Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Xiaoqing Yao"'
Autor:
Jinmei Sun, Fengbo Xing, Jingjing Feng, Xin Chen, Lingling Lv, Xiaoqing Yao, Mengqi Wang, Ziye Zhao, Qian Zhou, Tingting Liu, Yuqian Zhan, Gong-Jun JI, Kai Wang, Panpan Hu
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32799- (2024)
Background: Repetitive transcranial magnetic stimulation (rTMS) is an effective noninvasive neuromodulation technique for Parkinson's disease (PD). However, the efficacy of rTMS varies widely between individuals. This study aimed to investigate the f
Externí odkaz:
https://doaj.org/article/ac0a962cf0c04ad9a81791000dfa87b1
Autor:
Qiu Tu, Xiuyun Liu, Xiaoqing Yao, Ruixue Li, Gaojing Liu, Honglv Jiang, Kaiqin Li, Qiongfang Chen, Xiaoyan Huang, Qing Chang, Guoqiang Xu, Hong Zhu, Peng Shi, Bo Zhao
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-22 (2022)
Abstract Background Severe hypoxia is a prominent character of pancreatic ductal adenocarcinoma (PDAC) microenvironment. In the process of gemcitabine based chemotherapy, PDAC cells are insulted from replication stresses co-induced by hypoxia and gem
Externí odkaz:
https://doaj.org/article/66e2c0f5f2b841ab9da4037fa74905fe
Autor:
Fangfang Lai, Ming Ji, Lei Huang, Yunchen Wang, Nina Xue, Tingting Du, Kai Dong, Xiaoqing Yao, Jing Jin, Zhiqiang Feng, Xiaoguang Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 6, Pp 2845-2858 (2022)
PD-1 and PD-L1 antibodies have brought about extraordinary clinical benefits for cancer patients, and their indications are expanding incessantly. Currently, most PD-1/PD-L1 agents are administered intravenously, which may be uncomfortable for some c
Externí odkaz:
https://doaj.org/article/424e1258b7794af9ac057be489c0fcc9
Autor:
Fangfang Lai, Ming Ji, Lei Huang, Yunchen Wang, Nina Xue, Tingting Du, Kai Dong, Xiaoqing Yao, Jing Jin, Zhiqiang Feng, Xiaoguang Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 7, Pp 3178-3179 (2023)
Externí odkaz:
https://doaj.org/article/29436e72a23f4f63b09793755c106b05
Autor:
Chi Zhang, Xiaoqing Yao, Yan Zhang, Shengbo Zhao, Jinghui Liu, Gang Wu, Xiaohong Yan, Junling Luo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10641 (2023)
BnSIP1-1 is the first identified SIP1 (6b Interacting Protein1) subfamily gene of the trihelix transcription factor family from Brassica napus (B. napus). We previously used a reverse genetic method to reveal its abiotic stress response function in e
Externí odkaz:
https://doaj.org/article/4463a9f690f54eff9e662a6fc30b7264
Publikováno v:
Materials, Vol 16, Iss 7, p 2786 (2023)
1,5-Anhydroglucitol (1,5-AG) is a sensitive biomarker for real-time detection of diabetes mellitus. In this study, an electrochemical biosensor to specifically detect 1,5-AG levels based on persimmon-tannin-reduced graphene oxide-PtPd nanocomposites
Externí odkaz:
https://doaj.org/article/43906d8590ea4a88aed115be9e63eea2
Publikováno v:
Toxics, Vol 10, Iss 10, p 580 (2022)
The sources of potentially toxic elements (PTEs) in road dust are complex and potentially harmful to humans, especially in industrial cities. Jiayuguan is the largest steel-producing city in Northwest China, and this study was the first to conduct a
Externí odkaz:
https://doaj.org/article/483bbe0d8c8847e6aa45baf1f3f4c689
Autor:
Jianwei Jiang, Xiaowen Zou, Yuke Liu, Xiao Liu, Kai Dong, Xiaoqing Yao, Zhiqiang Feng, Xiaoguang Chen, Li Sheng, Yan Li
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
IMMH-010 is a prodrug of YPD-29B, which is a novel PD-L1 inhibitor. A specific and sensitive LC-MS/MS method with polarity switching was developed and validated for the simultaneous determination of IMMH-010 and YPD-29B in rat plasma, liver, brain, u
Externí odkaz:
https://doaj.org/article/828e3e27909b4146926c8e64e6a61373
Autor:
Yuchen Wang, Xiao Liu, Xiaowen Zou, Shuting Wang, Lijun Luo, Yuke Liu, Kai Dong, Xiaoqing Yao, Yan Li, Xiaoguang Chen, Li Sheng
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 598 (2021)
IMMH-010 is an ester prodrug of YPD-29B, a potent programmed cell death ligand 1 (PD-L1) inhibitor. The metabolism of IMMH-010 was investigated and compared in various species. Four metabolites of IMMH-010 were identified, and the major metabolite wa
Externí odkaz:
https://doaj.org/article/fda292145959400c91ba0a20b7c62ba2
Publikováno v:
Journal of Biomedical Nanotechnology. 18:2484-2497
Golgi protein 73 (GP73) is a novel biomarker for the detection of hepatocellular carcinoma. We prepare a colorimetric aptasensor for GP73 detection based on the catalytic performance of the H-rGO-Mn3O4 nanozyme. The H-rGO-Mn3O4 nanozyme serves as a p