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pro vyhledávání: '"Xiaozhu Chu"'
Autor:
Xiaozhu Chu
Publikováno v:
Dentistry 3000, Vol 5, Iss 1, Pp 59-64 (2017)
Background: Oral candidiasis is by far the most common oral fungal infection in humans. It is caused by the fungal organism Candida albicans. When the host is debilitated by other diseases and conditions, C. albicans, which is usually a part of the n
Externí odkaz:
https://doaj.org/article/c1043b408f274be2abec214d68be5ed7
Publikováno v:
Supramolecular Chemistry. 21:316-323
The development of oligonucleotide-linked small molecules for protein recognition is a worthy undertaking with potential applications in drug discovery and diagnostics. Although the ground work for this novel approach to protein recognition is still
Autor:
Xiaozhu Chu, Cooper H. Battle, Janarthanan Jayawickramarajah, Gyan H. Aryal, Madhusoodanan Mottamal, Nan Zhang
Publikováno v:
Bioconjugate chemistry. 26(8)
In order to tackle the issue of systemic toxicity in chemotherapy, there is a need to develop novel mechanisms for the activation of protein inhibitors using biomarkers over-expressed in cancer cells. Many current strategies focus on using cancer ass
Photonic DNA nanostructures are typically prepared by the assembly of multiple sequences of long DNA strands that are conjugated covalently to various dye molecules. Herein we introduce a non-covalent method for the construction of porphyrin-containi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216eb65a8f90d0073f8b52479eb3fff2
https://europepmc.org/articles/PMC3826913/
https://europepmc.org/articles/PMC3826913/
Supramolecular chemists continuously take inspiration from complex biological systems to develop functional molecules involved in molecular recognition and self-assembly. In this regard, ‘smart’ synthetic molecules that emulate allosteric protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d0e3eb2b0c27823606764812760253
https://europepmc.org/articles/PMC3810975/
https://europepmc.org/articles/PMC3810975/
Publikováno v:
Journal of the American Chemical Society. 130:14950-14951
In this communication, we disclose a generalizable strategy for developing agents with regulable protein-binding ability. In particular, a responsive DNA-small molecule chimera (DC) 1 consisting of two synthetic protein-binding arms and a core oligon