Zobrazeno 1 - 10
of 560
pro vyhledávání: '"Xiaoquan WANG"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Many DNA viruses develop various strategies to inhibit cell death to facilitate their replication. However, whether influenza A virus (IAV), a fast-replicating RNA virus, attenuates cell death remains unknown. Here, we report that IAV infect
Externí odkaz:
https://doaj.org/article/2ab463230aee4676807d10cad6331be4
Autor:
Xiaoquan Wang, Xin-en Tang, Huafen Zheng, Ruyi Gao, Xiaolong Lu, Wenhao Yang, Le Zhou, Yu Chen, Min Gu, Jiao Hu, Xiaowen Liu, Shunlin Hu, Kaituo Liu, Xiufan Liu
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-11 (2024)
Abstract H7N9 subtype avian influenza viruses (AIVs) cause 1567 human infections and have high mortality, posing a significant threat to public health. Previously, we reported that two avian-derived H7N9 isolates (A/chicken/Eastern China/JTC4/2013 an
Externí odkaz:
https://doaj.org/article/715ba77da2d44e409ec236362c520ee3
Autor:
Xiaolong Lu, Tiansong Zhan, Qiwen Zhou, Wenhao Yang, Kaituo Liu, Yu Chen, Ruyi Gao, Jiao Hu, Min Gu, Shunlin Hu, Xin-an Jiao, Xiaoquan Wang, Xiufan Liu, Xiaowen Liu
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-15 (2024)
Abstract The haemagglutinin–neuraminidase (HN) protein, a vital membrane glycoprotein, plays a pivotal role in the pathogenesis of Newcastle disease virus (NDV). Previously, we demonstrated that a mutation in the HN protein is essential for the enh
Externí odkaz:
https://doaj.org/article/4a616a62424f496e9418566fe263020e
Autor:
Dongchang He, Xiyue Wang, Huiguang Wu, Kairui Cai, Xiaoli Song, Xiaoquan Wang, Jiao Hu, Shunlin Hu, Xiaowen Liu, Chan Ding, Daxin Peng, Shuo Su, Min Gu, Xiufan Liu
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
Vaccination is crucial for the prevention and mitigation of avian influenza infections in China. The inactivated H7N9 vaccine, when administered to poultry, significantly lowers the risk of infection among both poultry and humans, while also markedly
Externí odkaz:
https://doaj.org/article/a7b9e2a73e3244e28a17ea0d850ad24b
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
ABSTRACTNewcastle disease virus (NDV) typically induces severe illness in poultry and results in significant economic losses for the worldwide poultry sector. NDV, an RNA virus with a single-stranded negative-sense genome, is susceptible to mutation
Externí odkaz:
https://doaj.org/article/283aebc8d65b4755ab4d00b9d2f0c8b4
Autor:
Jingting Zhang, Yunhan Wu, Yujie Wang, Penggang Liu, Kaituo Liu, Jing Sun, Pinghu Zhang, Xiaoquan Wang, Xiufan Liu, Xiulong Xu
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110424- (2024)
Summary: Cellular cholesterol plays an important role in influenza A virus (IAV) endocytosis and replication. However, how IAV infection regulates cholesterol biosynthesis remains poorly understood. Here, we report that IAV infection activates SREBP2
Externí odkaz:
https://doaj.org/article/a0a649b0acbc4915bad27ec73ba7ca25
Publikováno v:
Veterinary Quarterly, Vol 43, Iss 1, Pp 1-14 (2023)
AbstractInfluenza A virus is a negative-sense single-stranded RNA virus that belongs to Orthomyxoviridae family. Based on the antigenic characteristics of hemagglutinin (HA) and neuraminidase (NA) influenza viruses are classified into multiple subtyp
Externí odkaz:
https://doaj.org/article/97f5a0d7546c40c7b16b1fdf10518986
Autor:
Xiaolong Lu, Kaituo Liu, Yu Chen, Ruyi Gao, Zenglei Hu, Jiao Hu, Min Gu, Shunlin Hu, Chan Ding, Xinan Jiao, Xiaoquan Wang, Xiufan Liu, Xiaowen Liu
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-17 (2023)
Abstract The haemagglutinin-neuraminidase (HN) protein plays a crucial role in the infectivity and virulence of Newcastle disease virus (NDV). In a previous study, the mutant HN protein was identified as a crucial virulence factor for the velogenic v
Externí odkaz:
https://doaj.org/article/87bd018d1cad4bb7a588b43e8cb2dd13
Autor:
Xiaoquan Wang, Youqiao Wang, Anqi Cao, Qinhong Luo, Daoyuan Chen, Weiqi Zhao, Jun Xu, Qinkai Li, Xianzhang Bu, Junmin Quan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Cyclic GMP-AMP synthase (cGAS) is an essential sensor of aberrant cytosolic DNA for initiating innate immunity upon invading pathogens and cellular stress, which is considered as a potential drug target for autoimmune and autoinflammatory di
Externí odkaz:
https://doaj.org/article/368695835d6647a4a7fbd4a058fe58e3
Publikováno v:
Applied Sciences, Vol 14, Iss 17, p 7590 (2024)
The stability problem of high fill slopes has always been a research hotspot. Its failure mechanism is complex and prominent, featuring strong concealment, a short occurrence time and great harmfulness. In this paper, the stability of a high fill slo
Externí odkaz:
https://doaj.org/article/41b4527f60ac408b85066d680a08c34c