Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Xiatian Chen"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Cancers, especially malignant tumors, contribute to high global mortality rates, resulting in great economic burden to society. Many factors are associated with cancer pathogenesis, including vascular endothelial growth factor-A (VEGFA) and circular
Externí odkaz:
https://doaj.org/article/0236c8bf022648519b61e56f14f85d37
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Gastric cancer (GC) is a malignant cancer that reduces life expectancy worldwide. Although treatment strategies have improved, patients with GC still have poor prognoses. Hence, it is necessary to understand the molecular mechanisms of GC and to find
Externí odkaz:
https://doaj.org/article/b2aa00476a2f460bbd76c95f000e446d
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 220-236 (2021)
Cardiovascular disease (CVD) is one of the most important diseases endangering human life. The pathogenesis of CVDs is complex. Pyroptosis, which differs from traditional apoptosis and necrosis, is characterized by cell swelling until membrane ruptur
Externí odkaz:
https://doaj.org/article/c8321d9928d94b36aac7de09c3913bc6
Autor:
Lynn Htet Htet Aung, Xiatian Chen, Juan Carlos Cueva Jumbo, Zhe Li, Shao-ying Wang, Cheng Zhao, Ziqian Liu, Yin Wang, Peifeng Li
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 638-651 (2021)
Doxorubicin (DOX)-induced cardiotoxicity has been one of the major limitations for its clinical use. Although extensive studies have been conducted to decipher the molecular mechanisms underlying DOX cardiotoxicity, no effective preventive or therape
Externí odkaz:
https://doaj.org/article/27701e1efd034180af82a177ee555915
Autor:
Xiatian Chen, Chengzhen Shi, Yin Wang, Hua Yu, Yu Zhang, Jiaxuan Zhang, Peifeng Li, Jinning Gao
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Patients with diabetes have severe vascular complications, such as diabetic nephropathy, diabetic retinopathy, cardiovascular disease, and neuropathy. Devastating vascular complications lead to increased mortality, blindness, kidney failure, and decr
Externí odkaz:
https://doaj.org/article/1ce0c80306be4eb495098a247b98ab1c
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 101-118 (2021)
Cardiovascular diseases (CVDs) remain the world’s leading cause of death. Cardiomyocyte autophagy helps maintain normal metabolism and functioning of the heart. Importantly, mounting evidence has revealed that autophagy plays a dual role in CVD pat
Externí odkaz:
https://doaj.org/article/447205857db74afa8a0d0b7858cec913
Autor:
Xiatian Chen, Hua Yu, Zhe Li, Wei Ye, Ziqian Liu, Jinning Gao, Yin Wang, Xin Li, Lei Zhang, Natalia Alenina, Michael Bader, Hongyan Ding, Peifeng Li, Lynn Htet Htet Aung
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Excessive production of free radicals can induce cellular damage, which is associated with many diseases. RNA is more susceptible to oxidative damage than DNA due to its single-stranded structure, and lack of protective proteins. Yet, oxidative damag
Externí odkaz:
https://doaj.org/article/0804ccc49db7454c828aef88c6183f8f
Autor:
Zhe Li, Xiatian Chen, Ziqian Liu, Wei Ye, Ling Li, Lili Qian, Hongyan Ding, Peifeng Li, Lynn Htet Htet Aung
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Compared with the research on DNA damage, there are fewer studies on RNA damage, and the damage mechanism remains mostly unknown. Recent studies have shown that RNA is more vulnerable to damage than DNA when the cells are exposed to endogenous and ex
Externí odkaz:
https://doaj.org/article/faacfb6d6e60418b9d56cec126ffce86
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 5022 (2020)
In the history of nucleic acid research, DNA has always been the main research focus. After the sketch of the human genome was completed in 2000, RNA has been started to gain more attention due to its abundancies in the cell and its essential role in
Externí odkaz:
https://doaj.org/article/214234bee81b40cf9027b3fdf93a3dc1
Publikováno v:
Journal of Microbiology and Biotechnology. 32:1226-1233