Zobrazeno 1 - 10
of 484
pro vyhledávání: '"Xiaoting CHEN"'
Autor:
Qiang Wang, Taehyeung Kim, Marta Martínez-Bonet, Vitor R. C. Aguiar, Sangwan Sim, Jing Cui, Jeffrey A. Sparks, Xiaoting Chen, Marc Todd, Brian Wauford, Miranda C. Marion, Carl D. Langefeld, Matthew T. Weirauch, Maria Gutierrez-Arcelus, Peter A. Nigrovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Genome-wide association studies implicate multiple loci in risk for systemic lupus erythematosus (SLE), but few contain exonic variants, rendering systematic identification of non-coding variants essential to decoding SLE genetics. We utiliz
Externí odkaz:
https://doaj.org/article/1e3df32c4843408cb3495d4e0d4bcf9e
Publikováno v:
International Journal of Smart and Nano Materials, Vol 15, Iss 3, Pp 652-696 (2024)
The ultra-precision field is popular for its micro-nanometer positioning accuracy and large working stroke. Piezoelectric actuators based on the stick-slip operational principle exhibit superior performance characteristics, making them stand out with
Externí odkaz:
https://doaj.org/article/a425b0e5674741328faa427dc390fc85
Autor:
Hui Yang, Xiaoting Chen, Zeng Wang, Zongliang Zhang, Meijun Zheng, Aiping Tong, Yijun Dong, Siyuan Luan, Yongdong Chen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 10 (2024)
Background Antibody-drug conjugates (ADCs) offer a promising approach, combining monoclonal antibodies with chemotherapeutic drugs to target cancer cells effectively while minimizing toxicity.Methods This study examined the therapeutic efficacy and p
Externí odkaz:
https://doaj.org/article/84068cf8e9dc476b901023c1dde60bb3
Autor:
Xiaoting Chen, Wen Zhao, Hejiang Yu, Shuang Wang, Chengjun Wang, Yanan Song, Xue Meng, Jisheng Li
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Lung squamous cell carcinoma (LUSC) is the second most common pathological type of non-small cell lung cancer (NSCLC). However, compared with lung adenocarcinoma (LUAD), the incidence of driver gene mutations in LUSC is relatively lower and treatment
Externí odkaz:
https://doaj.org/article/bb995ce2bd67453d83a6f0d58e1901ff
Autor:
Ying Li, Shujuan Du, Kun Zhou, Yulin Zhang, Xiaoting Chen, Caixia Zhu, Yuping Jia, Yuyan Wang, Daizhou Zhang, Fang Wei, Yin Tong, Qiliang Cai
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110581- (2024)
Summary: Epstein-Barr virus (EBV), an oncogenic herpesvirus, is predominantly found in the latent infection form and is highly associated with many human malignancies, which mainly have poor prognoses and no effective treatments. Here, we obtained th
Externí odkaz:
https://doaj.org/article/ca2529dbd850458a92c0387400ddfbfb
Publikováno v:
Gaoyuan qixiang, Vol 43, Iss 2, Pp 342-352 (2024)
Based on the daily summer precipitation data of 99 national stations in Shaanxi Province and the ERA5 reanalysis data from 1979 to 2021， the temporal and spatial variations of extreme summer precipitation and the corresponding large-scale circulati
Externí odkaz:
https://doaj.org/article/b88b63fbd6d348309413b84365ff71ef
Autor:
Kenyatta C. M. F. Viel, Sreeja Parameswaran, Omer A. Donmez, Carmy R. Forney, Matthew R. Hass, Cailing Yin, Sydney H. Jones, Hayley K. Prosser, Arame A. Diouf, Olivia E. Gittens, Lee E. Edsall, Xiaoting Chen, Hope Rowden, Katelyn A. Dunn, Rui Guo, Andrew VonHandorf, Merrin Man Long Leong, Kevin Ernst, Kenneth M. Kaufman, Lucinda P. Lawson, Ben Gewurz, Bo Zhao, Leah C. Kottyan, Matthew T. Weirauch
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Background There are two major genetic types of Epstein-Barr Virus (EBV): type 1 (EBV-1) and type 2 (EBV-2). EBV functions by manipulating gene expression in host B cells, using virus-encoded gene regulatory proteins including Epstein-Barr N
Externí odkaz:
https://doaj.org/article/155fc47c06e74fd5b11dee66241b344d
Autor:
Taehyeung Kim, Marta Martínez-Bonet, Qiang Wang, Nicolaj Hackert, Jeffrey A. Sparks, Yuriy Baglaenko, Byunghee Koh, Roxane Darbousset, Raquel Laza-Briviesca, Xiaoting Chen, Vitor R. C. Aguiar, Darren J. Chiu, Harm-Jan Westra, Maria Gutierrez-Arcelus, Matthew T. Weirauch, Soumya Raychaudhuri, Deepak A. Rao, Peter A. Nigrovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Fine-mapping and functional studies implicate rs117701653, a non-coding single nucleotide polymorphism in the CD28/CTLA4/ICOS locus, as a risk variant for rheumatoid arthritis and type 1 diabetes. Here, using DNA pulldown, mass spectrometry,
Externí odkaz:
https://doaj.org/article/89591f74d78449f789de95d34d7df2b8
Publikováno v:
MedComm, Vol 5, Iss 7, Pp n/a-n/a (2024)
Abstract Hyperuricemia is an essential risk factor in chronic kidney disease (CKD), while urate‐lowering therapy to prevent or delay CKD is controversial. Alternatively activated macrophages in response to local microenvironment play diverse roles
Externí odkaz:
https://doaj.org/article/041d734355794d32a09c0d48fe9c08b0
Autor:
Shuli Ma, Jie Ge, Lei Qin, Xiaoting Chen, Linlin Du, Yanbo Qi, Li Bai, Yunfeng Han, Zhiping Xie, Jiaxin Chen, Yuehui Jia
Publikováno v:
JMIR Public Health and Surveillance, Vol 10, p e57807 (2024)
BackgroundThe World Health Organization declared mpox an international public health emergency. Since January 1, 2022, China has been ranked among the top 10 countries most affected by the mpox outbreak globally. However, there is a lack of spatial e
Externí odkaz:
https://doaj.org/article/eb214fcef50a4e9eb2b8dcf9cdd7c193