Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Xiaoyun Xiao"'
Autor:
Yixia Liang, Rong Lei, Jiabao Tan, Junyue Fang, Lin Yu, Shiyu Tan, Yan Nie, Qiongchao Jiang, Xiaoyun Xiao, Phei Er Saw
Publikováno v:
BIO Integration, Vol 4, Iss 4, Pp 170-179 (2023)
Antibody-drug conjugates (ADCs) have the following advantages: target specificity; wide therapeutic index; and prolonged circulation half-life. A key limitation of ADCs, however, is the large size (~150 kDa), which markedly slows diffusion through th
Externí odkaz:
https://doaj.org/article/cef41e8a3484474eaa4adac03c8ed53b
Autor:
Yanni Xu, Yunting Zeng, Xiaoyun Xiao, Hejun Liu, Boyang Zhou, Baoming Luo, Phei Er Saw, Qiongchao Jiang
Publikováno v:
BIO Integration, Vol 4, Iss 3, Pp 114-124 (2023)
Breast cancer is a highly heterogeneous disease lacking prognostic markers. Tumor-associated macrophages (TAMs) in the tumor microenvironment are associated with distant metastasis as well as poorer outcomes in breast cancer. Therefore, monitoring TA
Externí odkaz:
https://doaj.org/article/5e21fcbb784d4de8aef27f6b24d44d72
Autor:
Junyue Fang, Li Lin, Yuan Cao, Jiabao Tan, Yixia Liang, Xiaoyun Xiao, Nengtai Ouyang, Phei Er Saw, Wei Yang
Publikováno v:
BIO Integration, Vol 5, Iss 1 (2024)
CD24, also known as heat-stable protein, is a highly glycosylated glycosylphosphatidylinositol junction membrane protein. CD24 specifically binds sialic-acid-binding Ig-like lectin 10 (Siglec10) on macrophages and serves as a “don’t eat me” sig
Externí odkaz:
https://doaj.org/article/d75ffbff124544f9bfdee76eeed896e1
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 774-793 (2023)
Long non-coding RNAs (lncRNAs) are a class of RNA transcripts more than 200 nucleotides in length that play crucial roles in cancer development and progression. With the rapid development of high-throughput sequencing technology, a considerable numbe
Externí odkaz:
https://doaj.org/article/a8641ea48b8c4b67a067d70d83c73770
Autor:
Shishi He, Xiaoyun Xiao, Rong Lei, Jiewen Chen, Hongyan Huang, Ailifeire Yilihamu, Mingyan Guo, Cui Tan, Xun Li, Zilin Zhuang, Phei Er Saw, Yan Nie
Publikováno v:
BIO Integration, Vol 4, Iss 1, Pp 7-17 (2023)
Breast phyllodes tumors (PTs) are biphasic, with epithelial and stromal components. Although the PT incidence is low (approximately 1% of all breast tumors), its clinical outcomes are unpredictable, and malignant PTs often progress rapidly. No effect
Externí odkaz:
https://doaj.org/article/d24dc0a3acdb4a66b17a7ce19e2882e8
Autor:
Xinwei Liu, Yingying Ye, Liling Zhu, Xiaoyun Xiao, Boxuan Zhou, Yuanting Gu, Hang Si, Huixin Liang, Mingzhu Liu, Jiaqian Li, Qiongchao Jiang, Jiang Li, Shubin Yu, Ruiying Ma, Shicheng Su, Jian-You Liao, Qiyi Zhao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Stromal cells in the tumour microenvironment are reported to regulate cancer stemness via biomechanical signals. Here the authors show that TAZ activated by biomechanical cues enhanced cancer stem cell properties via phase separation with Nanog.
Externí odkaz:
https://doaj.org/article/647b8e9e8f1e465d8e7465b5fd2e1721
Autor:
Dinghong Yang, Xiaoyun Xiao, Haohu Wang, Huan Wu, Wei Qin, Xiaofeng Guan, Qiongchao Jiang, Baoming Luo
Publikováno v:
BIO Integration, Vol 3, Iss 2, Pp 61-70 (2022)
Background: Benign or malignant breast lesions with typical ultrasonic characteristics could be easily and correctly diagnosed with two-dimensional ultrasound (2D US). However, diagnosis of atypical lesions remains a challenge. Most atypical lesions
Externí odkaz:
https://doaj.org/article/ba830f0614454a39961f10ee5ef511bf
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/23d4029b3be14789871a0e6548947e49
Autor:
Qiongchao Jiang, Yunting Zeng, Yanni Xu, Xiaoyun Xiao, Hejun Liu, Boyang Zhou, Yao Kong, Phei Er Saw, Baoming Luo
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Though radiofrequency ablation (RFA) is considered to be an effective treatment for hepatocellular carcinoma (HCC), but more than 30% of patients may suffer insufficient RFA (IRFA), which can promote more aggressive of the residual tumor. One possibl
Externí odkaz:
https://doaj.org/article/61dbee3602a04818ad3091f69da3886b
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
Background. RNA helicases have various essential functions in basically all aspects of RNA metabolism, not only unwinding RNA but also disturbing the interaction of RNA with proteins. Recently, RNA helicases have been considered potential targets in
Externí odkaz:
https://doaj.org/article/ca5a0e5c78704ad9846a9152465b6324