Výsledky vyhledávání - "Xiaoyun Ning"

Identification of N- and C-3-Modified Laudanosoline Derivatives as Novel Influenza PAN Endonuclease Inhibitors

Autor: Yixian Liao, Yilu Ye, Mingjian Liu, Zhihao Liu, Jinshen Wang, Baixi Li, Lijian Huo, Yilian Zhuang, Liye Chen, Jianxin Chen, Yongfeng Gao, Xiaoyun Ning, Sumei Li, Shuwen Liu, Gaopeng Song

Publikováno v: Journal of Medicinal Chemistry. 66:188-219

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::728cb4ec1b20f219e61fa5889ea8033b
https://doi.org/10.1021/acs.jmedchem.2c00857

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Discovery and structural optimization of 3-O-β-Chacotriosyl betulonic acid saponins as potent fusion inhibitors of Omicron virus infections

Autor: Mingjian, Liu, Jinshen, Wang, Xin, Wan, Baixi, Li, Mingming, Guan, Xiaoyun, Ning, Xiaojie, Hu, Sumei, Li, Shuwen, Liu, Gaopeng, Song

Publikováno v: Bioorganic Chemistry. 131:106316

The recent global Omicron epidemics underscore the great need for the development of small molecule therapeutics with appropriate mechanisms. The trimeric spike protein (S) of SARS-CoV-2 plays a pivotal role in mediating viral entry into host cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e964b0cb2e81d46a36cc07c52d30f2
https://doi.org/10.1016/j.bioorg.2022.106316

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Periodical

Findings from South China Agricultural University Update Knowledge of COVID-19 (Discovery and Structural Optimization of 3-o-beta-chacotriosyl Betulonic Acid Saponins As Potent Fusion Inhibitors of Omicron Virus Infections).

Publikováno v: NewsRx COVID-19 Weekly; 2/12/2023, p258-258, 1p

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