Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Xiaomei NIU"'
Autor:
Andrey Ivanov, Xionghao Lin, Tatiana Ammosova, Andrey V. Ilatovskiy, Namita Kumari, Hatajai Lassiter, Nowah Afangbedji, Xiaomei Niu, Michael G. Petukhov, Sergei Nekhai
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-23 (2018)
Abstract Background HIV-1 transcription activator protein Tat is phosphorylated in vitro by CDK2 and DNA-PK on Ser-16 residue and by PKR on Tat Ser-46 residue. Here we analyzed Tat phosphorylation in cultured cells and its functionality. Results Mass
Externí odkaz:
https://doaj.org/article/5d0f09d884364e67bf1122b20246c298
Autor:
Namita Kumari, Tatiana Ammosova, Sharmin Diaz, Xionghao Lin, Xiaomei Niu, Andrey Ivanov, Marina Jerebtsova, Subhash Dhawan, Patricia Oneal, Sergei Nekhai
Publikováno v:
Blood Advances, Vol 1, Iss 3, Pp 170-183 (2016)
Abstract: The low incidence of HIV-1 infection in patients with sickle cell disease (SCD) and inhibition of HIV-1 replication in vitro under the conditions of low intracellular iron or heme treatment suggests a potential restriction of HIV-1 infectio
Externí odkaz:
https://doaj.org/article/2e2cc677196b44009c2cc815a6598f35
Publikováno v:
Viruses, Vol 12, Iss 2, p 204 (2020)
Human immunodeficiency virus (HIV)-infected individuals treated with anti-retroviral therapy often develop chronic non-infectious lung disease. To determine the mechanism of HIV-1-associated lung disease we evaluated the dynamics of lung leukocytes i
Externí odkaz:
https://doaj.org/article/23a98883977248138eb2f36899adbfbe
Autor:
Kuan-Teh Jeang, Sergei Nekhai, Xiaomei Niu, Gustavo Brito Alvim de Melo, Min Xu, Namita Kumari, Marina Jerebtsova
Publikováno v:
Biology, Vol 1, Iss 2, Pp 175-195 (2012)
A major challenge in studies of human diseases involving macrophages is low yield and heterogeneity of the primary cells and limited ability of these cells for transfections and genetic manipulations. To address this issue, we developed a simple and
Externí odkaz:
https://doaj.org/article/55219cbb2cb949a8a657da98285e4dc1
Autor:
Tatiana Ammosova, Kareem Washington, Jamie Rotimi, Namita Kumari, Kahli A. Smith, Xiaomei Niu, Marina Jerebtsova, Sergei Nekhai
Publikováno v:
Biology, Vol 5, Iss 4, p 49 (2016)
Protein phosphatase 1 (PP1), a cellular serine/threonine phosphatase, is targeted to cellular promoters by its major regulatory subunits, PP1 nuclear targeting subunit, nuclear inhibitor of PP1 (NIPP1) and RepoMan. PP1 is also targeted to RNA polymer
Externí odkaz:
https://doaj.org/article/d36a7093df21440487139a7703af6936
Autor:
Nikica Ljubas Tomasic, Lucie Piterkova, Chad Huff, Ernest Bilic, Donghoon Yoon, Galina Y. Miasnikova, Adelina I. Sergueeva, Xiaomei Niu, Sergei Nekhai, Victor Gordeuk, Josef T. Prchal
Publikováno v:
Haematologica, Vol 98, Iss 4 (2013)
Mutations of VHL (a negative regulator of hypoxia-inducible factors) have position-dependent distinct cancer phenotypes. Only two known inherited homozygous VHL mutations exist and they cause polycythemia: Chuvash R200W and Croatian H191D. We report
Externí odkaz:
https://doaj.org/article/adef9eac38274f7f83d77908abbec6d2
Autor:
Craig A. Sable, Zakari Y. Aliyu, Niti Dham, Mehdi Nouraie, Vandana Sachdev, Stanislav Sidenko, Galina Y. Miasnikova, Lydia A. Polyakova, Adelina I. Sergueeva, Daniel J. Okhotin, Vladimir Bushuev, Alan T. Remaley, Xiaomei Niu, Oswaldo L. Castro, Mark T. Gladwin, Gregory J. Kato, Josef T. Prchal, Victor R. Gordeuk
Publikováno v:
Haematologica, Vol 97, Iss 2 (2012)
Background Patients with Chuvash polycythemia, (homozygosity for the R200W mutation in the von Hippel Lindau gene (VHL)), have elevated levels of hypoxia inducible factors HIF-1 and HIF-2, often become iron-deficient secondary to phlebotomy, and have
Externí odkaz:
https://doaj.org/article/d9c537e8b8aa4aeb95cb987b860a82cf
Autor:
Galina Y. Miasnikova, Adelina I. Sergueeva, Mehdi Nouraie, Xiaomei Niu, Daniel J. Okhotin, Lydia A. Polyakova, Tomas Ganz, Josef T. Prchal, Victor R. Gordeuk
Publikováno v:
Haematologica, Vol 96, Iss 9 (2011)
The germ-line loss-of-function VHLR200W mutation is common in Chuvashia, Russia and occurs in other parts of the world. VHLR200W homozygotes have elevated hypoxia inducible factor (HIF)-1 and HIF-2 levels, increased hemoglobin concentration, propensi
Externí odkaz:
https://doaj.org/article/847a83f8fd88425ca906edf00b30042c
Autor:
Mehdi Nouraie, Kevin Cheng, Xiaomei Niu, Evadne Moore-King, Margaret F. Fadojutimi-Akinsi, Caterina P. Minniti, Craig Sable, Sohail Rana, Niti Dham, Andrew Campbell, Gregory Ensing, Gregory J. Kato, Mark T. Gladwin, Oswaldo L. Castro, Victor R. Gordeuk
Publikováno v:
Haematologica, Vol 96, Iss 8 (2011)
Background Bone changes are common in sickle cell disease, but the pathogenesis is not fully understood. Tartrate-resistant acid phosphatase (TRACP) type 5b is produced by bone-resorbing osteoclasts. In other forms of hemolytic anemia, increased iron
Externí odkaz:
https://doaj.org/article/38b5671823ab413bbbb46c59b858d75c
Autor:
Xiaomei Niu, Mehdi Nouraie, Andrew Campbell, Sohail Rana, Caterina P Minniti, Craig Sable, Deepika Darbari, Niti Dham, N Scott Reading, Josef T Prchal, Gregory J Kato, Mark T Gladwin, Oswaldo L Castro, Victor R Gordeuk
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7956 (2009)
BACKGROUND:Pulmonary hypertension and left ventricular diastolic dysfunction are complications of sickle cell disease. Pulmonary hypertension is associated with hemolysis and hypoxia, but other unidentified factors are likely involved in pathogenesis
Externí odkaz:
https://doaj.org/article/bd4d922f8353415780c2d3a51668442b