Zobrazeno 1 - 10
of 400
pro vyhledávání: '"Xiaopeng, Xu"'
Autor:
Jian-hui He, Deyu Han, Xianyu Meng, Lingling Li, Bangping Hu, Muting Yan, Zi-Ang Wang, Shaoping Weng, Jianguo He, Xiaopeng Xu
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-9 (2024)
Abstract The genus Megalocytivirus, belonging to the family Iridoviridae, is one of the most detrimental virus groups to fish aquaculture. Megalocytivirus creates a virus-mock basement membrane (VMBM) on the surface of infected cells. This membrane p
Externí odkaz:
https://doaj.org/article/9715526351294e14a092d480c4098699
Autor:
Lihua Chen, Nannan Wang, Tongran Zhang, Feng Zhang, Wei Zhang, Hao Meng, Jingyi Chen, Zhiying Liao, Xiaopeng Xu, Zhuo Ma, Tao Xu, Huisheng Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Dysfunction of pancreatic δ cells contributes to the etiology of diabetes. Despite their important role, human δ cells are scarce, limiting physiological studies and drug discovery targeting δ cells. To date, no directed δ-cell different
Externí odkaz:
https://doaj.org/article/b06189db468e4502a0d03752e4e92f11
Autor:
Haoyang Li, Yingxin Lin, Wenjia He, Wenkai Han, Xiaopeng Xu, Chencheng Xu, Elva Gao, Hongyu Zhao, Xin Gao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract With the flourishing of spatial omics technologies, alignment and stitching of slices becomes indispensable to decipher a holistic view of 3D molecular profile. However, existing alignment and stitching methods are unpractical to process lar
Externí odkaz:
https://doaj.org/article/062f0182d2a6493e8162a5ef22c1f709
Autor:
Juexiao Zhou, Bin Zhang, Guowei Li, Xiuying Chen, Haoyang Li, Xiaopeng Xu, Siyuan Chen, Wenjia He, Chencheng Xu, Liwei Liu, Xin Gao
Publikováno v:
Advanced Science, Vol 11, Iss 44, Pp n/a-n/a (2024)
Abstract With the fast‐growing and evolving omics data, the demand for streamlined and adaptable tools to handle bioinformatics analysis continues to grow. In response to this need, Automated Bioinformatics Analysis (AutoBA) is introduced, an auton
Externí odkaz:
https://doaj.org/article/ee72c6f9d6f34f2399c301e1acfd5f1f
Publikováno v:
Advanced Science, Vol 11, Iss 23, Pp n/a-n/a (2024)
Abstract Volatile solid additives have attracted increasing attention in optimizing the morphology and improving the performance of currently dominated non‐fullerene acceptor‐based organic solar cells (OSCs). However, the underlying principles go
Externí odkaz:
https://doaj.org/article/d5445fbe3ea34ea190ebd5104b8ff9b6
Autor:
Xiaopeng Xu, Tiantian Xu, Juexiao Zhou, Xingyu Liao, Ruochi Zhang, Yu Wang, Lu Zhang, Xin Gao
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 5, Pp 1043-1053 (2023)
Antibody leads must fulfill multiple desirable properties to be clinical candidates. Primarily due to the low throughput in the experimental procedure, the need for such multi-property optimization causes the bottleneck in preclinical antibody discov
Externí odkaz:
https://doaj.org/article/ebba8b9302554cf081b68e1f767e5be1
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-21 (2023)
Abstract Repetitive DNA sequences playing critical roles in driving evolution, inducing variation, and regulating gene expression. In this review, we summarized the definition, arrangement, and structural characteristics of repeats. Besides, we intro
Externí odkaz:
https://doaj.org/article/6d1798f49c454f13a4cc3069ab1deaff
Autor:
Xiaopeng Xu, Juexiao Zhou, Xin Gao, Yu Wang, Xingyu Liao, Zhongxiao Li, Ruochi Zhang, Chen Zhu, Qing Zhan
Publikováno v:
F1000Research, Vol 12 (2024)
Background The key challenge in drug discovery is to discover novel compounds with desirable properties. Among the properties, binding affinity to a target is one of the prerequisites and usually evaluated by molecular docking or quantitative structu
Externí odkaz:
https://doaj.org/article/58701ec4b4f14082ba5460b36cc5fa73
Autor:
Ke Mao, Christelle Borel, Muhammad Ansar, Angad Jolly, Periklis Makrythanasis, Christine Froehlich, Justyna Iwaszkiewicz, Bingqing Wang, Xiaopeng Xu, Qiang Li, Xavier Blanc, Hao Zhu, Qi Chen, Fujun Jin, Harinarayana Ankamreddy, Sunita Singh, Hongyuan Zhang, Xiaogang Wang, Peiwei Chen, Emmanuelle Ranza, Sohail Aziz Paracha, Syed Fahim Shah, Valentina Guida, Francesca Piceci-Sparascio, Daniela Melis, Bruno Dallapiccola, Maria Cristina Digilio, Antonio Novelli, Monia Magliozzi, Maria Teresa Fadda, Haley Streff, Keren Machol, Richard A. Lewis, Vincent Zoete, Gabriella Maria Squeo, Paolo Prontera, Giorgia Mancano, Giulia Gori, Milena Mariani, Angelo Selicorni, Stavroula Psoni, Helen Fryssira, Sofia Douzgou, Sandrine Marlin, Saskia Biskup, Alessandro De Luca, Giuseppe Merla, Shouqin Zhao, Timothy C. Cox, Andrew K. Groves, James R. Lupski, Qingguo Zhang, Yong-Biao Zhang, Stylianos E. Antonarakis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Craniofacial microsomia (CFM; also known as Goldenhar syndrome), is a craniofacial developmental disorder of variable expressivity and severity with a recognizable set of abnormalities. These birth defects are associated with structures deri
Externí odkaz:
https://doaj.org/article/1d57089cec0e40f9ac05f0b75d18ed43
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractDoxorubicin (DOX) is a commonly studied chemotherapeutic agent for the treatment of solid tumors, but the severe side effects limit its clinical application. It is shown that DOX-metal chelate has lower in vitro cytotoxicity compared with DOX
Externí odkaz:
https://doaj.org/article/83ea033f1db540cb9c49649dcf77e60f