Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Xiaorong Liang"'
Autor:
Guonan Feng, Di Fu, Xi Chen, Jintao Liu, Xinyan Yang, Xiaorong Liang, Penghao Lv, Di Zhao, Minggao Zuo, Guanghua Yu
Publikováno v:
AIP Advances, Vol 13, Iss 5, Pp 055022-055022-8 (2023)
We investigated the spin–orbit torque (SOT) and unidirectional spin Hall magnetoresistance (USMR) in Pt/CoFe/Ta trilayer as well as Pt/CoFe and CoFe/Ta bilayers with in-plane magnetic anisotropy by performing transverse and longitudinal second harm
Externí odkaz:
https://doaj.org/article/c8f33b2f704846e291a48c205255957b
Autor:
Asha Nayak-Kapoor, Zhonglin Hao, Ramses Sadek, Robin Dobbins, Lisa Marshall, Nicholas N. Vahanian, W. Jay Ramsey, Eugene Kennedy, Mario R. Mautino, Charles J. Link, Ray S. Lin, Stephanie Royer-Joo, Xiaorong Liang, Laurent Salphati, Kari M. Morrissey, Sami Mahrus, Bruce McCall, Andrea Pirzkall, David H. Munn, John E. Janik, Samir N. Khleif
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-12 (2018)
Abstract Background Indoleamine-2,3-dioxygenase 1 (IDO1) catalyzes the oxidation of tryptophan into kynurenine and is partially responsible for acquired immune tolerance associated with cancer. The IDO1 small molecule inhibitor navoximod (GDC-0919, N
Externí odkaz:
https://doaj.org/article/fa3f41ad888d41f5a1c759f8b6fa21b2
Autor:
Thomas O'Brien, Jason Oeh, Yang Xiao, Xiaorong Liang, Alexander Vanderbilt, Ann Qin, Lulu Yang, Leslie B. Lee, Justin Ly, Ely Cosino, Jennifer A. LaCap, Annie Ogasawara, Simon Williams, Michelle Nannini, Bianca M. Liederer, Peter Jackson, Peter S. Dragovich, Deepak Sampath
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 12, Pp 1314-1329 (2013)
Nicotinamide adenine dinucleotide (NAD) is a metabolite essential for cell survival and generated de novo from tryptophan or recycled from nicotinamide (NAM) through the nicotinamide phosphoribosyltransferase (NAMPT)-dependent salvage pathway. Altern
Externí odkaz:
https://doaj.org/article/8535a58d3d9848dc8bfb8adf33b8bae4
Autor:
Yang Xiao, Kristi Elkins, Jenni K Durieux, Leslie Lee, Jason Oeh, Lulu X Yang, Xiaorong Liang, Chris DelNagro, Jarrod Tremayne, Mandy Kwong, Bianca M Liederer, Peter K Jackson, Lisa D Belmont, Deepak Sampath, Thomas O'Brien
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 10, Pp 1151-1160 (2013)
Nicotinamide adenine dinucleotide (NAD) is a critical metabolite that is required for a range of cellular reactions. A key enzyme in the NAD salvage pathway is nicotinamide phosphoribosyl transferase (NAMPT), and here, we describe GNE-618, an NAMPT i
Externí odkaz:
https://doaj.org/article/465978c254fd40a9b156667dad2f834b
Autor:
Yuliang Zhao, Tao Li, Guangyuan Zhang, Xiaorong Liang, Yanxia Wang, Jiansheng Kang, Jiangang Ma
Publikováno v:
European Archives of Oto-Rhino-Laryngology. 280:2435-2443
Objective Bariatric surgery (BS) is considered one of the most effective treatments for obese individuals with Obstructive Sleep Apnea (OSA). However, otolaryngologists have raised concerns about the structural alterations caused by BS on the upper r
Autor:
Ryan Johnson, Imran Rehmani, Mark Leahy, Abigail Walker, Xiaorong Liang, Brian Dean, Jianshuang Wang
Publikováno v:
Bioanalysis. 14:1377-1389
Volumetric absorption microsampling devices offer minimally invasive and user-friendly collection of capillary blood in volumes as low as 10 μl. Herein we describe the assay validation for determination of the selective estrogen receptor degrader gi
Autor:
Lisa D. Belmont, Hartmut Koeppen, Richard Bourgon, Thomas O'Brien, Robert L. Yauch, Xiaorong Liang, Bianca Liederer, Peter M. Haverty, Thinh Pham, Yang Xiao, Dane Mohl, Pan Du, Thomas Holcomb, Kimberly Walter, Kristi Elkins, David S. Shames
Purpose: We sought to identify predictive biomarkers for a novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitor.Experimental Design: We use a NAMPT inhibitor, GNE-617, to evaluate nicotinic acid rescue status in a panel of more than 400 can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e84aa7961f32a2031d250e784a4c317
https://doi.org/10.1158/1078-0432.c.6520628.v1
https://doi.org/10.1158/1078-0432.c.6520628.v1
Autor:
Lisa D. Belmont, Hartmut Koeppen, Richard Bourgon, Thomas O'Brien, Robert L. Yauch, Xiaorong Liang, Bianca Liederer, Peter M. Haverty, Thinh Pham, Yang Xiao, Dane Mohl, Pan Du, Thomas Holcomb, Kimberly Walter, Kristi Elkins, David S. Shames
PDF file 122K, A) Chemical structure of GNE-617, B) cellular NAD and ATP levels in H522 cells after exposure to 4nM GNE-617, C) correlation of NAPRT1 mRNA and protein (n=32, spearman r= 0.88, p,0.0001)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3078920a930d4fcc697360aeedd937c0
https://doi.org/10.1158/1078-0432.22446035
https://doi.org/10.1158/1078-0432.22446035
Autor:
Lisa D. Belmont, Hartmut Koeppen, Richard Bourgon, Thomas O'Brien, Robert L. Yauch, Xiaorong Liang, Bianca Liederer, Peter M. Haverty, Thinh Pham, Yang Xiao, Dane Mohl, Pan Du, Thomas Holcomb, Kimberly Walter, Kristi Elkins, David S. Shames
PDF file 141K, Supplementary methods for NAD quantification and the QMSP assay. Table S1 GNE-617 IC50 and mRNA Levels of NAMPT and NAPRT1, Table S2 Cell Lines Not Rescued with 10uM NA, Table S3 Cell Lines with Low NAPRT1 Expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ead523cff3b9f9c55d3f8c544a360c9
https://doi.org/10.1158/1078-0432.22446032.v1
https://doi.org/10.1158/1078-0432.22446032.v1
Publikováno v:
Biomedical Chromatography. 37
Microsampling technology for dried blood-derived samples provides an advantageous alternative to conventional venous blood for drug quantitation. Unlike conventional whole blood microsampling techniques, Noviplex is a novel, card-based technology for