Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Xiaomeng, Ni"'
Autor:
Jin Wang, Ning Xue, Wenjia Pan, Ran Tu, Shixin Li, Yue Zhang, Yufeng Mao, Ye Liu, Haijiao Cheng, Yanmei Guo, Wei Yuan, Xiaomeng Ni, Meng Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Biosensors are powerful tools for detecting, real-time imaging, and quantifying molecules, but rapidly constructing diverse genetically encoded biosensors remains challenging. Here, we report a method to rapidly convert enzymes into genetica
Externí odkaz:
https://doaj.org/article/8acb33dc47f7483abb66589156955851
Autor:
Xinyang Liu, Jiao Liu, Zhemin Liu, Qianqian Qiao, Xiaomeng Ni, Jinxing Yang, Guannan Sun, Fanghe Li, Wenjuan Zhou, Xuan Guo, Jiuzhou Chen, Shiru Jia, Yu Zheng, Ping Zheng, Jibin Sun
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2024)
Allosteric regulation by pathway products plays a vital role in amino acid metabolism. Homoserine dehydrogenase (HSD), the key enzyme for the biosynthesis of various aspartate family amino acids, is subject to feedback inhibition by l-threonine and l
Externí odkaz:
https://doaj.org/article/494f5fb264df49a28c51892a9c96dad8
Autor:
Mengmeng Wang, Zhong Shi, Ning Gao, Yingyu Zhou, Xiaomeng Ni, Jiuzhou Chen, Jiao Liu, Wenjuan Zhou, Xuan Guo, Bo Xin, Yanbing Shen, Yu Wang, Ping Zheng, Jibin Sun
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Background Plant hemoglobin shows great potential as a food additive to circumvent the controversy of using animal materials. Microbial fermentation with engineered microorganisms is considered as a promising strategy for sustainable product
Externí odkaz:
https://doaj.org/article/c25e205cccfb4ee18c259b3a6dbb0447
Autor:
Xiaomei Zheng, Peng Du, Kaiyue Gao, Yimou Du, Timothy C. Cairns, Xiaomeng Ni, Meiling Chen, Wei Zhao, Xinrong Ma, Hongjiang Yang, Ping Zheng, Jibin Sun
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Aspergillus niger is the main industrial workhorse for global citric acid production. This fungus has complex sensing and signaling pathways to respond to environmental nutrient fluctuations. As the preferred primary carbon source, glucose also acts
Externí odkaz:
https://doaj.org/article/1414d2ac5776416891e67a6a7437bd89
Autor:
Jiao Liu, Moshi Liu, Tuo Shi, Guannan Sun, Ning Gao, Xiaojia Zhao, Xuan Guo, Xiaomeng Ni, Qianqian Yuan, Jinhui Feng, Zhemin Liu, Yanmei Guo, Jiuzhou Chen, Yu Wang, Ping Zheng, Jibin Sun
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Corynebacterium glutamicum is a major workhorse in industrial biomanufacturing of amino acids. Here, the authors employ CRISPR-assisted rational flux-tuning and CRISPRi screening of a L-proline exporter to covert a wild-type C. glutamicum to a hyperp
Externí odkaz:
https://doaj.org/article/8909610a7e924f37b99a9cdaf4ef0ff8
Autor:
Liwen Fan, Yu Wang, Jin Qian, Ning Gao, Zhihui Zhang, Xiaomeng Ni, Letian Sun, Qianqian Yuan, Ping Zheng, Jibin Sun
Publikováno v:
Microbial Biotechnology, Vol 14, Iss 4, Pp 1797-1808 (2021)
Summary Methanol is a promising feedstock for biomanufacturing of fuels and chemicals. Although efforts have been made to engineer platform microorganisms for methanol bioconversion, the substrate uptake and cell growth rates on methanol are still un
Externí odkaz:
https://doaj.org/article/072c42a700224864abea72d5dedce5c9
Autor:
Yu Wang, Haijiao Cheng, Yang Liu, Ye Liu, Xiao Wen, Kun Zhang, Xiaomeng Ni, Ning Gao, Liwen Fan, Zhihui Zhang, Jiao Liu, Jiuzhou Chen, Lixian Wang, Yanmei Guo, Ping Zheng, Meng Wang, Jibin Sun, Yanhe Ma
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
To obtain optimal yield and productivity in bioproduction, expression of pathway genes must be appropriately coordinated. Here, the authors report repurposing of base editors for simultaneous regulation of multiple gene expression and demonstrate its
Externí odkaz:
https://doaj.org/article/33779273c5a84abd9c7115b63093df48
Autor:
Jingwen Huang, Jiuzhou Chen, Yu Wang, Tuo Shi, Xiaomeng Ni, Wei Pu, Jiao Liu, Yingyu Zhou, Ningyun Cai, Shuangyan Han, Ping Zheng, Jibin Sun
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Corynebacterium glutamicum is an important workhorse for industrial production of diversiform bioproducts. Precise regulation of gene expression is crucial for metabolic balance and enhancing production of target molecules. Auto-inducible promoters,
Externí odkaz:
https://doaj.org/article/1826422e8de948dfaaf1e280f62f5fe0
Autor:
Xiaowei Wang, Qinggang Li, Cunmin Sun, Zhen Cai, Xiaomei Zheng, Xuan Guo, Xiaomeng Ni, Wenjuan Zhou, Yanmei Guo, Ping Zheng, Ning Chen, Jibin Sun, Yin Li, Yanhe Ma
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-13 (2019)
Abstract Background Late-stage fermentation broth contains high concentrations of target chemicals. Additionally, it contains various cellular metabolites which have leaked from lysed cells, which would exert multifactorial stress to industrial hyper
Externí odkaz:
https://doaj.org/article/ad1df27e2e594f9687f967543ad79416
Autor:
Yu Wang, Dongdong Zhao, Letian Sun, Jie Wang, Liwen Fan, Guimin Cheng, Zhihui Zhang, Xiaomeng Ni, Jinhui Feng, Meng Wang, Ping Zheng, Changhao Bi, Xueli Zhang, Jibin Sun
Publikováno v:
ACS Synthetic Biology. 11:3368-3378