Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Xiaomin Ling"'
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Renal ischemia‒reperfusion injury (IRI) is one of the main causes of acute kidney injury (AKI), which is a potentially life-threatening condition with a high mortality rate. IRI is a complex process involving multiple underlying mechanisms
Externí odkaz:
https://doaj.org/article/4989e993d30a4ba3967500b408a1638a
Autor:
Ying Yu, Chenning Li, Shuainan Zhu, Lin Jin, Yan Hu, Xiaomin Ling, Changhong Miao, Kefang Guo
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-18 (2023)
Abstract Acute kidney injury (AKI) is a common and serious complication of cardiac surgery and is associated with increased mortality and morbidity, accompanied by a substantial economic burden. The pathogenesis of cardiac surgery-associated acute ki
Externí odkaz:
https://doaj.org/article/3296126251fa4858a34846e252a5c91e
Autor:
Yunqian Qiao, Yangmin Qiu, Jie Ding, Nana Luo, Hao Wang, Xiaomin Ling, Jiya Sun, Zhihai Wu, Yisen Wang, Yanpeng Liu, Feifei Guo, Ta Sun, Wanwan Shen, Min Zhang, Dongdong Wu, Bingliang Chen, Wei Xu, Xuan Wang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The toxicity arising from generalised stimulation of T cells restricts applicability of CD137 agonists in cancer immune therapy. Here authors show that a bispecific antibody blocking PD-1 while activating CD137 efficiently restricts T cell activation
Externí odkaz:
https://doaj.org/article/5a74607a784c4173b05f771b90d4abb5
Autor:
Shuainan Zhu, Ying Yu, Yun Ren, Liying Xu, Huilin Wang, Xiaomin Ling, Lin Jin, Yan Hu, Hao Zhang, Changhong Miao, Kefang Guo
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-9 (2021)
Abstract Delayed wound healing causes problems for many patients both physically and psychologically, contributing to pain, economic burden, loss of function, and even amputation. Although many factors affect the wound healing process, abnormally pro
Externí odkaz:
https://doaj.org/article/f3abf692771e401fb067c8c82d5f0c4d
Autor:
Jia Zou, Li Li, Peiyi Zheng, Wenhua Liang, Siyi Hu, Shuaixiang Zhou, Yanqun Wang, Jincun Zhao, Daopeng Yuan, Lu Liu, Dongdong Wu, Mengqiu Xu, Fangfang Zhang, Mengzhu Zhu, Zhihai Wu, Xiaochao Cao, Meng Ni, Xiaomin Ling, Yue Wu, Zhihui Kuang, Moyan Hu, Jianfeng Li, Xue Li, Xiling Guo, Tianmin Xu, Haiping Jiang, Changshou Gao, Michael Yu, Junjian Liu, Nanshan Zhong, Jianfeng Zhou, Jian-an Huang, Tengchuan Jin, Jianxing He
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 4 (2022)
Many SARS-CoV-2 neutralizing antibodies (nAbs) lose potency against variants of concern. In this study, we developed 2 strategies to produce mutation-resistant antibodies. First, a yeast library expressing mutant receptor binding domains (RBDs) of th
Externí odkaz:
https://doaj.org/article/15dfcbaeebd944d996e5d9acb246d39b
Upregulation of GLT-1 via PI3K/Akt Pathway Contributes to Neuroprotection Induced by Dexmedetomidine
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Perioperative ischemic stroke usually leads to neurological dysfunction caused by neuron death. During the ischemic condition, excitotoxity due to extracellular glutamate accumulation is a main mechanism of neuron damage. The clearance of glutamate m
Externí odkaz:
https://doaj.org/article/5af41129e2074ce1b28c23b14c912604
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Maternal sevoflurane exposure during pregnancy is associated with increased risk for behavioral deficits in offspring. Several studies indicated that neurogenesis abnormality may be responsible for the sevoflurane-induced neurotoxicity, but the concr
Externí odkaz:
https://doaj.org/article/a1794776222d4339957172cd20cb1bc1
Autor:
Dongdong Wu, Yanpeng Liu, Xuan Wang, Ta Sun, Zhihai Wu, Yangmin Qiu, Jie Ding, Nana Luo, Yisen Wang, Yunqian Qiao, Wei Xu, Jiya Sun, Xiaomin Ling, Hao Wang, Feifei Guo, Wanwan Shen, Min Zhang, Bingliang Chen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
Expression of the cell surface receptor CD137 has been shown to enhance anti-cancer T cell function via engagement with its natural ligand 4-1BBL. CD137 ligation with engineered ligands has emerged as a cancer immunotherapy strategy, yet clinical dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2470532a839f4f4270968d8f3a43279b
https://doaj.org/article/5a74607a784c4173b05f771b90d4abb5
https://doaj.org/article/5a74607a784c4173b05f771b90d4abb5
Publikováno v:
Annals of Palliative Medicine. 9:3932-3937
Intravenous patient-controlled analgesia (IV-PCA) is recommended for postoperative systemic analgesia by the American Pain Society. As there is no efficacy advantage and a higher probability of adverse events, routine basal infusion of opioids is not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a00193f6773c8acc11bdc54472ca683
https://doi.org/10.21037/apm-20-1939
https://doi.org/10.21037/apm-20-1939
Publikováno v:
Gland Surg
Background In this retrospective study, we evaluated the effect of two approaches of robotic-assisted laparoscopic radical prostatectomy (RALP). The first approach was pneumoperitoneum via transperitoneal (TP-RALP), and the second approach was extrap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22dca44803bc6542a4a9b6f6d3535b4
https://doi.org/10.21037/gs-20-533
https://doi.org/10.21037/gs-20-533