Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Xiaoxiang Gu"'
Autor:
Fangyan Gao, Yueyao Wu, Runtian Wang, Yuhui Yao, Yiqiu Liu, Lingling Fan, Jingtong Xu, Jian Zhang, Xin Han, Xiaoxiang Guan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 6, Pp 2685-2697 (2024)
Targeting androgen receptor (AR) has shown great therapeutic potential in triple-negative breast cancer (TNBC), yet its efficacy remains unsatisfactory. Here, we aimed to identify promising targeted agents that synergize with enzalutamide, a second-g
Externí odkaz:
https://doaj.org/article/45f66f1ea509476a91a29259b00bd1bf
Autor:
Feng Xu, Kun Xu, Lingling Fan, Xintong Li, Yiqiu Liu, Fang Yang, Chengjun Zhu, Xiaoxiang Guan, Ting Gao, Xiuyuan Hao
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 3, Pp 338-349 (2024)
Abstract. Background:. Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer associated with poor prognosis and limited treatment options. The androgen receptor (AR) has emerged as a potential therapeutic target for luminal andr
Externí odkaz:
https://doaj.org/article/7f67d94dc649460791ac6bafbcb9fa86
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Breast cancer, a highly fatal disease due to its tendency to metastasize, is the most prevalent form of malignant tumors among women worldwide. Numerous studies indicate that breast cancer exhibits a unique predilection for metastasis to spe
Externí odkaz:
https://doaj.org/article/456c3af6f3f44d8dbd7c2ec2b4fddcb9
Publikováno v:
Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 25(1)
To uncover the potential function of long non-coding RNA (lncRNA) ZEB2-AS1 in the progression of colorectal cancer (CRC), and its underlying mechanism.Relative level of ZEB2-AS1 in CRC tissues and matched normal ones was determined by quantitative re
Autor:
Feng Xu, Ke Wang, Chengjun Zhu, Lingling Fan, Ye Zhu, Jacqueline F. Wang, Xintong Li, Yiqiu Liu, Yuhan Zhao, Chuandong Zhu, Wenwen Zhang, Fang Yang, Jian Xu, Zhe Li, Xiaoxiang Guan
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109506- (2024)
Summary: It is imperative to explore biomarkers that are both precise and readily accessible in the comprehensive management of breast cancer. A multicenter cohort, including 512 breast cancer patients and 198 nonneoplastic individuals, was recruited
Externí odkaz:
https://doaj.org/article/27376b7c048c4b1094b268728330fc22
Autor:
Zekun Li, Yongchun Pan, Shiyu Du, Yayao Li, Chao Chen, Hongxiu Song, Yueyao Wu, Xiaowei Luan, Qin Xu, Xiaoxiang Guan, Yujun Song, Xin Han
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 897-899 (2024)
Externí odkaz:
https://doaj.org/article/3124d034ec2641e580d10d6c0f431dd0
Publikováno v:
Materials & Design, Vol 238, Iss , Pp 112664- (2024)
Multi-component thin films and coatings (MCTFCs) with stable structure and excellent capability are gradually being applied to more complex extreme environment. In the review paper, we summary the recent research progress of MCTFCs and build the comp
Externí odkaz:
https://doaj.org/article/99ef9db7a8b84f35bf17ca6f5b5c093c
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Intra-tumoral heterogeneity (ITH) is a distinguished hallmark of cancer, and cancer stem cells (CSCs) contribute to this malignant characteristic. Therefore, it is of great significance to investigate and even target the regulator
Externí odkaz:
https://doaj.org/article/62d92eb037ea488b89deee11c0bd102a
Autor:
Chao Chen, Wu Zhong, Shiyu Du, Yayao Li, Yunfei Zeng, Kunguo Liu, Jingjing Yang, Xiaoxiang Guan, Xin Han
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 6, Pp 2510-2543 (2023)
CRISPR, as an emerging gene editing technology, has been widely used in multiple fields due to its convenient operation, less cost, high efficiency and precision. This robust and effective device has revolutionized the development of biomedical resea
Externí odkaz:
https://doaj.org/article/5c0033f60b8a49b8bc2830be90a2c6e1
Autor:
Xiaoxiang Guan, Yiwei Zhang, Ilgiz Gareev, Ozal Beylerli, Xinyuan Li, Guitian Lu, Lin Lv, Xin Hai
Publikováno v:
Non-coding RNA Research, Vol 8, Iss 4, Pp 693- (2023)
Externí odkaz:
https://doaj.org/article/7820b65879b54c858d2513e8861458ba