Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Xiaoxue Ruan"'
Autor:
Huiti Li, Yali Liu, Zian Xue, Li Zhang, Xiaoxue Ruan, Jintong Yang, Zhongjiao Fan, Hongfang Zhao, Yu Cao, Guoqiang Chen, Ying Xu, Lu Zhou
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Hypoxia inducible factor‐1α (HIF‐1α) plays a critical role in cellular adaptation to hypoxia and it is a potential therapeutic target for anti‐cancer drugs. Applying high‐throughput screening, here it is found that HI‐101, a smal
Externí odkaz:
https://doaj.org/article/d424d97313b04e23aace14a1d0dad293
Publikováno v:
Engineering Reports, Vol 5, Iss 2, Pp n/a-n/a (2023)
Abstract Arch‐chord coupled anti‐sliding structure is a new type of anti‐sliding structure composed of multiple single piles in a specific form. The coupling effect of pile and soil is the most important key point. In this article, the factors
Externí odkaz:
https://doaj.org/article/19a423ca6a70493f861067f4157268b1
Autor:
Jiashen Zhou, Lin Zhang, Liping Zeng, Lu Yu, Yuanyuan Duan, Siqi Shen, Jingyan Hu, Pan Zhang, Wenyan Song, Xiaoxue Ruan, Jing Jiang, Yinan Zhang, Lu Zhou, Jia Jia, Xudong Hang, Changlin Tian, Houwen Lin, Hong-Zhuan Chen, John E. Cronan, Hongkai Bi, Liang Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Helicobacter pylori FabX, a dehydrogenase/isomerase flavoprotein, is required for unsaturated fatty acid synthesis. Here, the authors characterize FabX substrate recognition and catalytic mechanism, and reveal that it contains an atypical [4Fe-4S] cl
Externí odkaz:
https://doaj.org/article/ff98c86182784a2baf66ddf02f8bcbf9
Publikováno v:
Engineering Reports, Vol 4, Iss 2, Pp n/a-n/a (2022)
Abstract With the increase in the mileage of high‐speed railways around the world, subgrade problems related to the same have been emerging in large numbers. In view of the shortcomings of slow construction speed and large disturbance caused by con
Externí odkaz:
https://doaj.org/article/63e08591510e4626a1934a46e8e5b667
Publikováno v:
Geofluids, Vol 2022 (2022)
Arch-chord-coupled antisliding structure is a new type of structure composed of multiple small-diameter piles for strengthening small- and medium-sized landslides, especially suitable for the reinforcement of slopes that are sensitive to deformation.
Externí odkaz:
https://doaj.org/article/019b7f398a494e81948c78bbb938a3ab
Publikováno v:
Engineering Reports. 5
The slope of an open cut tunnel is located above the exit of the Leijia tunnel on the Changgan high-speed railway. During the excavation of the open cut tunnel foundation pit, the slope slipped twice, a large landslide of 92500 m³ formed. The landsl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ee388ecedf475510a819aa5795976ea
https://doi.org/10.21203/rs.3.rs-1210915/v1
https://doi.org/10.21203/rs.3.rs-1210915/v1
Autor:
Houwen Lin, Siqi Shen, John E. Cronan, Hong-Zhuan Chen, Jingyan Hu, Hongkai Bi, Yuanyuan Duan, Xudong Hang, Wenyan Song, Xiaoxue Ruan, Pan Zhang, Jing Jiang, Lu Zhou, Lu Yu, Yinan Zhang, Changlin Tian, Liping Zeng, Lin Zhang, Liang Zhang, Jiashen Zhou, Jia Jia
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Unsaturated fatty acids (UFAs) are essential for functional membrane phospholipids in most bacteria. The bifunctional dehydrogenase/isomerase FabX is an essential UFA biosynthesis enzyme in the widespread human pathogen Helicobacter pylori, a bacteri
Publikováno v:
Engineering Reports, Vol 4, Iss 2, Pp n/a-n/a (2022)
With the increase in the mileage of high‐speed railways around the world, subgrade problems related to the same have been emerging in large numbers. In view of the shortcomings of slow construction speed and large disturbance caused by conventional
Autor:
Xiaodan Zhang, Wei Lu, Xiaoxue Ruan, Zhu Chen, Penghui Wang, Qian Wang, Chenghong Peng, Qian Zhan, Deyong Ye, Luhua Lai, Xiongxiong Lu, Hongwei Li, Lulu Jiang, Chenlei Wen, Qingbing Wang, Min-Min Shi, Xinjing Wang, Xiaomei Tang, Yuting Dai, Sai-Juan Chen, Yuan Fang, Xiao-Qiang Xiang, Huiti Li, Min Li, Lu Zhou, Jinyan Huang, Yanhui Xu, Jing Chen, Baiyong Shen, Xun Sun, Ke Huang, Liwen Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 116:23264-23273
Glycolytic enzyme phosphoglycerate mutase 1 (PGAM1) plays a critical role in cancer metabolism by coordinating glycolysis and biosynthesis. A well-validated PGAM1 inhibitor, however, has not been reported for treating pancreatic ductal adenocarcinoma