Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Xiaoning Si"'
Autor:
Ying Qin, Lexun Lin, Yang Chen, Shuo Wu, Xiaoning Si, Heng Wu, Xia Zhai, Yan Wang, Lei Tong, Bo Pan, Xiaoyan Zhong, Tianying Wang, Wenran Zhao, Zhaohua Zhong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 4, Iss 4, Pp 284-294 (2014)
Human enterovirus 71 (EV71) is the main causative pathogen of hand, foot, and mouth disease (HFMD) in children. The epidemic of HFMD has been a public health problem in Asia-Pacific region for decades, and no vaccine and effective antiviral medicine
Externí odkaz:
https://doaj.org/article/723ddc80504743a4a44905f654c2ce6b
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2585 (2008)
BACKGROUND: Protein ubiquitination and/or degradation by the ubiquitin/proteasome system (UPS) have been recognized as critical mechanisms in the regulation of numerous essential cellular functions. The importance of the UPS in viral pathogenesis has
Externí odkaz:
https://doaj.org/article/737355bd337644fd9ad839d7f474ff28
Autor:
Lexun Lin, Yang Chen, Wenran Zhao, Xiaoning Si, Xiaoyan Zhong, Ying Qin, Zhaohua Zhong, Lei Tong, Xia Zhai, Yan Wang, Heng Wu, Shuo Wu, Bo Pan, Tianying Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 4, Iss 4, Pp 284-294 (2014)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Human enterovirus 71 (EV71) is the main causative pathogen of hand, foot, and mouth disease (HFMD) in children. The epidemic of HFMD has been a public health problem in Asia-Pacific region for decades, and no vaccine and effective antiviral medicine
Autor:
Zhaohua Zhong, Xiaoning Si, Shuo Wu, Wenran Zhao, Yelu Han, Xiaoyan Zhong, Xia Zhai, Lexun Lin, Bohai Yu, Tianying Wang, Ying Qin, Lei Tong, Zhiwei Guo, Yan Wang, Fengmin Zhang
Publikováno v:
Virology
The capsid proteins of some RNA viruses can translocate to the nucleus and interfere with cellular phenotypes. In this study we found that the VP1 capsid protein of coxsackievirus B3 (CVB3) was dominantly localized in the nucleus of the cells transfe
Autor:
Ali Bashashati, Aline Tabet, Kevin A. Janes, Xiaoning Si, Abbas Khalili, Raymond T. Ng, Brian W. Wong, David R. Marchant, Bruce M. McManus, Kevin Murphy, Honglin Luo, Farshid S. Garmaroudi
Publikováno v:
Proceedings of the National Academy of Sciences. 107:17053-17058
Signal transduction networks can be perturbed biochemically, genetically, and pharmacologically to unravel their functions. But at the systems level, it is not clear how such perturbations are best implemented to extract molecular mechanisms that und
Publikováno v:
Journal of Virology
Recent studies suggest a possible takeover of host antimicrobial autophagy machinery by positive-stranded RNA viruses to facilitate their own replication. In the present study, we investigated the role of autophagy in coxsackievirus replication. Coxs
Autor:
Guang Gao, Jerry Wong, Bruce M. McManus, Caroline Cheung, Honglin Luo, Jingchun Zhang, Xiaoning Si
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 295:H401-H408
Coxsackievirus B3 (CVB3) is one of the most prevalent pathogens of viral myocarditis, which may persist chronically and progress to dilated cardiomyopathy. We previously demonstrated a critical role of the ubiquitin-proteasome system (UPS) in the reg
Autor:
Shirley C. Chen, Daryoush Ekhterae, David J. Granville, Jingchun Zhang, Honglin Luo, Arwen L. Hunter, Brian W. Wong, Xiaoning Si
Publikováno v:
FEBS Letters. 581:879-884
Apoptosis repressor with caspase recruitment domain (ARC), an anti-apoptotic protein, is highly expressed in differentiated heart and skeletal muscle. Apoptosis and differentiation share numerous common pathways; therefore, we examined the impact of
Autor:
Zhen Liu, Travis Lim, Brian W. Wong, Bruce M. McManus, Dexin Qiu, Decheng Yang, Xiaoning Si, Ji Yuan, Honglin Luo
Publikováno v:
Anti-Infective Agents in Medicinal Chemistry. 5:367-377
Autor:
Agripina Suarez, Shoukat Dedhar, Ansel P Amaral, Xiaoning Si, Maziar Rahmani, Bruce M. McManus, Mitra Esfandiarei
Publikováno v:
Circulation Research. 99:354-361
Viral myocarditis is a major cause of sudden cardiac death in children and young adults. Among viruses, coxsackievirus B3 (CVB3) is the most common agent for myocarditis. Recently, more consideration has been given to the role of signaling pathways i