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Autor:
Zhichao Yu, Yanhong Yong, Xiaoxi Liu, Xingbin Ma, A. M. Abd El-Aty, Leling Li, Ziyuan Zhong, Xingyi Ye, Xianghong Ju
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Heat stress (HS) can affect the physiology and metabolism of animals. HS-induced intestinal inflammation in pigs is a common disease, causing severe diarrhea, that can result in substantial economic losses to the pig industry, but
Externí odkaz:
https://doaj.org/article/d457c5c181fa4fb39c65b275276970d6
Autor:
Kun Fang, Huizhe Xu, Shuai Yuan, Xiaoxi Li, Xiaoyu Chen, Xiushi Fan, Xiaoxin Gao, Lu Zhang, Shulan Sun, Xudong Zhu
Publikováno v:
Nutrition & Metabolism, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Metabolism reprogramming (MR) is one of the top ten hallmarks of malignant tumors. The aberrant activation of MR has been recognized as a critical contributory factor to the malignant progression of solid tumors. Moreover, various long non-c
Externí odkaz:
https://doaj.org/article/cbd9ac043ef2425896d4bcfb865eeeb3
Publikováno v:
BioMedical Engineering OnLine, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Vascular transplantation is an effective treatment for severe vascular lesions. The design of the bioactive and mechanical properties of small-caliber vascular grafts is critical for their application in tissue engineering. In thi
Externí odkaz:
https://doaj.org/article/c3153541de514d269a3aae0a3ca992b6
Autor:
Pengli Li, Ziwei Zhai, Yixin Fan, Wei Li, Minjing Ke, Xiaoxi Li, Huiru Gao, Yu Fu, Zhaoyi Ma, Wenhui Zhang, Hongyan Yi, Jin Ming, Yue Qin, Bo Wang, Junqi Kuang, Duanqing Pei
Publikováno v:
Oncogenesis, Vol 13, Iss 1, Pp 1-9 (2024)
Abstract SS18-SSX onco-fusion protein formed through aberrant chromosomal translocation t (X, 18; p11, q11), is the hallmark and plays a critical role in synovial sarcomagenesis. The recent works indicated that both the pathological SS18-SSX tumorige
Externí odkaz:
https://doaj.org/article/2926b1dcc2ee44cd848f572a30742cff
Autor:
Xiali Lv, Yu Tian, Fengxia Wu, Xiaoxi Luan, Fenghua Li, Zhili Shen, Guobao Xu, Kun Liu, Wenxin Niu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Helicoid plasmonic nanoparticles with intrinsic chirality are an emerging class of artificial chiral materials with tailorable properties. The ability to extend their chiroplasmonic responses to the near-infrared (NIR) range is critically im
Externí odkaz:
https://doaj.org/article/5ffdcf92d56c49228fa7016d9b0700e0
Autor:
Jiaojiao Yu, Yujin Xiang, Yuzhen Gao, Shan Chang, Ren Kong, Xiaoxi Lv, Jinmei Yu, Yunjie Jin, Chenxi Li, Yiran Ma, Zhenhe Wang, Jichao Zhou, Hongyu Yuan, Shuang Shang, Fang Hua, Xiaowei Zhang, Bing Cui, Pingping Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 10, Pp 4378-4395 (2024)
Protein kinase C α (PKCα) regulates diverse biological functions of cancer cells and is a promising therapeutic target. However, clinical trials of PKC-targeted therapies have not yielded satisfactory results. Recent studies have also indicated a t
Externí odkaz:
https://doaj.org/article/a4b96f8a86b540568012cf7c8c5536c4
Autor:
Masatoshi Matsunami, Minako Imamura, Asuka Ashikari, Xiaoxi Liu, Kohei Tomizuka, Keiko Hikino, Kosei Miwa, Katsumi Kadekawa, Tetsuji Suda, The Biobank Japan project, Koichi Matsuda, Minoru Miyazato, Chikashi Terao, Shiro Maeda
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract Pelvic organ prolapse (POP) affects approximately 40% of elderly women, characterized by the descent of the pelvic organs into the vaginal cavity. Here we present the results of a genome-wide association study (GWAS) for susceptibility to PO
Externí odkaz:
https://doaj.org/article/ee39f2503acb4b45b036860578410f82
Autor:
Mengting Yang, Puwen Zhang, Jillian Halladay, Kun Zou, Imti Choonara, Xiaorui Ji, Shuya Zhang, Weiyi Yan, Liang Huang, Xiaoxi Lu, Huiqing Wang, Yuxin Jiang, Xinyu Liu, Linan Zeng, Lingli Zhang, Gordon H. Guyatt
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-36 (2024)
Abstract Background Medication Treatment Satisfaction (M-TS) from the patients’ perspective is important for comprehensively evaluating the effect of medicines. The extent to which current patient-reported outcome measures (PROMs) for M-TS are vali
Externí odkaz:
https://doaj.org/article/b999475f8f03454c8a48a4104ffd9ebf
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Molecular targeted therapy resistance remains a major challenge in treating lung adenocarcinoma (LUAD). The resistance of Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs, epidermal growth factor receptor-tyrosine kinas
Externí odkaz:
https://doaj.org/article/82880fd7d7644e3c8d2b9ace73f79c30