Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Xiaoru Duan"'
Autor:
Suwen Liu, Mengwen He, Jian Jiang, Xiaoru Duan, Bao Chai, Jingyu Zhang, Qingxiao Tao, Hongxiang Chen
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Psoriasis is an immune-mediated inflammatory skin disease, involving a complex interplay between genetic and environmental factors. Previous studies have demonstrated that genetic factors play a major role in the pathogenesis of psoriasis. H
Externí odkaz:
https://doaj.org/article/ac76ca464371420dabbc436d7fc1cbb2
Autor:
Lijuan Jiang, Wenlin Qiu, Xuefei Wang, Xiaoru Duan, Xiaoxiao Han, Tong Yu, Shenghui Wen, Zhijun Luo, Ruizhi Feng, Yao Teng, Haifeng Yin, Christian M. Hedrich, Guo-Min Deng
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107749- (2023)
Summary: Glucocorticoid-induced osteoporosis (GIOP) is a severe and common complication of long-term usage of glucocorticoids (GCs) and lacks of efficient therapy. Here, we investigated the mechanism of anti-inflammation effect and osteoclastogenesis
Externí odkaz:
https://doaj.org/article/dbf48dc277ea4dd7ac879cb4c070f03b
Autor:
Yi Kong, Jian Jiang, Yuqiong Huang, Li Li, Xin Liu, Zilin Jin, Fen Wei, Xinxin Liu, Song Zhang, Xiaoru Duan, Yonghui Zhang, Qingyi Tong, Hongxiang Chen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 155, Iss , Pp 113741- (2022)
Melanoma is the most lethal skin cancer with rising incidence worldwide. Despite significant advances in target therapy and immunotherapy, low response rates and the development of drug resistance remain key clinical barriers affecting patient progno
Externí odkaz:
https://doaj.org/article/df9e89dfeb78410abf4d118a2f0e8a26
Autor:
Yuyue Zuo, Lei Dai, Li Li, Yuqiong Huang, Xinxin Liu, Xin Liu, Xiaoru Duan, Su Jiang, Guo-Min Deng, Hongxiang Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Psoriasis is characterized by keratinocyte proliferation and massive inflammatory leukocytes infiltration, affecting 0.14%–1.99% of the world’s population. Our aim was to identify novel potential therapeutic strategies for psoriasis.M
Externí odkaz:
https://doaj.org/article/385c5cc1db8a4572bbee410ca1813941
Autor:
Lijuan Jiang, Xiaoxiao Han, Wenlin Qiu, Tong Yu, Ruizhi Feng, Xuefei Wang, Xiaoru Duan, Guo-Min Deng
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disorder characterized by high autoantibodies levels and multiorgan tissue damage. The current study investigated the role of CD64 in SLE patients and animal models. According to a flow
Externí odkaz:
https://doaj.org/article/872c9fad23aa45dd855051dda4908ae6
Autor:
Li Li, Xin Liu, Wenqiang Ge, Chao Chen, Yuqiong Huang, Zilin Jin, Muouyang Zhan, Xiaoru Duan, Xinxin Liu, Yi Kong, Jian Jiang, Xuemei Li, Xin Zeng, Fei Li, Shibin Xu, Man Li, Hongxiang Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Cannabinoid receptor 2 (CB2R) is a potential target for anti-inflammatory and pain therapeutics given its significant immunomodulatory and analgesic effects. However, the role of CB2R in imiquimod (IMQ)-induced psoriasiform dermatitis (Ps
Externí odkaz:
https://doaj.org/article/0b038b9305f24fb7bc2f0e82f50da56e
Autor:
Song Zhang, Yingmiao Zhang, Lu Gan, Fen Wei, Bao Chai, Amaneh Abdel Hafez A Aljaafreh, Xinxin Liu, Xiaoru Duan, Jian Jiang, Xin Wang, Mengwen He, Xian Huang, Huahua Cai, Tie Chen, Hongxiang Chen
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Asymptomatic/subclinical gonococcal infections in females continue to be prevalent within the general population, thus emerging as a global health problem. However, the reasons for these clinical manifestations are unknown. Our group had previously f
Externí odkaz:
https://doaj.org/article/d2f4662200984388b6e1cdd4a77fda81
Autor:
Nian Liu, Zijian Liu, Xinxin Liu, Xiaoru Duan, Yuqiong Huang, Zilin Jin, Yi Niu, Liling Zhang, Hongxiang Chen
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Melanoma is the leading cause of cancer-related death among skin tumors, with an increasing incidence worldwide. Few studies have effectively investigated the significance of an immune-related gene (IRG) signature for melanoma prognosis. Here, we con
Externí odkaz:
https://doaj.org/article/c096c9ee603347fc8195a66fc2bd4468
Autor:
Xin Wang, Xinxin Liu, Xiaoru Duan, Ke Zhu, Song Zhang, Lu Gan, Nian Liu, Himanshu Jaypaul, Johanna T. Makamure, Zhangyin Ming, Hongxiang Chen
Publikováno v:
Acta Dermato-Venereologica, Vol 98, Iss 6, Pp 585-593 (2018)
Epigenetics plays an important role in the development and progression of many diseases. There is increasing evidence for the importance of epigenetic modifications in the progression of psoriasis. The aim of this study was to examine the role and po
Externí odkaz:
https://doaj.org/article/8d78f5a1b7fc47909dd4521ce885a87b
Autor:
Xinxin Liu, Xin Wang, Xiaoru Duan, Devesh Poorun, Juntao Xu, Song Zhang, Lu Gan, Mengwen He, Ke Zhu, Zhangyin Ming, Feng Hu, Hongxiang Chen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Psoriasis is a chronic inflammatory skin disease that affects 2–3% of the global population, and there is still no known possibility of a cure. Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-
Externí odkaz:
https://doaj.org/article/6def1d129db54deaa68cb02207cc75b0