Zobrazeno 1 - 10
of 526
pro vyhledávání: '"Xiaoping Su"'
Autor:
Christopher P. Mill, Warren C. Fiskus, Courtney D. DiNardo, Patrick Reville, John A. Davis, Christine E. Birdwell, Kaberi Das, Hanxi Hou, Koichi Takahashi, Lauren Flores, Xinjia Ruan, Xiaoping Su, Sanam Loghavi, Joseph D. Khoury, Kapil N. Bhalla
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Germline, mono-allelic mutations in RUNX1 cause familial platelet disorder (RUNX1-FPD) that evolves into myeloid malignancy (FPD-MM): MDS or AML. FPD-MM commonly harbors co-mutations in the second RUNX1 allele and/or other epigenetic regulat
Externí odkaz:
https://doaj.org/article/b9424549a1ed49b58740fad27c6be69c
Autor:
Xiaoping Su, Xiaofan Lu, Sehrish Khan Bazai, Linda Dainese, Arnauld Verschuur, Benoit Dumont, Roger Mouawad, Li Xu, Wenxuan Cheng, Fangrong Yan, Sabine Irtan, Véronique Lindner, Catherine Paillard, Yves Le Bouc, Aurore Coulomb, Gabriel G. Malouf
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Wilms tumors are highly curable in up to 90% of cases with a combination of surgery and radio-chemotherapy, but treatment-resistant types such as diffuse anaplastic Wilms tumors pose significant therapeutic challenges. Our multi-omics profil
Externí odkaz:
https://doaj.org/article/04f4843568a140c78ff076e8570ab074
Autor:
Chang Sun, Yuan Qi, Natalie Fowlkes, Nina Lazic, Xiaoping Su, Guillermina Lozano, Amanda R. Wasylishen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-9 (2023)
Abstract Daxx functions as a histone chaperone for the histone H3 variant, H3.3, and is essential for embryonic development. Daxx interacts with Atrx to form a protein complex that deposits H3.3 into heterochromatic regions of the genome, including c
Externí odkaz:
https://doaj.org/article/a2b8e003959247d18bd59dc80dcac901
Autor:
Bujamin H. Vokshi, Guillaume Davidson, Nassim Tawanaie Pour Sedehi, Alexandra Helleux, Marc Rippinger, Alexandre R. Haller, Justine Gantzer, Jonathan Thouvenin, Philippe Baltzinger, Rachida Bouarich, Valeria Manriquez, Sakina Zaidi, Priya Rao, Pavlos Msaouel, Xiaoping Su, Hervé Lang, Thibault Tricard, Véronique Lindner, Didier Surdez, Jean-Emmanuel Kurtz, Franck Bourdeaut, Nizar M. Tannir, Irwin Davidson, Gabriel G. Malouf
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Renal medullary carcinoma (RMC) is an aggressive tumour driven by bi-allelic loss of SMARCB1 and tightly associated with sickle cell trait. However, the cell-of-origin and oncogenic mechanism remain poorly understood. Using single-cell seque
Externí odkaz:
https://doaj.org/article/01f90a34514d4d2a88792568e2a609ad
Autor:
Xiaoping Su, Xiangtong Wang, Ning Li, Longjian Li, Yilare Tuerhong, Yongchong Yu, Zhichao Wang, Tao Shen, Qiong Su, Ping Zhang
Publikováno v:
Molecules, Vol 29, Iss 9, p 1948 (2024)
It is very important to choose a suitable method and catalyst to treat coking wastewater. In this study, Fe–Ce–Al/MMT catalysts with different Fe/Ce molar ratios were prepared, characterized by XRD, SEM, and N2 adsorption/desorption, and treated
Externí odkaz:
https://doaj.org/article/59f2526af0af4b61b4b93a3b66856afa
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-22 (2023)
Abstract Neoantigens generated by non-synonymous mutations of tumor genes can induce activation of neoantigen-reactive T (NRT) cells which have the ability to resist the growth of tumors expressing specific neoantigens. Immunotherapy based on NRT cel
Externí odkaz:
https://doaj.org/article/f1d5347f2f26465a9b0839c3c89141a5
Autor:
Warren Fiskus, Christopher P. Mill, Christine Birdwell, John A. Davis, Kaberi Das, Steffen Boettcher, Tapan M. Kadia, Courtney D. DiNardo, Koichi Takahashi, Sanam Loghavi, Michael J. Soth, Tim Heffernan, Gerard M. McGeehan, Xinjia Ruan, Xiaoping Su, Christopher R. Vakoc, Naval Daver, Kapil N. Bhalla
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Monotherapy with Menin inhibitor (MI), e.g., SNDX-5613, induces clinical remissions in patients with relapsed/refractory AML harboring MLL1-r or mtNPM1, but most patients either fail to respond or eventually relapse. Utilizing single-cell RN
Externí odkaz:
https://doaj.org/article/ac5251edf70f45ea8914536e1354701b
Publikováno v:
AIP Advances, Vol 13, Iss 10, Pp 105223-105223-19 (2023)
In this study, a series of Fe–Ce–Al/MMT catalysts were prepared, characterized by XRD, SEM and N2 adsorption/desorption, and treated with phenol-containing wastewater. The results showed that the optimal Fe–Ce–Al/MMT catalyst with a molar rat
Externí odkaz:
https://doaj.org/article/acd2c06446bf474ca1d0b155c29f1349
Autor:
Brandon Mistretta, Sakuni Rankothgedera, Micah Castillo, Mitchell Rao, Kimberly Holloway, Anjana Bhardwaj, Maha El Noafal, Constance Albarracin, Randa El-Zein, Hengameh Rezaei, Xiaoping Su, Rehan Akbani, Xiaoshan M. Shao, Brian J. Czerniecki, Rachel Karchin, Isabelle Bedrosian, Preethi H. Gunaratne
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionWe present here a strategy to identify immunogenic neoantigen candidates from unique amino acid sequences at the junctions of fusion proteins which can serve as targets in the development of tumor vaccines for the treatment of breastcance
Externí odkaz:
https://doaj.org/article/4ec9e2ca15084d978b27a5af1c2c1793
Autor:
Xiaoping Su, Gabriel Malouf
Publikováno v:
HemaSphere, Vol 7, p e656824a (2023)
Externí odkaz:
https://doaj.org/article/9b46340be2ae419fbeb1b3f9ef384ed3