Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Xiaosong Luan"'
Autor:
Markus Bluemel, Kurt Forrer, Markus Smolny, Nebojsa Milovic, Olivier Graf, Hui Zhao, Xiaosong Luan
Publikováno v:
Journal of Pharmaceutical Sciences. 99:2279-2294
Since each antibody has its unique physical chemical properties, optimal formulation for one antibody is likely not applicable for the others. To rapidly screen multiple antibody formulations, an automated system was constructed to perform sample pre
Publikováno v:
International Journal of Pharmaceutics. 324:168-175
The objective of this study was to identify key variables affecting the initial release (burst) and the encapsulation of leuprolide acetate-containing poly(lactide- co -glycolide) (PLGA) microparticles, which were prepared by the cosolvent evaporatio
Autor:
Roland Bodmeier, Xiaosong Luan
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 63:205-214
Leuprolide acetate-loaded poly(lactide-co-glycolide) (PLGA RG503H) microparticles prepared by the solvent evaporation method had a tri-phasic drug release pattern over a duration of up to 2 months. An initial release was followed by a slow drug relea
Publikováno v:
Synthesis. 2005:3571-3580
6-lodoisocoumarin 4 and its aza-analogue, 6-iodo-1-oxo-isoquinoline 29, were efficiently prepared from vanillin in seven and six steps, respectively. Key transformations in their syntheses were achieved by directed ortho-lithiation and variations of
Autor:
Roland Bodmeier, Xiaosong Luan
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 110(2)
The objective was to investigate the influence of poly(lactide-co-glycolide) (PLGA) type (molecular weight and end-group functionality) on the leuprolide release from in situ forming microparticle (ISM) systems. ISM systems are based on an emulsion o
Autor:
Xiaosong Luan, Roland Bodmeier
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 27(2-3)
The objective of present study was to control the delivery of leuprolide acetate using in situ forming microparticle (ISM) systems. A solution of leuprolide acetate and poly(lactide-co-glycolide) (PLGA RG 503H) or poly(lactide) (PLA R 202H) in N-meth
Autor:
Hui Zhao1, Graf, Olivier1, Milovic, Nebojsa1, Xiaosong Luan2, Bluemel, Markus1, Smolny, Markus1, Forrer, Kurt1 kurt.forrer@novartis.com
Publikováno v:
Journal of Pharmaceutical Sciences. May2010, Vol. 99 Issue 5, p2279-2294. 16p. 2 Color Photographs, 3 Diagrams, 6 Charts, 7 Graphs.