Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Xiaomeng Cai"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 568-581 (2023)
The first poly(β-amino) esters (PβAEs) were synthesized more than 40 years ago. Since 2000, PβAEs have been found to have excellent biocompatibility and the capability of ferrying gene molecules. Moreover, the synthesis process of PβAEs is simple
Externí odkaz:
https://doaj.org/article/2cfd6595b84a4721ac32fe0a8972ce42
Autor:
Lifo Ruan, Jun Chen, Chuanchao Du, Huiru Lu, Jiayu Zhang, Xiaomeng Cai, Rui Dou, Wenchu Lin, Zhifang Chai, Guangjun Nie, Yi Hu
Publikováno v:
Bioactive Materials, Vol 13, Iss , Pp 191-199 (2022)
Reversal of cancer drug resistance remains a critical challenge in chemotherapy. Mitochondria-targeted drug delivery has been suggested to mitigate drug resistance in cancer. To overcome the intrinsic limitations in conventional mitochondrial targeti
Externí odkaz:
https://doaj.org/article/6eb2e378412c4e5cb5d1983263d9ff90
Publikováno v:
JCIS Open, Vol 9, Iss , Pp 100081- (2023)
The immunosuppressive tumor microenvironment often compromises chemotherapeutic efficacy. Tumor-associated macrophages (TAM) are a critical component of the tumor immune microenvironment, a large portion of which is in M2-polarization with immunosupp
Externí odkaz:
https://doaj.org/article/29d1e4f3ea6d4202bc2929f1c0671eaa
Autor:
Yuru Han, Baoyu Duan, Jing Wu, Yanjun Zheng, Yinchen Gu, Xiaomeng Cai, Changlian Lu, Xubo Wu, Yanfei Li, Xuefeng Gu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/af78116588ce48ecb263daf45704df9c
Autor:
Yuru Han, Baoyu Duan, Jing Wu, Yanjun Zheng, Yinchen Gu, Xiaomeng Cai, Changlian Lu, Xubo Wu, Yanfei Li, Xuefeng Gu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Myocardial infarction (MI) is one of the deadliest diseases in the world, and the changes at the molecular level after MI and the DNA methylation features are not clear. Understanding the molecular characteristics of the early stages of MI is of sign
Externí odkaz:
https://doaj.org/article/e4ccd02915ed43af91c5e8fd2e52a4b8
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1502 (2023)
Nucleic acid therapy can achieve lasting and even curative effects through gene augmentation, gene suppression, and genome editing. However, it is difficult for naked nucleic acid molecules to enter cells. As a result, the key to nucleic acid therapy
Externí odkaz:
https://doaj.org/article/3ebb6aaeafb840eea66cf603cfbc5b07
Publikováno v:
The Journal of Physical Chemistry C. 127:5576-5583
Publikováno v:
Journal of Biomaterials and Tissue Engineering. 13:287-293
BMSCs can effectively reduce the accumulation of extracellular matrix in renal tissues of rats with FSGS. This study intends to investigate the effect of BMSCs on extracellular matrix accumulation in renal tissues of rats with FSGS. 60 female mice ag
Publikováno v:
ACS Applied Bio Materials. 5:4103-4117
Mitochondrion is a multifunctional organelle in a cell, and it is one of the important targets of antitumor therapy. Conventional mitochondrial targeting strategies can hardly distinguish the mitochondria in cancer cells from those in normal cells, w
Autor:
Wenchu Lin, Zhifang Chai, Lifo Ruan, Guangjun Nie, Huiru Lu, Yi Hu, Jun Chen, Xiaomeng Cai, Rui Dou, Jia-yu Zhang, Chuanchao Du
Publikováno v:
Bioactive Materials, Vol 13, Iss, Pp 191-199 (2022)
Reversal of cancer drug resistance remains a critical challenge in chemotherapy. Mitochondria-targeted drug delivery has been suggested to mitigate drug resistance in cancer. To overcome the intrinsic limitations in conventional mitochondrial targeti