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Akademický článek

Whole-exome sequencing in evaluation of patients with venous thromboembolism

Publikováno v: Blood Advances, Vol 1, Iss 16, Pp 1224-1237 (2017)

Abstract: Genetics play a significant role in venous thromboembolism (VTE), yet current clinical laboratory-based testing identifies a known heritable thrombophilia (factor V Leiden, prothrombin gene mutation G20210A, or a deficiency of protein C, pr

Externí odkaz: https://doaj.org/article/c274b1de27734d959984c4c6623722ac

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RESILIENT part 1: A phase 2 dose-exploration and dose-expansion study of second-line liposomal irinotecan in adults with small cell lung cancer

Autor: Luis Paz‐Ares, David R. Spigel, Yuanbin Chen, Maria Jove, Oscar Juan‐Vidal, Patricia Rich, Theresa Hayes, Vanesa Gutiérrez Calderón, Reyes Bernabe Caro, Alejandro Navarro, Afshin Dowlati, Bin Zhang, Yan Moore, Xiaopan Yao, Jaba Kokhreidze, Santiago Ponce, Paul A. Bunn

Publikováno v: CANCER
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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RESILIENT (NCT03088813) is a phase 2/3 study assessing the safety, tolerability, and efficacy of liposomal irinotecan monotherapy in patients with small cell lung cancer and disease progression on/after first-line platinum-based therapy. Here, we pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680d158944be2a7768767d9b0fb91f2a
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15599

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Akademický článek

A Common Polymorphism within the IGF2 Imprinting Control Region Is Associated with Parent of Origin Specific Effects in Infantile Hemangiomas.

Autor: Brent Schultz, Xiaopan Yao, Yanhong Deng, Milton Waner, Christopher Spock, Laura Tom, John Persing, Deepak Narayan

Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0113168 (2015)

Infantile hemangioma (IH) is the most common tumor of the pediatric age group, affecting up to 4% of newborns ranging from inconsequential blemishes, to highly aggressive tumors. Following well defined growth phases (proliferative, plateau involution

Externí odkaz: https://doaj.org/article/9855c22c710a4d5dbeeecdd7dc03693a

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Akademický článek

High SOX2 levels predict better outcome in non-small cell lung carcinomas.

Autor: Vamsidhar Velcheti, Kurt Schalper, Xiaopan Yao, Huan Cheng, Mehmet Kocoglu, Kavita Dhodapkar, Yanhong Deng, Scott Gettinger, David L Rimm

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e61427 (2013)

BACKGROUND: SOX2 is an embryonic developmental transcription factor, which is important in the development of the respiratory tract. SOX2 overexpression is associated with aggressive disease in several tumor types. However, SOX2 overexpression and ge

Externí odkaz: https://doaj.org/article/9750650890124d03991aafc84a2d4304

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Paraneoplastic Syndromes and Thymic Malignancies: An Examination of the International Thymic Malignancy Interest Group Retrospective Database

Autor: Frank C. Detterbeck, Joseph B. Shrager, Heather A. Wakelee, Sukhmani K. Padda, James Huang, Xiaopan Yao, Robert J. Korst, Sunil S. Badve, Bryan M. Burt, Alberto Antonicelli, Jonathan W. Riess, Yue Shang

Publikováno v: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, vol 13, iss 3

IntroductionThymic epithelial tumors (TETs) are associated with paraneoplastic/autoimmune (PN/AI) syndromes. Myasthenia gravis is the most common PN/AI syndrome associated with TETs.MethodsThe International Thymic Malignancy Interest Group retrospect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841fa57ac32a137c1af82a0ed7267a01
https://doi.org/10.1016/j.jtho.2017.11.118

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Leptin Is Produced by Parathyroid Glands and Stimulates Parathyroid Hormone Secretion

Autor: Samuel Kim, Glenda G. Callender, Derek Toomre, Nathalie Abitbol, Julie Ann Sosa, Xiaopan Yao, Felix Rivera-Molina, Alexander Y. Li, Fangyong Li, Niclas Broer, Sanziana A. Roman, Deepak Narayan, Christine A. Simpson, Gloria R. Sue, Don Hoang

Publikováno v: Annals of Surgery. 266:1075-1083

Objective We asked if leptin and its cognate receptor were present in normal and diseased parathyroid glands, and if so, whether they had any functional effects on parathyroid hormone (PTH) secretion in parathyroid neoplasms. Background The parathyro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5db3e67f4b633a7e06e7e9433ed820d
https://doi.org/10.1097/sla.0000000000002004

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Comparison of surgical approach and extent of resection for Masaoka-Koga Stage I and II thymic tumours in Europe, North America and Asia: an International Thymic Malignancy Interest Group retrospective database analysis†

Autor: Eric Vallières, Yue Shang, Brian E. Louie, Alberto Antonicelli, Ralph W. Aye, Alexander S. Farivar, Zhitao Gu, Wentao Fang, Frank C. Detterbeck, James Huang, Xiaopan Yao

Publikováno v: European Journal of Cardio-Thoracic Surgery. 52:26-32

OBJECTIVES Surgeons at different institutions worldwide choose different types of operations for thymic tumours. It is not known whether these differences affect the outcomes of the patients. METHODS A total of 1430 patients with Masaoka-Koga patholo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c36e40ea9f47d82ff140ef1f73ff15
https://doi.org/10.1093/ejcts/ezx042

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Postoperative Radiation Therapy Is Associated with Longer Overall Survival in Completely Resected Stage II and III Thymoma—An Analysis of the International Thymic Malignancies Interest Group Retrospective Database

Autor: Andreas Rimner, James Huang, Robert J. Korst, Daniel R. Gomez, Xiaopan Yao, Frank C. Detterbeck, Alberto Antonicelli, Usman Ahmad

Publikováno v: Journal of Thoracic Oncology. 11:1785-1792

Objectives The aim of this study was to determine whether postoperative radiation therapy (PORT) is associated with an overall survival (OS) benefit in patients with completely resected Masaoka or Masaoka-Koga stage II and III thymoma. Methods All pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2205cb66aeac373130a9ef0bfe625195
https://doi.org/10.1016/j.jtho.2016.06.011

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