Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Xiaoyun Ji"'
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Sepsis-caused multi-organ failure remains the major cause of morbidity and mortality in intensive care units with limited therapeutics. Nicotinamide mononucleotide (NMN), a precursor of nicotinamide adenine dinucleotide (NAD+), ha
Externí odkaz:
https://doaj.org/article/87b2dd02990d40518d910bef1d5c3eeb
Autor:
Hangtian Guo, Yixuan Yang, Tiantian Zhao, Yuchi Lu, Yan Gao, Tinghan Li, Hang Xiao, Xiaoyu Chu, Le Zheng, Wanting Li, Hao Cheng, Haibin Huang, Yang Liu, Yang Lou, Henry C. Nguyen, Chao Wu, Yuxin Chen, Haitao Yang, Xiaoyun Ji
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
The molecular mechanism of broad-spectrum neutralization of a rabbit monoclonal antibody 1H1 against Omicron sublineages is revealed by cryo-EM.
Externí odkaz:
https://doaj.org/article/5f181490fbe04e35828b3c8b432fc39c
Autor:
Yuxin Chen, Lin Chen, Shengxia Yin, Yue Tao, Liguo Zhu, Xin Tong, Minxin Mao, Ming Li, Yawen Wan, Jun Ni, Xiaoyun Ji, Xianchi Dong, Jie Li, Rui Huang, Ya Shen, Han Shen, Changjun Bao, Chao Wu
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1524-1536 (2022)
The waning humoral immunity and emerging contagious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants resulted in the necessity of the booster vaccination of coronavirus disease 2019 (COVID-19). The inactivated vaccine, CoronaVac,
Externí odkaz:
https://doaj.org/article/abb863651da64bb6b65af6dc42888a5b
Autor:
Ting Cao, Rui Ni, Weimin Ding, Xiaoyun Ji, Lan Li, Guangneng Liao, Yanrong Lu, Guo-Chang Fan, Zhuxu Zhang, Tianqing Peng
Publikováno v:
Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-15 (2022)
Abstract Background Cardiomyocyte death contributes to cardiac pathology of diabetes. Studies have shown that the RIPK3/MLKL necroptosis signaling is activated in diabetic hearts. Deletion of RIPK3 was reported to attenuate myocardial injury and hear
Externí odkaz:
https://doaj.org/article/ada2e978445144918d77f081a979c81e
Autor:
Haofeng Wang, Yunjie Xiao, Xia Chen, Mengwen Zhang, Guangxin Sun, Feng Wang, Lin Wang, Hanxiao Zhang, Xiaoyu Zhang, Xin Yang, Wenling Li, Yi Wei, Deqiang Yao, Bing Zhang, Jun Li, Wen Cui, Fenghua Wang, Cheng Chen, Wei Shen, Dan Su, Fang Bai, Jinhai Huang, Sheng Ye, Lei Zhang, Xiaoyun Ji, Wei Wang, Zefang Wang, Mark Hochstrasser, Haitao Yang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Wolbachia induced cytoplasmic incompatibility (CI) is caused by linked pairs of genes named cifA and cifB. Here, authors show that the residues at interfaces of the CidA-CidB complex is crucial for their binding and contribute to the diversity of CI.
Externí odkaz:
https://doaj.org/article/5351223854f14543a1a92277551c3456
Autor:
Shiqing Ye, Liang Wang, Shengkai Li, Qingyong Ding, Yu Wang, Xinxin Wan, Xiaoyun Ji, Yongliang Lou, Xiang Li
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
IntroductionRecent studies have provided insights into the important contribution of gut microbiota in the development of Pulmonary Tuberculosis (PTB). As a chronic consumptive infectious disease, PTB involves many pathological characteristics. At pr
Externí odkaz:
https://doaj.org/article/ffc91ff8be4245f3a76f061bb1a80d0c
Autor:
Tingting Li, Xiaojian Han, Chenjian Gu, Hangtian Guo, Huajun Zhang, Yingming Wang, Chao Hu, Kai Wang, Fengjiang Liu, Feiyang Luo, Yanan Zhang, Jie Hu, Wang Wang, Shenglong Li, Yanan Hao, Meiying Shen, Jingjing Huang, Yingyi Long, Shuyi Song, Ruixin Wu, Song Mu, Qian Chen, Fengxia Gao, Jianwei Wang, Shunhua Long, Luo Li, Yang Wu, Yan Gao, Wei Xu, Xia Cai, Di Qu, Zherui Zhang, Hongqing Zhang, Na Li, Qingzhu Gao, Guiji Zhang, Changlong He, Wei Wang, Xiaoyun Ji, Ni Tang, Zhenghong Yuan, Youhua Xie, Haitao Yang, Bo Zhang, Ailong Huang, Aishun Jin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Neutralizing antibodies are currently one versatile strategy to treat SARS-CoV-2 infection. Here, Li et al. characterize three monoclonal antibodies neutralizing authentic virus infection in vitro and in vivo by targeting the receptor binding domain
Externí odkaz:
https://doaj.org/article/7abf996e0f9d4da6b7b08529e0aeb206
Autor:
Hangtian Guo, Yan Gao, Tinghan Li, Tingting Li, Yuchi Lu, Le Zheng, Yue Liu, Tingting Yang, Feiyang Luo, Shuyi Song, Wei Wang, Xiuna Yang, Henry C. Nguyen, Hongkai Zhang, Ailong Huang, Aishun Jin, Haitao Yang, Zihe Rao, Xiaoyun Ji
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110770- (2022)
Summary: The emergence of the SARS-CoV-2 Omicron variant is dominant in many countries worldwide. The high number of spike mutations is responsible for the broad immune evasion from existing vaccines and antibody drugs. To understand this, we first p
Externí odkaz:
https://doaj.org/article/0243c363c71647739e7b47f3ef93ef6e
Autor:
Meijing Wang, Tinghan Li, Zijun Ouyang, Kai Tang, Yuyu Zhu, Chenglin Song, Haiyan Sun, Bin Yu, Xiaoyun Ji, Yang Sun
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104009- (2022)
Summary: SHP2 is the first oncogenic tyrosine phosphatase encoded by PTPN11, which plays a significant regulatory role in cancer and inflammation-related diseases. Although SHP2 allosteric inhibitors have been used in phase I/II clinical trials for s
Externí odkaz:
https://doaj.org/article/f590356640924cf5a34c0e6a0e184f03
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Interleukin (IL)-9 belongs to the IL-2Rγc chain family and is a multifunctional cytokine that can regulate the function of many kinds of cells. It was originally identified as a growth factor of T cells and mast cells. In previous studies,
Externí odkaz:
https://doaj.org/article/be29aaabb6f74bfebd3483aae2495b89