Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Xiaolu Zhao"'
Autor:
Yi Ding, Qiu-Bing Chen, Hui Xu, Dilare Adi, Yi-Wen Ding, Wen-Jun Luo, Wen-Zhuo Zhu, Jia-Chen Xu, Xiaolu Zhao, Xiong-Jie Shi, Jie Luo, Hao Yin, Xiao-Yi Lu
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 9, Pp 100626- (2024)
Atherosclerotic cardiovascular disease is closely correlated with elevated low density lipoprotein-cholesterol. In feeding state, glucose and insulin activate mammalian target of rapamycin 1 that phosphorylates the deubiquitylase ubiquitin-specific p
Externí odkaz:
https://doaj.org/article/0b8673db0a7b4527a95eddd6d7a264a6
Autor:
Fenfei Liang, Jiaxing Jin, Qiming Li, Jiangkai Duan, Ao Jiang, Xiaoqing Chen, Huichao Geng, Kai Wu, Fei Yu, Xiaolu Zhao, Yu Zhou, Deqing Hu, Liang Chen
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114368- (2024)
Summary: DOT1L mediates the methylation of histone H3 at lysine 79 and, in turn, the transcriptional activation or repression in a context-dependent manner, yet the regulatory mechanisms and functions of DOT1L/H3K79me remain to be fully explored. Fol
Externí odkaz:
https://doaj.org/article/b6dbf4ffdeee42ec82f202f02b2ef1b0
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 12, Pp 100465- (2023)
Accurate intracellular cholesterol traffic plays crucial roles. Niemann Pick type C (NPC) proteins NPC1 and NPC2, are two lysosomal cholesterol transporters that mediate the cholesterol exit from lysosomes. However, other proteins involved in this pr
Externí odkaz:
https://doaj.org/article/6077709dd9d34e4da493820344f2a460
Autor:
Jianjun Chen, Weiwen Xin, Weipeng Chen, Xiaolu Zhao, Yongchao Qian, Xiang-Yu Kong, Lei Jiang, Liping Wen
Publikováno v:
ACS Central Science, Vol 7, Iss 9, Pp 1486-1492 (2021)
Externí odkaz:
https://doaj.org/article/f0c21cf59a584e718d7ddf180824a764
Autor:
Shasha Li, Chenyang Lu, Yuan Zhang, Xiaolu Zhao, Kequan Lin, Xiufang Kong, David Fox, Lixiang Xue, Lichao Sun, Yi Liu, Fengbiao Mao
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104631- (2022)
Summary: Autoimmune diseases (ADs) are at a significantly higher risk of cancers with unclear mechanism. By searching GWAS catalog database and Medline, susceptible genes for five common ADs, including systemic lupus erythematosus (SLE), rheumatoid a
Externí odkaz:
https://doaj.org/article/2248d22ab6c9499b8556224e4abd7470
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1-15 (2021)
The novel coronavirus SARS-CoV-2 is damaging the world’s social and economic fabrics seriously. Effective drugs are urgently needed to decrease the high mortality rate of COVID-19 patients. Unfortunately, effective antiviral drugs or vaccines are c
Externí odkaz:
https://doaj.org/article/7689c3ac7ec94ebb9f06d51993558b03
Autor:
Weipeng Chen, Qianru Zhang, Yongchao Qian, Weiwen Xin, Dezhao Hao, Xiaolu Zhao, Congcong Zhu, Xiang-Yu Kong, Benzhuo Lu, Lei Jiang, Liping Wen
Publikováno v:
ACS Central Science, Vol 6, Iss 11, Pp 2097-2104 (2020)
Externí odkaz:
https://doaj.org/article/e8d15bf0ed824205bc95c1538f1b72af
Autor:
Jian Xiao, Yanni Xiong, Liu-Ting Yang, Ju-Qiong Wang, Zi-Mu Zhou, Le-Wei Dong, Xiong-Jie Shi, Xiaolu Zhao, Jie Luo, Bao-Liang Song
Publikováno v:
Protein & Cell, Vol 12, Iss 4, Pp 279-296 (2020)
Abstract Sterol-regulatory element binding proteins (SREBPs) are the key transcriptional regulators of lipid metabolism. The activation of SREBP requires translocation of the SREBP precursor from the endoplasmic reticulum to the Golgi, where it is se
Externí odkaz:
https://doaj.org/article/6678a80c4d5749f9810c3664c51c2ca2
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Background Periodontal ligament stem cells (PDLSCs) have many applications in the field of cytotherapy, tissue engineering, and regenerative medicine. However, the effect of age on the biological and immunological characteristics of PDLSCs r
Externí odkaz:
https://doaj.org/article/591e75721e2042d7b195d4ef39643277
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
The hydroxyproline-containing proteins (HCPs) among secretory and vacuolar proteins play important roles in growth and development of higher plants. Many hydroxyproline-rich glycoproteins (HRGPs), including Arabinogalactan proteins (AGPs), extensins
Externí odkaz:
https://doaj.org/article/75ac4c9b291b499291e24f28d2a61ec5