Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Xiaonan H. Wang"'
Autor:
Ying Huang, Bin Wang, Faten Hassounah, S. Russ Price, Janet Klein, Tamer M.A. Mohamed, Yanhua Wang, Jeanie Park, Hui Cai, Xuemei Zhang, Xiaonan H. Wang
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 126-141 (2023)
Abstract Background Muscle wasting is a common complication of chronic kidney disease (CKD) that is associated with higher mortality. Although the mechanisms of myofibre loss in CKD has been widely studied, the contribution of muscle precursor cell (
Externí odkaz:
https://doaj.org/article/5327ce09ea9242c2af18493a95b47f85
Autor:
Bin Wang, MD, PhD, Ze-Mu Wang, MD, PhD, Jia-Ling Ji, MD, Weihua Gan, PhD, Aiqing Zhang, PhD, Hao-Jie Shi, MD, Hao Wang, PhD, Linli Lv, MD, Zuolin Li, MD, Taotao Tang, MD, Jie Du, PhD, Xiaonan H. Wang, MD, Bi-Cheng Liu, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 5, Iss 2, Pp 148-166 (2020)
Summary: miR-155 was synthesized and loaded into exosomes in increased infiltration of macrophages in a uremic heart. The released exosomal fusion with the plasma membrane leads to the release of miR-155 into the cytosol and translational repression
Externí odkaz:
https://doaj.org/article/bc166a72caf641d6a26272b0a036cba5
Autor:
Ying Huang, Manshu Yu, Akihiro Kuma, Janet D. Klein, Yanhua Wang, Faten Hassounah, Hui Cai, Xiaonan H. Wang
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
BackgroundOur previous study found that acupuncture with low frequency electrical stimulation (Acu/LFES) prevents muscle atrophy by attenuation of protein degradation in mice. The current study examines the impact of Acu/LFES on protein synthesis.Met
Externí odkaz:
https://doaj.org/article/eeea631979de4a059571a9ef153434cd
Autor:
Ye Bi, Chunmei Li, Yiqian Zhang, Yunman Wang, Shan Chen, Qiang Yue, Robert S. Hoover, Xiaonan H. Wang, Eric Delpire, Douglas C. Eaton, Jieqiu Zhuang, Hui Cai
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
SPS1-related proline/alanine-rich kinase (SPAK) plays important roles in regulating the function of numerous ion channels and transporters. With-no-lysine (WNK) kinase phosphorylates SPAK kinase to active the SPAK signaling pathway. Our previous stud
Externí odkaz:
https://doaj.org/article/b156aa3b648949bb905467aea938a42b
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 9, Iss 4, Pp 755-770 (2018)
Abstract Background The treatment of muscle wasting is accompanied by benefits in other organs, possibly resulting from muscle–organ crosstalk. However, how the muscle communicates with these organs is less understood. Two microRNAs (miRs), miR‐2
Externí odkaz:
https://doaj.org/article/32309006cffc49758bd7191552ff0f8d
Autor:
Ying Huang, Bin Wang, Faten Hassounah, S. Russ Price, Janet Klein, Tamer M.A. Mohamed, Yanhua Wang, Jeanie Park, Hui Cai, Xuemei Zhang, Xiaonan H. Wang
Publikováno v:
Journal of cachexia, sarcopenia and muscleReferences.
Muscle wasting is a common complication of chronic kidney disease (CKD) that is associated with higher mortality. Although the mechanisms of myofibre loss in CKD has been widely studied, the contribution of muscle precursor cell (MPC) senescence rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269f1b4bd2bc0ded1ad3c9ed6d694b1d
https://pubmed.ncbi.nlm.nih.gov/36351875
https://pubmed.ncbi.nlm.nih.gov/36351875
Autor:
Robert S. Hoover, Jia Xiao, Xiaonan H. Wang, Xinxin Chen, Haian Fu, Hui Cai, Shan Chen, Zhizhi Zhuang, Xiuyan Feng, Douglas C. Eaton, Janet D. Klein
Publikováno v:
American Journal of Physiology-Renal Physiology. 319:F52-F62
14-3-3γ is a small protein regulating its target proteins through binding to phosphorylated serine/threonine residues. Sequence analysis of large-conductance Ca2+-activated K+ (BK) channels revealed a putative 14-3-3 binding site in the COOH-termina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a2e9edcd40d98ac36354001a50b5f3b
https://doi.org/10.1152/ajprenal.00584.2019
https://doi.org/10.1152/ajprenal.00584.2019
Autor:
Faten Hassounah, Janet D. Klein, Yajie Zhao, Xiaonan H. Wang, Wei He, Juan Wang, Aiqing Zhang, Bin Wang, Fuying Ma, Yan Liu, Haidong Wang
Publikováno v:
Hum Gene Ther
Renal fibrosis leads to end-stage renal disease, but antifibrotic drugs are difficult to develop. Chronic kidney disease often results in muscle wasting, and thereby increases morbidity and mortality. In this work, adeno-associated virus (AAV)-mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c6928eaaaeeca6703f04d51512c716
https://doi.org/10.1089/hum.2019.287
https://doi.org/10.1089/hum.2019.287
Autor:
Xiaonan H. Wang, Jingjie Xiao, Yan Yang, Ying-yan Wang, Yufang Xue, Yu-Chen Han, Qing Yin, Liuping Zhang, Li Zhang, Bi-Cheng Liu, Hong Liu, Xiaoliang Zhang, Ming-Ming Pan, Min Gao, Ri-Ning Tang, Yan Tu, Bin Wang
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Muscle wasting is associated with increased mortality and morbidity in chronic kidney disease (CKD) patients, especially in the haemodialysis (HD) population. Nevertheless, little is known regarding diaphragm dysfunction in HD patients. We conducted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75f8b8b0a6b1cd04bf90744444c57df
http://link.springer.com/article/10.1038/s41598-019-56035-4
http://link.springer.com/article/10.1038/s41598-019-56035-4
Publikováno v:
Nature reviews. Nephrology. 18(3)
Loss of muscle proteins is a deleterious consequence of chronic kidney disease (CKD) that causes a decrease in muscle strength and function, and can lead to a reduction in quality of life and increased risk of morbidity and mortality. The effectivene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1198c8fe8c6a995486d9558650a6494
https://pubmed.ncbi.nlm.nih.gov/34750550
https://pubmed.ncbi.nlm.nih.gov/34750550