Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Xiaoqiong Hou"'
Autor:
Shenxia Xie, Wei Shi, Siliang Duan, Xianing Huang, Aiqun Liu, Xiaoqiong Hou, Xuandong Lin, Dani Zhong, Shuyang Sun, Ziqiang Ding, Xiaomei Yang, Xiaoyuan Chen, Xiaoling Lu
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background T cell-based immunotherapies are facing great challenges in the recruitment and activation of tumor-specific T cells against solid tumors. Among which, utilizing nanobody (Nb) or nanobodies (Nbs) to construct T cell engager has em
Externí odkaz:
https://doaj.org/article/34819bd0e84d4974b541afced7e0be7f
Autor:
Qihui Wang, Zihe Liu, Xia Zeng, Yu Zheng, Li Lan, Xinhang Wang, Zhenping Lai, Xiaoqiong Hou, Lingxi Gao, Liang Liang, Shen Tang, Zengfeng Zhang, Jing Leng, Xiaohui Fan
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Background Cross-species transmission of zoonotic IAVs to humans is potentially widespread and lethal, posing a great threat to human health, and their cross-species transmission mechanism has attracted much attention. miRNAs have been shown
Externí odkaz:
https://doaj.org/article/4c35e788da164580a8fc8ef4a9525458
Autor:
Ziqiang Ding, Shuyang Sun, Xuan Wang, Xiaomei Yang, Wei Shi, Xianing Huang, Shenxia Xie, Fengzhen Mo, Xiaoqiong Hou, Aiqun Liu, Xiaobing Jiang, Zhuoran Tang, Xiaoling Lu
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-20 (2023)
Abstract Background T cell engagers (TCEs) have been established as an emerging modality for hematologic malignancies, but solid tumors remain refractory. However, the upregulation of programmed cell death 1 (PD-1) is correlated with T cell dysfuncti
Externí odkaz:
https://doaj.org/article/d7cf21ab350043c3a55e1d6c78ecd683
Autor:
Fengzhen Mo, Siliang Duan, Xiaobing Jiang, Xiaomei Yang, Xiaoqiong Hou, Wei Shi, Cueva Jumbo Juan Carlos, Aiqun Liu, Shihua Yin, Wu Wang, Hua Yao, Zihang Yu, Zhuoran Tang, Shenxia Xie, Ziqiang Ding, Xinyue Zhao, Bruce D. Hammock, Xiaoling Lu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Chimeric antigen receptor-based T-cell immunotherapy is a promising strategy for treatment of hematological malignant tumors; however, its efficacy towards solid cancer remains challenging. We therefore focused on developing nanobody-based C
Externí odkaz:
https://doaj.org/article/0467899002724f14b4216f34d0b7aa35
Autor:
Lichen Zhu, Xiaomei Yang, Dani Zhong, Shenxia Xie, Wei Shi, Yangzi Li, Xiaoqiong Hou, HuaYao, Huihui Zhou, Minlong Zhao, Ziqiang Ding, Xinyue Zhao, Fengzhen Mo, Shihua Yin, Aiqun Liu, Xiaoling Lu
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
Retargeting the antigen-binding specificity of T cells to intracellular antigens that are degraded and presented on the tumor surface by engineering chimeric antigen receptor (CAR), also named TCR-like antibody CAR-T, remains limited. With the except
Externí odkaz:
https://doaj.org/article/c63e1f7f861a46d5bcea752b80cbcf57
Autor:
Qihui Wang, Xia Zeng, Shen Tang, Li Lan, Xinhang Wang, Zhenping Lai, Zihe Liu, Xiaoqiong Hou, Lingxi Gao, Chenxia Yun, Zengfeng Zhang, Jing Leng, Xiaohui Fan
Publikováno v:
Virus research.
Animal influenza viruses can spread across species and pose a fatal threat to human health due to the high pathogenicity and mortality. Animal models are crucial for studying cross-species infection and the pathogenesis of influenza viruses. Tupaia b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3886b13162efeca9fd8855bf97098c
https://pubmed.ncbi.nlm.nih.gov/36543317
https://pubmed.ncbi.nlm.nih.gov/36543317
Autor:
Xiaoqiong Hou, Xiaoling Lu, Ziqiang Ding, Dujin Wang, Fengzhen Mo, Xiaomei Yang, Ai Qun Liu, Wei Shi, Duan Siliang
Publikováno v:
International Journal of Nanomedicine. 15:8383-8400
Purpose Cancer tissue-specific and nuclei-targeted drug delivery is ideal for the delivery of chemotherapy. However, it has only been achieved in in vitro studies mainly due to low efficiency in vivo. In this study, we aimed to establish an efficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c46774e765c890d01caf5fdfbaf2b328
https://doi.org/10.2147/ijn.s272495
https://doi.org/10.2147/ijn.s272495
Autor:
Shenxia Xie, Fengzhen Mo, Ai Qun Liu, Xiaoling Lu, Shi Wei, Xiaoqiong Hou, Zhengui Peng, Xiaomei Yang, Yangzi Li, Chunhui Lai, Xinyue Zhao, Ziqiang Ding, Hua Yao
Publikováno v:
Journal of Biomedical Nanotechnology. 16:1119-1134
In this research, we studied the therapeutic efficacy of a newly designed fusion protein containing Endoglin single-chain variable fragment and IP10 (Endoglin-scFv/IP10), together with our recently generated TRP2-specific CD8+ CD28+ CTLs (CD8+ CD28+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baaf250713a9df08732ce144277792a0
https://doi.org/10.1166/jbn.2020.2949
https://doi.org/10.1166/jbn.2020.2949
Autor:
Xiaobing Jiang, Bogdan Barnych, Xiaomei Yang, Jie-Xian Dong, Bruce D. Hammock, Ai Qun Liu, Duan Siliang, Fengzhen Mo, Xiaoqiong Hou, Xiaoling Lu, Liu Liang, Zhuoran Tang, Natalia Vasylieva, Shihua Yin
Publikováno v:
J Biomed Nanotechnol
Adoptive cell-based immunotherapy typically utilizes cytotoxic T lymphocytes (CTLs), expanding these cells ex vivo. Such expansion is traditionally accomplished through the use of autologous APCs that are capable of interactions with T cells. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3baa5f7908e5e0613971312e9c5cdcdc
https://doi.org/10.1166/jbn.2019.2859
https://doi.org/10.1166/jbn.2019.2859
Autor:
Wu Wang, Fengzhen Mo, Xiaoling Lu, Ai Qun Liu, Shihua Yin, Xiaoqiong Hou, Zhuoran Tang, Xiaomei Yang
Publikováno v:
Oncology Letters
The detection of cytotoxic T-lymphocyte antigen-4-positive (CTLA-4+) T-cell subgroups in peripheral blood samples and tumor tissues is of great significance. In the present study, a rapid, succinct and efficient method was designed for the detection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb07d3c892bee432c7a87f96f03be07
http://europepmc.org/articles/PMC6540141
http://europepmc.org/articles/PMC6540141