Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Xiaoxing Luo"'
Autor:
Zhou Chen, Yue Hu, Xinggang Mao, Dan Nie, Hui Zhao, Zheng Hou, Mingkai Li, Jingru Meng, Xiaoxing Luo, Xiaoyan Xue
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Outbreaks of infection due to multidrug-resistant (MDR) bacteria, especially Gram-negative bacteria, have become a global health issue in both hospitals and communities. Antisense oligonucleotides (ASOs) based therapeutics hold a
Externí odkaz:
https://doaj.org/article/f3330b908a2d460380d0b08df7e22cd6
Autor:
Yue Hu, Zhou Chen, Xinggang Mao, Mingkai Li, Zheng Hou, Jingru Meng, Xiaoxing Luo, Xiaoyan Xue
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background Antisense oligonucleotides (ASOs) based technology is considered a potential strategy against antibiotic-resistant bacteria; however, a major obstacle to the application of ASOs is how to deliver them into bacteria effectively. DN
Externí odkaz:
https://doaj.org/article/e598f78244af4240a2736b033808e648
Autor:
Shan Su, Pengshuo Yin, Jing Li, Guanghui Chen, Yikun Wang, Di Qu, Zhoupeng Li, Xiaoyan Xue, Xiaoxing Luo, Mingkai Li
Publikováno v:
Journal of Infection and Public Health, Vol 13, Iss 5, Pp 791-799 (2020)
Background: The development of bacterial biofilm can cause severe chronic infections and antibiotic resistance. Therefore, it poses a significant threat to public health. Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa) ar
Externí odkaz:
https://doaj.org/article/511a3e30dd8548efa3b842f50c5c5651
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-8 (2020)
Abstract Acinetobacter baumannii (A. baumannii) is an important opportunistic pathogen causing serious nosocomial infections, which is considered as the most threatening Gram-negative bacteria (GNB). Outer membrane protein A (OmpA), a major component
Externí odkaz:
https://doaj.org/article/8e861c15ee7840bba18c44740330194f
Autor:
Bo Ma, Chao Fang, Linshan Lu, Mingzhi Wang, Xiaoyan Xue, Ying Zhou, Mingkai Li, Yue Hu, Xiaoxing Luo, Zheng Hou
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The NDM-1 metallo-β-lactamase confers resistance to β-lactam antibiotics. Here, the authors show that the antimicrobial peptide thanatin is active against NDM-1-producing bacteria through a dual mechanism of action consisting of disruption of outer
Externí odkaz:
https://doaj.org/article/5264630a22df4ed9ae5b7ee92c052341
Publikováno v:
Bio-Protocol, Vol 10, Iss 5 (2020)
The emergence and rapid spread of multidrug resistance in bacteria have led to the urgent need for novel antibacterial agents. Membrane permeabilization is the mechanism for many antibacterial molecules that are being developed against gram-negative
Externí odkaz:
https://doaj.org/article/16776fa8fd8e4b9282a581a5e6bc5fc7
Autor:
Ning Wang, Jian Gao, Min Jia, Xue Ma, Zhanxiang Lei, Fei Da, Fei Yan, Huinan Zhang, Ying Zhou, Mingkai Li, Gonghao He, Jingru Meng, Xiaoxing Luo
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 5, Pp 1696-1714 (2017)
Background/Aims: The synthesis and degradation processes involved in bone remodeling are critically regulated by osteoblasts and osteoclasts. The GLP-1 receptor agonist Exendin-4 is beneficial for osteoblast differentiation and increases the number o
Externí odkaz:
https://doaj.org/article/e411ddf0f0874be3a803d1eace8bd660
Publikováno v:
Drug Delivery, Vol 24, Iss 1, Pp 1295-1301 (2017)
Nanocarriers of drugs have attracted significant attention to tackle the problems of drug resistance or nucleic acid drug delivery, which can optimize pharmaceutical parameters and enhance the cellular uptake efficiency. Nowadays, DNA nanostructure p
Externí odkaz:
https://doaj.org/article/fbdd613639d646b6b6a98b3a186062e8
Autor:
Jingru Meng, Xue Ma, Ning Wang, Min Jia, Long Bi, Yunying Wang, Mingkai Li, Huinan Zhang, Xiaoyan Xue, Zheng Hou, Ying Zhou, Zhibin Yu, Gonghao He, Xiaoxing Luo
Publikováno v:
Stem Cell Reports, Vol 6, Iss 4, Pp 579-591 (2016)
Glucagon-like peptide 1 (GLP-1) plays an important role in regulating bone remodeling, and GLP-1 receptor agonist shows a positive relationship with osteoblast activity. However, GLP-1 receptor is not found in osteoblast, and the mechanism of GLP-1 r
Externí odkaz:
https://doaj.org/article/0e8bfaaa98634704a959da359d011014
Autor:
Fei Da, Hwang-Soo Joo, Gordon Y. C. Cheung, Amer E. Villaruz, Holger Rohde, Xiaoxing Luo, Michael Otto
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Coagulase-negative staphylococci (CoNS) are important nosocomial pathogens and the leading cause of sepsis. The second most frequently implicated species, after Staphylococcus epidermidis, is Staphylococcus haemolyticus. However, we have a significan
Externí odkaz:
https://doaj.org/article/21bfc1629fa242c88bf0174aed078fb5