Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Xiaona Chu"'
Autor:
Makayla S. Lancaster, Byungwook Kim, Emma H. Doud, Mason D. Tate, Ahmad D. Sharify, Hongyu Gao, Duojiao Chen, Ed Simpson, Patrick Gillespie, Xiaona Chu, Marcus J. Miller, Yue Wang, Yunlong Liu, Amber L. Mosley, Jungsu Kim, Brett H. Graham
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113241- (2023)
Summary: Lysine succinylation is a subtype of protein acylation associated with metabolic regulation of succinyl-CoA in the tricarboxylic acid cycle. Deficiency of succinyl-CoA synthetase (SCS), the tricarboxylic acid cycle enzyme catalyzing the inte
Externí odkaz:
https://doaj.org/article/3667fe089082442185bcfa19a5753f0c
Autor:
Megan L. Noonan, Pu Ni, Emmanuel Solis, Yamil G. Marambio, Rafiou Agoro, Xiaona Chu, Yue Wang, Hongyu Gao, Xiaoling Xuei, Erica L. Clinkenbeard, Guanglong Jiang, Sheng Liu, Steve Stegen, Geert Carmeliet, William R. Thompson, Yunlong Liu, Jun Wan, Kenneth E. White
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-15 (2023)
Abstract Osteocytes act within a hypoxic environment to control key steps in bone formation. FGF23, a critical phosphate-regulating hormone, is stimulated by low oxygen/iron in acute and chronic diseases, however the molecular mechanisms directing th
Externí odkaz:
https://doaj.org/article/f17e71dfa7c9425683b7aececc78f2ae
Autor:
Duojiao Chen, Sheng Liu, Xiaona Chu, Jill Reiter, Hongyu Gao, Patrick McGuire, Xuhong Yu, Xiaoling Xuei, Yichen Liu, Jun Wan, Fang Fang, Yunlong Liu, Yue Wang
Publikováno v:
Genes, Vol 14, Iss 10, p 1871 (2023)
Mesenchymal stem cells (MSC) are multipotent stem cells that can differentiate into multiple cell types, including osteoblasts, chondrocytes, and adipocytes. Osteoblast differentiation is reduced during osteoporosis development, resulting in reduced
Externí odkaz:
https://doaj.org/article/de2538b9dc1547f5a2d0e361ad94640e
Autor:
Yongyao Fu, Jocelyn Wang, Gayathri Panangipalli, Benjamin J. Ulrich, Byunghee Koh, Chengxian Xu, Rakshin Kharwadkar, Xiaona Chu, Yue Wang, Hongyu Gao, Wenting Wu, Jie Sun, Robert S. Tepper, Baohua Zhou, Sarath Chandra Janga, Kai Yang, Mark H. Kaplan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
BATF is a transcription factor that is needed for IL-9 production by T helper 9 cells. Here the authors show that STAT5 is needed at the Il9 locus to enable BATF to function in this manner and that this interaction can reprogram other T helper subset
Externí odkaz:
https://doaj.org/article/f65e400bd7f5452ca8fba9f15ba2dcc0
Autor:
Juli Liu, Sheng Liu, Hongyu Gao, Lei Han, Xiaona Chu, Yi Sheng, Weinian Shou, Yue Wang, Yunlong Liu, Jun Wan, Lei Yang
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-27 (2020)
Abstract Background Early human heart and brain development simultaneously occur during embryogenesis. Notably, in human newborns, congenital heart defects strongly associate with neurodevelopmental abnormalities, suggesting a common gene or complex
Externí odkaz:
https://doaj.org/article/9694bec7441b4d01b6359886c8eb31f9
Autor:
Siwen Xu, Weixing Feng, Zixiao Lu, Christina Y. Yu, Wei Shao, Harikrishna Nakshatri, Jill L. Reiter, Hongyu Gao, Xiaona Chu, Yue Wang, Yunlong Liu
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Expression quantitative trait loci (eQTL) analysis is useful for identifying genetic variants correlated with gene expression, however, it cannot distinguish between causal and nearby non-functional variants. Because the majority of disease-associate
Externí odkaz:
https://doaj.org/article/5ea15eeabf374f2281451f7093e2ef5a
Autor:
Xiaona Chu, Yue Wang, Harikrishna Nakshatri, Taylor M. Parker, Yunlong Liu, Duojiao Chen, Poornima Bhat-Nakshatri
Publikováno v:
Oncogene. 40:1332-1346
Chromatin accessibility is central to basal and inducible gene expression. Through ATAC-seq experiments in estrogen receptor-positive (ER+) breast cancer cell line MCF-7 and integration with multi-omics data, we found estradiol (E2) induced chromatin
Autor:
Makayla Suzanne Anderson, Emma H. Doud, Hongyu Gao, Duojiao Chen, Edward Simpson, Patrick Joseph Gillespie, Xiaona Chu, Marcus James Miller, Yue Wang, Yunlong Liu, Amber L. Mosley, Brett H. Graham
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
International Journal of Heat and Mass Transfer. 136:877-887
Interfacial oscillation associated with direct contact condensation of steam jet in water pipe flow is of high significance for industrial processes. In this paper, experimental study is conducted to reveal the mechanisms of the interfacial oscillati
Publikováno v:
Stem Cells Dev
Bone marrow-derived mesenchymal stem cells (MSCs) improve cardiac function after ischemia/reperfusion injury, in part, due to the release of cytoprotective paracrine factors. Toll-like receptor 4 (TLR4) is expressed in MSCs and regulates the expressi