Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Xiaoye Fan"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115047- (2023)
Epidemiologic studies have shown that fine particulate matter 2.5 (PM2.5) exaggerates airway inflammation associated with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Daphnetin (Daph) is a natural compound with a variety of b
Externí odkaz:
https://doaj.org/article/6dc4762f98814a6588296f50a5e52a26
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115097- (2023)
Objective: Acetaminophen (APAP) is one of the world's popular and safe painkillers, and overdose can cause severe liver damage and even acute liver failure. The effect and mechanism of the xanthohumol on acetaminophen-induced hepatotoxicity remains u
Externí odkaz:
https://doaj.org/article/fc5d301805464f1cbab655d41323176f
Publikováno v:
Redox Biology, Vol 59, Iss , Pp 102587- (2023)
The increasing abundance of fine particulate matter (PM2.5) in the environment has increased susceptibility to acute exacerbation of COPD (AECOPD). During PM2.5 exposure, excessive reactive oxygen species (ROS) production triggers a redox imbalance,
Externí odkaz:
https://doaj.org/article/01c9a2c5070c4aa4b40a6e5c2a146557
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Many natural flavonoids can activate nuclear factor erythroid 2-related factor 2 (Nrf2), which is pivotal for alleviating various diseases related to inflammation and oxidative stress, including pleurisy. Amentoflavone (AMF), a biflavonoid extracted
Externí odkaz:
https://doaj.org/article/ef73050dfdad407f9e522ae46937500b
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Cisplatin (CDDP) is a widely used drug for cancer treatment that exhibits major side effects in normal tissues, such as nephrotoxicity in kidneys. The Nrf2 signaling pathway, a regulator of mitochondrial dysfunction, oxidative stress and inflammation
Externí odkaz:
https://doaj.org/article/a66e6dafc5ae4dbabf7da32c48449e02
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Cisplatin (CDDP) is a widely used chemotherapeutic agent for various solid tumors, but its severe side effects, particularly nephrotoxicity, limit its clinical application. Isoorientin (Iso) is a flavonoid-like compound known to have antioxidant effe
Externí odkaz:
https://doaj.org/article/8f828c80ec1241ec8cba2e26304cd3cd
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 5, Pp 1943-1958 (2018)
Background/Aims: Pterostilbene (Pts), a natural dimethylated analog of resveratrol from blueberries, exerts antioxidative and anti-apoptotic effects in various diseases. This study aims to investigate the protective effects and mechanism of Pts again
Externí odkaz:
https://doaj.org/article/d9a9f3c1448647029693ba4ef2cff7cd
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Cisplatin is a chemotherapy drug that is often used in clinical practice, but its frequent use often leads to nephrotoxicity. Therefore, we urgently need a drug that reduces the nephrotoxicity induced by cisplatin. Farrerol reportedly has antioxidant
Externí odkaz:
https://doaj.org/article/a5da8db1e09d46fb8844712310f23ea4
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
AMPK-mediated autophagy and Akt/mTOR pathways play important roles in current cancer treatments. Oridonin (Ori), an ent-kaurane diterpenoid isolated from Isodon rubescens, exerts extensive anti-tumor potential and controversial effects on autophagy.
Externí odkaz:
https://doaj.org/article/9aed998e40c8418f9bb251f59c24685d
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Oxidative stress has been highlighted as therapeutic targets for acetaminophen (APAP)-induced hepatotoxicity. Isoorientin (Iso), a well-known flavonoid-like compound, has been shown to have antioxidant potential. However, the effect of Iso on APAP-in
Externí odkaz:
https://doaj.org/article/b8cb41d8a65f424f8364d921072bc40b