Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Xiaoqun Gao"'
Publikováno v:
Analytical Cellular Pathology, Vol 2022 (2022)
Alzheimer’s disease (AD) is one common degenerative disorder. However, the effects of miR-590-5p on AD and the mechanism on modulation of AD development were unclear. In this study, the miR-590-5p level in AD patients at mild, moderate, and severe
Externí odkaz:
https://doaj.org/article/dcc43bb0e5b14126b4deeb683aa466e6
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33722 (2012)
The dementia of Alzheimer's type and brain ischemia are known to increase at comparable rates with age. Recent advances suggest that cerebral ischemia may contribute to the pathogenesis of Alzheimer's disease (AD), however, the neuropathological rela
Externí odkaz:
https://doaj.org/article/20109568f2dd4655a2b717fd7aa6aa92
Publikováno v:
BioMed Research International. 2022:1-11
Neuroglobin is an oxygen-binding heme protein expressed predominantly in the brain. Despite many years of research, the exact distribution and expression of neuroglobin in the neocortical development and under mild hypoxia stress still remain unclear
Publikováno v:
Journal of Alzheimer's Disease. 72:83-96
Brain energy metabolic impairment is one of the main features of Alzheimer's disease (AD) and is considered an underlying factor involved in cognitive impairment. Therefore, brain energy metabolism may represent a new therapeutic target for AD medica
Publikováno v:
Analytical cellular pathology (Amsterdam). 2022
Alzheimer's disease (AD) is one common degenerative disorder. However, the effects of miR-590-5p on AD and the mechanism on modulation of AD development were unclear. In this study, the miR-590-5p level in AD patients at mild, moderate, and severe st
Autor:
Xiaofan Wang, Xiaoqun Gao, Yingnan Peng, Ruiqi Pang, Xupeng Lu, Zhiqiang Du, Feifei Pei, Cheng Chang, Shuying Wang, Libing Sun, Zhiyue Li
Publikováno v:
J Anat
Monocarboxylates cannot cross the blood-brain barrier freely to participate in brain energy metabolism. Specific monocarboxylate transporters (MCTs) are needed to cross cellular membranes. Monocarboxylate transporter 2 (MCT2) is a major monocarboxyla
Autor:
Qinying Cui, Yanfen Wang, Junxia Zhang, Xiaodong Li, Ge Gao, Qiang Zhou, Xiaoqun Gao, Yuping Xu
Publikováno v:
Molecular Medicine Reports
Malignant gliomas are the most common type of primary malignancy of the central nervous system, with a poor prognosis. The therapeutic options for malignant gliomas are limited and far from satisfactory, and novel treatment strategies are urgently re
Autor:
Yanfen Wang, Guanlin Li, Lingfei Kong, Qiang Zhou, Xiaoqun Gao, Ge Gao, Ying Xing, Mengfei Yu, Junxia Zhang, Zhihui Fang
Publikováno v:
OncoTargets and therapy
Junxia Zhang,1,* Qiang Zhou,2,* Ge Gao,3,* Yanfen Wang,1 Zhihui Fang,1 Guanlin Li,4 Mengfei Yu,5 Lingfei Kong,6 Ying Xing,3 Xiaoqun Gao11Department of Anatomy, Basic Medical College, Zhengzhou University, Henan, People’s Republic of China; 2Departm
Autor:
Zhixin, Wang, Tongxing, Deng, Jiexin, Deng, Jinbo, Deng, Xiaoqun, Gao, Yuanyuan, Shi, Bin, Liu, Zhanyou, Ma, Haixiao, Jin
Publikováno v:
Neural Regeneration Research
Prenatal alcohol exposure, especially during early pregnancy, can lead to fetal alcohol syndrome. The pharmacological and toxicological mechanisms of ethanol are related to the effects of ceramide. In this study, we established an alcohol exposure mo
Publikováno v:
Neural Regeneration Research
Previous studies showed that tyrosine hydroxylase or neurturin gene-modified cells transplanted into rats with Parkinson’s disease significantly improved behavior and increased striatal dopamine content. In the present study, we transplanted tyrosi