of High-Nickel Cathodes in Lithium-Ion Batteries

Autor: Hexin Liu, Xiayan Zhao, Yongjia Xie, Shuting Luo, Zhenyu Wang, Lingyun Zhu, Xing Zhang

Publikováno v: ACS applied materialsinterfaces. 14(50)

Developments in electric vehicles and mobile electronic devices are promoting the demand for lithium-ion batteries with higher capacity and longer lifetime. The performances of lithium-ion batteries are crucially affected by cathode materials, among

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880a4b2f791fadba693d6899b04ff90b
https://pubmed.ncbi.nlm.nih.gov/36503239

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High fibrinogen-albumin ratio index (FARI) predicts poor survival in head and neck squamous cell carcinoma patients treated with surgical resection

Autor: Sisi Wang, Yuhua Feng, Yangchun Xie, Xiayan Zhao, Jinan Ma, Xianling Liu, Chunhong Hu, Tao Hou

Publikováno v: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 279(9)

The aim of the present study was to investigate the predictive value of the fibrinogen/albumin ratio index (FARI), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) on the prognosis of patients with operable head and neck s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c358ebabc48dc93911b4be4af82d76
https://pubmed.ncbi.nlm.nih.gov/35462579

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High fibrinogen-albumin ratio index predicts poor prognosis for lung adenocarcinoma patients undergoing epidermal growth factor receptor-tyrosine kinase inhibitor treatments

Autor: Chunhong Hu, Liu Xianling, Na Zhang, Haixia Zhang, Ping Liu, Xiayan Zhao, Jin’an Ma, Tao Hou

Publikováno v: Medicine

Epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKIs) have become the preferred therapy as first-line treatment of non-small cell lung cancer patients harboring sensitizing EGFR mutations. However, the prognostic indicators are limit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa559af89546c834753d03769483d41
https://pubmed.ncbi.nlm.nih.gov/33181687

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BRCA1-associated R-loop affects transcription and differentiation in breast luminal epithelial cells

Autor: Howard T. Wang, Rong Li, Ismail Jatoi, Yanfen Hu, Andrew Brenner, Xiaowen Zhang, Jingwei Li, Xiayan Zhao, Jerry Chen, Huai-Chin Chiang

Publikováno v: Nucleic Acids Research

BRCA1-associated basal-like breast cancer originates from luminal progenitor cells. Breast epithelial cells from cancer-free BRCA1 mutation carriers are defective in luminal differentiation. However, how BRCA1 deficiency leads to lineage-specific dif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7886d55958bc1f17ac6e5fa7ff37b16
https://pubmed.ncbi.nlm.nih.gov/30982901

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Structure and properties of (1−x)[(K0.5Na0.5)NbO3–LiSbO3]– xBiFe0.8Co0.2O3 lead-free piezoelectric ceramics

Autor: Xiayan Zhao, Xia Zhai, Hua Wang, Ling Yang, Jiwen Xu

Publikováno v: Bulletin of Materials Science. 39:743-747

Lead-free piezoelectric ceramics (1 − x)[0.95(K0.5Na0.5)NbO3–0.05LiSbO3]–xBiFe0.8Co0.2O3(KNN–LS–xBFC) were prepared by a conventional sintering technique. The effect of BFC content on the structure, piezoelectric and electrical properties o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e599fa0ad9e9f26f3a0c71fdfd63061
https://doi.org/10.1007/s12034-016-1191-1

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Influence on structure and properties of CuO addition to KNN–LS–BF piezoelectric ceramics

Autor: Xia Zhai, Ling Yang, Jiwen Xu, Xiayan Zhao, Hua Wang

Publikováno v: Journal of Materials Science: Materials in Electronics. 27:5016-5019

(1 − x)[0.98(0.95Na0.5K0.5NbO3–0.05LiSbO3)–0.02BiFeO3]–xmol%CuO (KNN–LS–BF–xCuO) lead-free piezoelectric ceramics have been synthesized by the conventional solid-state reaction process. It is found that the addition of CuO has not chang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84ec8a60dee6beb80e2c85ccfe406ef3
https://doi.org/10.1007/s10854-016-4388-6

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Abstract CT266: Safety and efficacy of nimotuzumab in combination with chemotherapy in patients with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC): A phase II study

Autor: Yan He, Chunhong Hu, Ping Liu, Tao Hou, Xiayan Zhao, Min Lu

Publikováno v: Cancer Research. 80:CT266-CT266

Introduction: The prognosis od R/M HNSCC patients is poor and the cisplatin-based chemotherapy is currently the standard care of those patients. Nimotuzumab is a humanized EGFR monoclonal antibody which has been proven to be effective in locally-adva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c55ad42a9086918319c0c81c252bad65
https://doi.org/10.1158/1538-7445.am2020-ct266

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