Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Xiaoxia Ge"'
Autor:
Lei Xie, Xiaoxia Ge, Hepan Tan, Li Xie, Yinliang Zhang, Thomas Hart, Xiaowei Yang, Philip E Bourne
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 5, p e1003554 (2014)
Genome-Wide Association Studies (GWAS), whole genome sequencing, and high-throughput omics techniques have generated vast amounts of genotypic and molecular phenotypic data. However, these data have not yet been fully explored to improve the effectiv
Externí odkaz:
https://doaj.org/article/887eee59d8f64889bf9afcc62529e4c1
Autor:
Jingwei Zhang, Xuyang Luo, Yi Fan, Wei Zhou, Shijie Ma, Yuwei Kang, Wei Yang, Xiaoxia Geng, Heping Zhang, Fei Deng
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Early identification of high-risk individuals with cisplatin-induced nephrotoxicity (CIN) is crucial for avoiding CIN and improving prognosis. In this study, we developed and validated a CIN prediction model based on general clini
Externí odkaz:
https://doaj.org/article/91b3dabde84f479b833512f897563cc6
Publikováno v:
Processes
Volume 9
Issue 2
Processes, Vol 9, Iss 292, p 292 (2021)
Volume 9
Issue 2
Processes, Vol 9, Iss 292, p 292 (2021)
Hypertoxic materials make it critical to ensure the safety of the fluorochemical engineering processes. This mainly depends on the over maintenance or the manual operations due to the lack of precise models and mechanism knowledge. To quantify the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76660984839bb583c51734e6c790e2c
Rational Drug Design still faces a major hurdle for the prediction of drug efficacy in vivo solely based on its binding affinity for the target in vitro. The traditional perspective has clearly proven to be inadequate as it lacks the consideration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3636243558ae16256b8152a7a0d337
Autor:
Marilyn R. Gunner, Xiaoxia Ge
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 84:639-654
Bacteriorhodopsin, a light activated protein that creates a proton gradient in halobacteria, has long served as a simple model of proton pumps. Within bacteriorhodopsin, several key sites undergo protonation changes during the photocycle, moving prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f91075c8a6634ab8c72b7afe74fda6b0
https://doi.org/10.1002/prot.25013
https://doi.org/10.1002/prot.25013
Publikováno v:
The Review of scientific instruments. 89(1)
A virtual reconstruction method of directly capturing phase information between different nominal frequency signals, without frequency transformation, is proposed in this paper, building a virtual standard frequency signal whose frequency equals the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf6b9b8e7c043e6a6a2a33ffaac0b366
https://pubmed.ncbi.nlm.nih.gov/29390666
https://pubmed.ncbi.nlm.nih.gov/29390666
Publikováno v:
Analytical & Bioanalytical Chemistry. Mar2007, Vol. 387 Issue 6, p2083-2089. 7p. 1 Diagram, 3 Charts, 5 Graphs.
Publikováno v:
Current Drug Targets. 14:952-958
The modern target-based drug discovery process, characterized by the one-drug-one-gene paradigm, has been of limited success. In contrast, phenotype-based screening produces thousands of active compounds but gives no hint as to what their molecular t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171a114d017e08705f5ef76b76a74acd
https://doi.org/10.2174/1389450111314090003
https://doi.org/10.2174/1389450111314090003
Autor:
Benoît Roux, Xiaoxia Ge
Publikováno v:
The Journal of Physical Chemistry B. 114:9525-9539
The interactions of the 50S subunit of bacterial ribosome with antibiotic sparsomycin (SPS) and five analogs (AN) are investigated through the calculation of the standard (absolute) binding free energy and the characterization of conformational dynam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21a2bb45448e77a73c6dd78e147637d
https://doi.org/10.1021/jp100579y
https://doi.org/10.1021/jp100579y
Publikováno v:
Analytical and Bioanalytical Chemistry. 387:2083-2089
A new spectrofluorimetric method was developed for the determination of trace amounts of coenzyme A (CoA). In the presence of periodic acid (H5IO6), CoA can remarkably enhance the fluorescence intensity of the Tb3+-ciprofloxacin (CIP) complex at 545
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c429614a293a1acfe26f431779830d
https://doi.org/10.1007/s00216-006-1075-0
https://doi.org/10.1007/s00216-006-1075-0