Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Xiaopin Duan"'
Autor:
Jinmei Cheng, Jiaxin Li, Qilin Yu, Peishan Li, Junyi Huang, Jinhui Li, Leyang Guan, Zhiyong Xu, Jisheng Xiao, Xiaopin Duan
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Chemotherapy, as a conventional strategy for tumor therapy, often leads to unsatisfied therapeutic effect due to the multi-drug resistance and the serious side effects. Herein, we genetically engineered a thermal-responsive murine Ferritin (
Externí odkaz:
https://doaj.org/article/3ce009afe81541a692e9ae88e63580ba
Autor:
Xiaobo Wang, Chengyuan Cai, Weiqi Lv, Kechen Chen, Jiaxin Li, Kaitong Liao, Yanqun Zhang, Hongxin Huang, Ying Lin, Zhili Rong, Xiaopin Duan
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract CRISPR-based gene therapy offers precise targeting and specific editing of disease-related gene sequences, potentially yielding long-lasting treatment effects. However, efficient delivery remains a significant challenge for its widespread ap
Externí odkaz:
https://doaj.org/article/243debc11d674ee4890ae100ab1fb676
Autor:
Jing Yang, Wei Xiong, Lin Huang, Zongheng Li, Qingdeng Fan, Fang Hu, Xiaopin Duan, Junbing Fan, Bo Li, Jie Feng, Yikai Xu, Xiaoyuan Chen, Zheyu Shen
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract As a famous drug delivery system (DDS), mesoporous organosilica nanoparticles (MON) are degraded slowly in vivo and the degraded components are not useful for cell nutrition or cancer theranostics, and superparamagnetic iron oxide nanopartic
Externí odkaz:
https://doaj.org/article/91e93a70435f4ef5905158be114882dd
Autor:
Jinmei Cheng, Yushun Dou, Jiaxin Li, Tingting You, Yihai Wang, Mengchuan Wang, Shengjun Shi, Shenghui Peng, Chun-hui Cui, Xiaopin Duan, Jisheng Xiao
Publikováno v:
Materials & Design, Vol 238, Iss , Pp 112638- (2024)
Critical limb ischemia (CLI) remains a significant clinical challenge with high morbidity and mortality. Considering the critical role of hypoxia-inducible factor 1α (HIF-1α) in hypoxic site to induce angiogenesis by regulating the expression of gr
Externí odkaz:
https://doaj.org/article/e55002e844c940e082d2da807e531950
Autor:
Jisheng Xiao, Haishan Li, Wanling Zhao, Chengyuan Cai, Tingting You, Zhenyu Wang, Mengling Wang, Feng Zeng, Jinmei Cheng, Jiaxin Li, Xiaopin Duan
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background UV exposure continues to induce many health issues, though commercial sunscreens are available. Novel UV filters with high safety and efficacy are urgently needed. Metal–organic frameworks (MOFs) could be a suitable platform for
Externí odkaz:
https://doaj.org/article/2b5cc8959d404a049562dbca87a17641
Publikováno v:
Medicine in Drug Discovery, Vol 15, Iss , Pp 100139- (2022)
As a “marker of self”, CD47 is expressed on the surface of all cells in humans, mice, and other mammals to inhibit phagocytic destruction of normal cells through interacting with signal regulatory protein α (SIRPα) on the macrophages and dendri
Externí odkaz:
https://doaj.org/article/21177ee2d8f54067b200ca80cdbca889
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nanoparticles can stimulate tumour microenvironment to promote anti-tumour immunity. Here, the authors show that the combination of delivering drugs by a nanoscale coordination polymer and anti-PD-L1 is synergistic in treating murine colorectal cance
Externí odkaz:
https://doaj.org/article/32d406d04174474cb36aa4ac0dbdafaa
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Photosensitizers delivered to mitochondria of cancer cells can enhance photodynamic therapy. Here, the authors report mitochondria-targeted radiation therapy and radiodynamic therapy of colorectal cancer models with a cationic nanoscale metal-organic
Externí odkaz:
https://doaj.org/article/b48e9debae774852a0d394aca2141437
Autor:
Chunbai He, Xiaopin Duan, Nining Guo, Christina Chan, Christopher Poon, Ralph R. Weichselbaum, Wenbin Lin
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Blockade of PD-L1 is usually not very effective in colon cancer patients. Here, the authors show the efficacy of PD-L1 blockade in combination with coordination polymer nanoparticles carrying oxaliplatin and a photosensitizer to induce anti-tumor imm
Externí odkaz:
https://doaj.org/article/cba12bafd7ff4dc78c67844f9ae432d6
Autor:
Chengyuan Cai, Junqiao Zhu, Xiaobin Huang, Changda Xu, Zhenyu Wang, Tingting You, Xiao Wang, Jisheng Xiao, Xiaopin Duan
Publikováno v:
Advanced Functional Materials.