Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Xiaoran Han"'
Autor:
Xiaojie Wu, Jicheng Yu, Beikang Ge, Jeffrey Wang, Xiaoran Han, Chunye Zhang, Xiaomeng Mao, Hindu Kalluru, Candace Bramson, Steven G. Terra, Jing Liu
Publikováno v:
Drugs in R&D, Vol 24, Iss 2, Pp 253-262 (2024)
Abstract Background Vupanorsen is a GalNAc3-conjugated antisense oligonucleotide targeting angiopoietin-like 3 (ANGPTL3) mRNA shown to reduce atherogenic lipoproteins in individuals with dyslipidemia. Objectives The aim of this study was to satisfy C
Externí odkaz:
https://doaj.org/article/10d247a2976c43c09756cc2d0d3d6245
Autor:
Xiang Cheng, Xiaoran Han, Jia Si, Cong Dong, Zhongjuan Ji, Shicong Zhao, Xiangting Wu, Haiyan Li, Xiangqun Jin
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1155 (2024)
Curcumin, a naturally occurring poorly water-soluble polyphenol with a broad spectrum, is a typical BCS IV drug. The objective of this study was to develop curcumin nanocrystals liposomes with the aim of improving bioavailability. In this study, we p
Externí odkaz:
https://doaj.org/article/a9e5d46cbe5a401fb502a0e0a0610c73
Publikováno v:
Ecological Indicators, Vol 144, Iss , Pp 109492- (2022)
The rapid expansion of invasive Spartina alterniflora in China’s coastal wetlands has seriously threatened regional ecosystem health. Characterizing phenology of S. alterniflora salt marshes supports the studies on plant invasion mechanism and carb
Externí odkaz:
https://doaj.org/article/57c4dc672c3c44729bbd07b4032ed6d8
Autor:
Tao Zhang, Kangyun Dong, Wei Liang, Daichao Xu, Hongguang Xia, Jiefei Geng, Ayaz Najafov, Min Liu, Yanxia Li, Xiaoran Han, Juan Xiao, Zhenzhen Jin, Ting Peng, Yang Gao, Yu Cai, Chunting Qi, Qing Zhang, Anyang Sun, Marta Lipinski, Hong Zhu, Yue Xiong, Pier Paolo Pandolfi, He Li, Qiang Yu, Junying Yuan
Publikováno v:
eLife, Vol 4 (2015)
Autophagy is an important intracellular catabolic mechanism involved in the removal of misfolded proteins. Atg14L, the mammalian ortholog of Atg14 in yeast and a critical regulator of autophagy, mediates the production PtdIns3P to initiate the format
Externí odkaz:
https://doaj.org/article/3e868138a8c44057ad78966bdd7397e1
Autor:
Yan Xiong, Yue Zhong, Hyerin Yim, Xiaobao Yang, Kwang-Su Park, Ling Xie, Poulikos I. Poulikakos, Xiaoran Han, Yue Xiong, Xian Chen, Jing Liu, Jian Jin
Publikováno v:
J Am Chem Soc
Proteolysis Targeting Chimeras (PROTACs) are attractive therapeutic modalities for degrading disease-causing proteins. While many PROTACs have been developed for numerous protein targets, current small-molecule PROTAC approaches cannot target undrugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ee42491f14c4a05e0bf13aea03eb46
https://doi.org/10.1021/jacs.2c09255
https://doi.org/10.1021/jacs.2c09255
Publikováno v:
ISA Transactions. 129:73-87
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eee1c4f41981aa74a90f189563a9a78
https://doi.org/10.1016/j.isatra.2022.02.025
https://doi.org/10.1016/j.isatra.2022.02.025
Publikováno v:
International Journal of Robust and Nonlinear Control. 31:9231-9252
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2138ce007f99099d5884d7e900d67cc4
https://doi.org/10.1002/rnc.5763
https://doi.org/10.1002/rnc.5763
Autor:
Harun Tugal, Kamil Cetin, Xiaoran Han, Ibrahim Kucukdemiral, Joshua Roe, Yvan Petillot, M. Suphi Erden
Publikováno v:
2022 International Conference on Robotics and Automation (ICRA).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e48872dd57c5f4291b966521f9f045f7
https://doi.org/10.1109/icra46639.2022.9812005
https://doi.org/10.1109/icra46639.2022.9812005
Autor:
Matthew R. Lee, Yang Xu, Chao Zhang, Weihua Yu, Liqun Chen, Bingyang Jiao, Ying Luo, Plewe Michael Bruno, Lei Sun, Jialiang Wang, Yanke Chen, Yuanqi Wei, Tingting Shi, Xiaoran Han, Chunyan Zhang
Publikováno v:
Journal of Medicinal Chemistry. 63:4069-4080
BRAF is among the most frequently mutated oncogenes in human cancers. Multiple small molecule BRAF kinase inhibitors have been approved for treating melanoma carrying BRAF-V600 mutations. However, the benefits of BRAF kinase inhibitors are generally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2586af92b5726ce90909b4bef8cc5798
https://doi.org/10.1021/acs.jmedchem.9b02083
https://doi.org/10.1021/acs.jmedchem.9b02083
Autor:
Jing Liu, Yue Xiong, Ling Xie, Xufen Yu, Xiaoran Han, Meng Cheng, Jian Jin, Fanye Meng, Li Wang, Xian Chen, Kaylene Lu
Publikováno v:
J Med Chem
Several epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors have been developed and approved by Food and Drug Administration for the treatment of non-small-cell lung cancers, but their efficacy can be compromised by acquired drug resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e596f71e4373e004cd86666ea07705d5
https://doi.org/10.1021/acs.jmedchem.9b01566
https://doi.org/10.1021/acs.jmedchem.9b01566