Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Xiaorong Dong"'
Autor:
Yunshang Chen, Xue Feng, Zilong Wu, Yongqiang Yang, Xinrui Rao, Rui Meng, Sheng Zhang, Xiaorong Dong, Shuangbing Xu, Gang Wu, Xiaohua Jie
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-18 (2024)
Abstract Background Radioresistance is a key clinical constraint on the efficacy of radiotherapy in lung cancer patients. REV1 DNA directed polymerase (REV1) plays an important role in repairing DNA damage and maintaining genomic stability. However,
Externí odkaz:
https://doaj.org/article/9a17e0830ff24a45930d6874330c15a4
Autor:
Lichao Liu, Jian Wang, Ying Wang, Lingjuan Chen, Ling Peng, Yawen Bin, Peng Ding, Ruiguang Zhang, Fan Tong, Xiaorong Dong
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Background Brain metastasis is one of the main causes of recurrence and death in non-small cell lung cancer (NSCLC). Although radiotherapy is the main local therapy for brain metastasis, it is inevitable that some cancer cells become resista
Externí odkaz:
https://doaj.org/article/836e2093d6fa48c1b229690be5a03dc9
Autor:
Zixuan Li, Huichan Xue, Jinsong Li, Zhikun Zheng, Zhiwei Liu, Xiaorong Dong, Hongbo Wang, Jing Chen, Shuangbing Xu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Background The evasion of the immune response by tumor cells through programmed death-ligand 1 (PD-L1) has been identified as a factor contributing to resistance to radioimmunotherapy in lung cancer patients. However, the precise molecular m
Externí odkaz:
https://doaj.org/article/1a8bcd84e3f546e3aec8b5b1a9609f07
Autor:
Ying Cheng, Chunjiao Wu, Lin Wu, Jun Zhao, Yanqiu Zhao, Lulu Chen, Ying Xin, Liang Zhang, Pinhua Pan, Xingya Li, Juan Li, Xiaorong Dong, Ke Tang, Emei Gao, Fei Yu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract This single-arm, multi-center clinical trial aimed to evaluate the safety, tolerability, DLT, recommended dose (RD), preliminary efficacy, and pharmacokinetics (PK) characteristics of lurbinectedin, a selective inhibitor of oncogenic transcr
Externí odkaz:
https://doaj.org/article/aaeda2d4fe5546aaa40b29b0239798e3
Autor:
Di Zheng, Yanhong Shang, Jian Ni, Ling Peng, Xiaoming Tan, Zhaoxia Dai, Yizhuo Zhao, Aiqin Gu, Jiying Wang, Yanyan Song, Xiaofeng Li, Junping Zhang, Wei Heng, Cuiying Zhang, Chunling Liu, Hui Li, Yingying Du, Jianfang Xu, Dan Wu, Xuwei Cai, Rui Meng, Xiaorong Dong, Yaoping Ruan, Liyan Jiang
Publikováno v:
JMIR Cancer, Vol 10, p e45331 (2024)
BackgroundTelehealth has emerged as a popular channel for providing outpatient services in many countries. However, the majority of telehealth systems focus on operational functions and offer only a sectional patient journey at most. Experiences with
Externí odkaz:
https://doaj.org/article/d037871f5aac45d6bc4e9eaae407ce25
Autor:
Yunshang Chen, Yun Zhou, Xue Feng, Zilong Wu, Yongqiang Yang, Xinrui Rao, Rui Zhou, Rui Meng, Xiaorong Dong, Shuangbing Xu, Sheng Zhang, Gang Wu, Xiaohua Jie
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Radioresistance is a major constraint on the efficacy of lung cancer radiotherapy, but its mechanism has not been fully elucidated. Here, we found that FBXO22 was aberrantly highly expressed in lung cancer and that FBXO22 knockdown increased
Externí odkaz:
https://doaj.org/article/24cc7d0f86ba4eb685bae0bb02f901b9
Autor:
Jianchun Duan, Wenfeng Fang, Hairong Xu, Jinliang Wang, Yuan Chen, Yi Ding, Xiaorong Dong, Yun Fan, Beili Gao, Jie Hu, Yan Huang, Cheng Huang, Dingzhi Huang, Wenhua Liang, Lizhu Lin, Hui Liu, Zhiyong Ma, Meiqi Shi, Yong Song, Chuanhao Tang, Jialei Wang, Lifeng Wang, Yongfeng Wang, Zhehai Wang, Nong Yang, Yu Yao, Yan Yu, Qitao Yu, Hongmei Zhang, Jun Zhao, Mingfang Zhao, Zhengfei Zhu, Xiaohui Niu, Li Zhang, Jie Wang
Publikováno v:
Journal of the National Cancer Center, Vol 3, Iss 4, Pp 256-265 (2023)
Lung cancer is the leading cause of cancer-related deaths worldwide. Bone is a common metastatic site of lung cancer, about 50% of bone metastatic patients will experience skeletal related events (SREs). SREs not only seriously impact the quality of
Externí odkaz:
https://doaj.org/article/64c371bf622d46b68856e83b202c08a9
Autor:
Rui Zhou, Fan Tong, Yongchang Zhang, Ruigang Zhang, Yawen Bin, Sheng Zhang, Nong Yang, Xiaorong Dong
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionThis study aimed to elucidate the relationship between dynamic genomic mutation alteration and pseudoprogression (PsPD)/hyperprogressive disease (HPD) in immunotherapy-treated advanced non-small-cell lung cancer (NSCLC), to provide clinic
Externí odkaz:
https://doaj.org/article/2f540bf6308a4837b3d9efab7ff47ca4
Autor:
Shen Zhao, Wu Zhuang, Baohui Han, Zhengbo Song, Wei Guo, Feng Luo, Lin Wu, Yi Hu, Huijuan Wang, Xiaorong Dong, Da Jiang, Mingxia Wang, Liyun Miao, Qian Wang, Junping Zhang, Zhenming Fu, Yihua Huang, Chunwei Xu, Longyu Hu, Lei Li, Rong Hu, Yang Yang, Mengke Li, Xiugao Yang, Li Zhang, Yan Huang, Wenfeng Fang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract EGFR exon 20 insertion (20ins)-positive non-small-cell lung cancer (NSCLC) is an uncommon disease with limited therapeutic options and dismal prognosis. Here we report the activity, tolerability, potential mechanisms of response and resistan
Externí odkaz:
https://doaj.org/article/845e14a04dc6483197124325ef24177b
Autor:
Ling Peng, Yawen Bin, Peng Ding, Lingjuan Chen, Hao Zeng, Zelong Xu, Liyan Ji, Xuan Gao, Pian Liu, Ye Wang, Sheng Zhang, Zhongxing Liao, Xuefeng Xia, Ruiguang Zhang, Fan Tong, Xiaorong Dong
Publikováno v:
Cancer Communications, Vol 43, Iss 5, Pp 625-629 (2023)
Externí odkaz:
https://doaj.org/article/25375e8ebf144ab78f99ce2c020c672d