Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Xiaoxin Ren"'
Autor:
Hao Wang, R. Alejandro Sica, Gurbakhash Kaur, Phillip M. Galbo, Zhixin Jing, Christopher D. Nishimura, Xiaoxin Ren, Ankit Tanwar, Bijan Etemad-Gilbertson, Britta Will, Deyou Zheng, David Fooksman, Xingxing Zang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Acute myeloid leukemia (AML) is initiated and sustained by a hierarchy of leukemia stem cells (LSCs), and elimination of this cell population is required for curative therapies. Here we show that transmembrane and immunoglobulin domain conta
Externí odkaz:
https://doaj.org/article/a2e33ebf797e44bb8a9fed989423f519
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101818- (2022)
Summary: Human killer cell immunoglobulin-like receptor, three Ig domains and long cytoplasmic tail (KIR3DL3) is expressed on natural killer (NK) cells and is a newly identified inhibitory receptor for B7 family member HERV-H LTR-associating protein
Externí odkaz:
https://doaj.org/article/a23d725b356441379a18bedea1fc54bf
Autor:
Xiaoxin Ren, Mou Peng, Peng Xing, Yao Wei, Phillip M. Galbo Jr., Devin Corrigan, Hao Wang, Yingzhen Su, Xiaoshen Dong, Qizhe Sun, Yixian Li, Xiaoyu Zhang, Winfried Edelmann, Deyou Zheng, Xingxing Zang
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)
Cancer immunotherapy targeting the TIGIT/PVR pathway is currently facing challenges. KIR2DL5, a member of the human killer cell, immunoglobulin-like receptor (KIR) family, has recently been identified as another binding partner for PVR. The biology a
Externí odkaz:
https://doaj.org/article/8658c6903a934daf9b1b1248e348b5f9
Autor:
B. Hilda Ye, Murali Janakiram, Amit Verma, Xingxing Zang, Ulrich Steidl, Seishi Ogawa, Jinghang Zhang, Yiyu Zou, Xiaolei Wei, Boris Bartholdy, Kith Pradhan, Xiaoxin Ren, Keisuke Kataoka, Elise Ishida, Yongqiang Wei, Urvi A. Shah, Yun Mai, Elaine Y. Chung
Supplementary Tables Table S1. List of antibodies used in Western blotting and flow cytometry analyses. Table S2. List of qRT-PCR primers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50130f64d3d184644596cc2cc809fc8f
https://doi.org/10.1158/1078-0432.22469883
https://doi.org/10.1158/1078-0432.22469883
Autor:
B. Hilda Ye, Murali Janakiram, Amit Verma, Xingxing Zang, Ulrich Steidl, Seishi Ogawa, Jinghang Zhang, Yiyu Zou, Xiaolei Wei, Boris Bartholdy, Kith Pradhan, Xiaoxin Ren, Keisuke Kataoka, Elise Ishida, Yongqiang Wei, Urvi A. Shah, Yun Mai, Elaine Y. Chung
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6399b25919577fd75b6d4c3ecbc69b01
https://doi.org/10.1158/1078-0432.22469886.v1
https://doi.org/10.1158/1078-0432.22469886.v1
Autor:
B. Hilda Ye, Murali Janakiram, Amit Verma, Xingxing Zang, Ulrich Steidl, Seishi Ogawa, Jinghang Zhang, Yiyu Zou, Xiaolei Wei, Boris Bartholdy, Kith Pradhan, Xiaoxin Ren, Keisuke Kataoka, Elise Ishida, Yongqiang Wei, Urvi A. Shah, Yun Mai, Elaine Y. Chung
Purpose:To evaluate therapeutic activity of PAK inhibition in ATLL and to characterize the role of PAK isoforms in cell proliferation, survival, and adhesion of ATLL cells in preclinical models.Experimental Design:Frequency and prognostic impact of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e581f9043262dedf4e8b98569bfb34f
https://doi.org/10.1158/1078-0432.c.6527379
https://doi.org/10.1158/1078-0432.c.6527379
Autor:
B. Hilda Ye, Murali Janakiram, Amit Verma, Xingxing Zang, Ulrich Steidl, Seishi Ogawa, Jinghang Zhang, Yiyu Zou, Xiaolei Wei, Boris Bartholdy, Kith Pradhan, Xiaoxin Ren, Keisuke Kataoka, Elise Ishida, Yongqiang Wei, Urvi A. Shah, Yun Mai, Elaine Y. Chung
Supplementary Figures Figure S1. Related to Materials and Methods Immunophenotype and viral gene expression status of the three NA-ATLL cell lines Figure S2. Related to Figure 1. PAK2 amplification pattern in ATLL and expression of PAK isoforms in pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f452204e40c79bf1848af1d4c38789
https://doi.org/10.1158/1078-0432.22469889
https://doi.org/10.1158/1078-0432.22469889
Autor:
McKenna Lamb, Yao Wei, Xiaoxin Ren, Rachel O'Connor, Austin Dulak, Matthew Rausch, Jamie Strand, Bijan Etemad-Gilbertson, Riale Gilligan, Scott Chappel, Tomonari Shigemura, David McDermott, Gordon Freeman, XingXing Zang
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
B. Hilda Ye, Elaine Chung, Xiaoxin Ren, Kith Pradhan, Yanhua Wang, Advaitha Madireddy, Xingxing Zang, Murali Janakiram, R. Alejandro Sica, Amit Verma
Publikováno v:
Blood. 140:8764-8765
Autor:
Jordan M. Chinai, Qi Lin, Xiaoxin Ren, Lei Shi, Yao Wei, Mou Peng, Scott Moerdler, Phillip M. Galbo, Deyou Zheng, Liqiang Zhu, R. Alejandro Sica, Xingxing Zang, Bijan Etemad-Gilbertson, Hao Wang, Xudong Tang, Fangxia Guan
Publikováno v:
Sci Immunol
The B7 family ligand HERV-H LTR-associating protein 2 (HHLA2) is an attractive target for cancer immunotherapy due to its co-inhibitory function, over-expression in human cancers, and association with poor prognoses. However, the knowledge of the HHL