Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Xiaotao Dong"'
Autor:
Yanjiang Liu, Gongcheng Hu, Shengxiong Yang, Mingze Yao, Zicong Liu, Chenghong Yan, Yulin Wen, Wangfang Ping, Juehan Wang, Yawei Song, Xiaotao Dong, Guangjin Pan, Hongjie Yao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Polycomb repressive complex 1 (PRC1) comprises two different complexes: CBX-containing canonical PRC1 (cPRC1) and RYBP/YAF2-containing variant PRC1 (vPRC1). RYBP-vPRC1 or YAF2-vPRC1 catalyzes H2AK119ub through a positive-feedback model; howe
Externí odkaz:
https://doaj.org/article/a7d987a00c454b1f816eae478dc06abc
Autor:
Kunlun Wang, Xiaotao Dong
Publikováno v:
Asian Journal of Surgery, Vol 46, Iss 12, Pp 5962-5963 (2023)
Externí odkaz:
https://doaj.org/article/81620893cf1546c2bf22076bec645128
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ObjectivePatients with pancreatic cancer (PC) have a poor prognosis. Radiotherapy (RT) is a standard palliative treatment in clinical practice, and there is no effective clinical prediction model to predict the prognosis of PC patients receiving radi
Externí odkaz:
https://doaj.org/article/93db1ec78a4b4f6889ad3e42d8f4abd3
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeTo compare Whole-brain radiation therapy with simultaneous integrated boost (WBRT+SIB) to stereotactic radiosurgery (SRS)for non-small cell lung cancer (NSCLC)with brain metastases (BMs)in terms of overall survival (OS), intracranial progressi
Externí odkaz:
https://doaj.org/article/daf8c5bcebc84806b1f3a223bd19577a
Publikováno v:
Pathology and Oncology Research, Vol 28 (2022)
Background: Immunotherapy is recommended by the NCCN (National Comprehensive Cancer Network) guidelines as the standard second-line treatment for advanced esophageal squamous cell carcinoma (ESCC). Patients with advanced ESCC can benefit from immunot
Externí odkaz:
https://doaj.org/article/494488418ff0462ea9d9d24b32626e4f
Autor:
Yawei Song, Zhengyu Liang, Jie Zhang, Gongcheng Hu, Juehan Wang, Yaoyi Li, Rong Guo, Xiaotao Dong, Isaac A. Babarinde, Wangfang Ping, Ying-Liang Sheng, Huanhuan Li, Zhaoming Chen, Minghui Gao, Yang Chen, Ge Shan, Michael Q. Zhang, Andrew P. Hutchins, Xiang-Dong Fu, Hongjie Yao
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110626- (2022)
Summary: CTCF mediates chromatin insulation and long-distance enhancer-promoter (EP) interactions; however, little is known about how these regulatory functions are partitioned among target genes in key biological processes. Here, we show that Ctcf e
Externí odkaz:
https://doaj.org/article/3a69b9c96a264b60bda6a0b33f046877
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 15, Iss 3, Pp 356-364 (2020)
This study demonstrates that our previously reported polywraplex, a synthetic siRNA carrier consisting of a uni-molecular polyplex core of customizable size and a self-assembled tri-block copolymer envelop, may be constructed using dendrimers as the
Externí odkaz:
https://doaj.org/article/5e62f2843ad1496b9335f88a107c95b5
Autor:
Jiao Li, Kaimeng Huang, Gongcheng Hu, Isaac A. Babarinde, Yaoyi Li, Xiaotao Dong, Yu-Sheng Chen, Liping Shang, Wenjing Guo, Junwei Wang, Zhaoming Chen, Andrew P. Hutchins, Yun-Gui Yang, Hongjie Yao
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
CTCF plays key roles in gene regulation, chromatin insulation and organizing the higher-order chromatin architecture of mammalian genomes. Here the authors investigate the function an alternatively spliced shorter CTCF isoform, finding that this isof
Externí odkaz:
https://doaj.org/article/20b7e015e06445819e1fb1c7fa1b68e6
Autor:
Xiaotao Dong, Rong Guo, Tianrong Ji, Jie Zhang, Jun Xu, Yaoyi Li, Yingliang Sheng, Yuxiang Wang, Ke Fang, Yulin Wen, Bei Liu, Gongcheng Hu, Hongkui Deng, Hongjie Yao
Publikováno v:
Nucleic Acids Research. 50:12019-12038
Although extended pluripotent stem cells (EPSCs) have the potential to form both embryonic and extraembryonic lineages, how their transcriptional regulatory mechanism differs from that of embryonic stem cells (ESCs) remains unclear. Here, we discover
Publikováno v:
Nucleic Acids Research
CTCF plays a pivotal role in mediating chromatin interactions, but it does not do so alone. A number of factors have been reported to co-localize with CTCF and regulate CTCF loops, but no comprehensive analysis of binding partners has been performed.