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Abstract 1546: ADCC enhanced anti-CD25 mAb (TST010) demonstrated antitumor activity via depleting Treg cells and increasing CD8+T/Treg ratio in preclinical tumor models

Autor: Di Sun, Huanhuan Guo, Hongjun Li, Xinlai Yao, Yiqing Xu, Shenjie Zhang, Shijie Zhou, Xiaoli Zi, Lisa Zheng, Yi Gu, Xueming Qian

Publikováno v: Cancer Research. 83:1546-1546

Regulatory T (Treg) cells are a distinctive lineage of CD4+ T cells as characterized by expression of FoxP3 and CD25 markers. Treg cells are involved in tumor development and progression by inhibiting antitumor immunity. Accumulation of Treg cells in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ce06818d04d350e491bbedce93bbe48
https://doi.org/10.1158/1538-7445.am2023-1546

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Abstract 5183: The preclinical characterization of TST001, a novel humanized anti-claudin18.2 mAb with enhanced binding affinity and anti-tumor activity

Autor: Timethy Liao, Francis Fan, Jerry Yang, Zhenzhi Yan, Xueming Qian, Huanhuan Guo, Zheng Dai, Hui Chai, Yi Gu, Xiaoli Zi, Fei Teng, Zhen Li, Lisa Zheng, Hongjun Li, Fei Xu, Xiwen Wu, Lei Shi, Xinlai Yao

Publikováno v: Cancer Research. 80:5183-5183

Claudin-18 isoform 2 (CLDN18.2) is a member of the human claudin family of tetraspan membrane proteins that are crucial structural and functional components of tight junctions. Unlike other family members, CLDN18.2 expression is strictly limited to d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d86d37b46f557d0fb855bfe8577857b3
https://doi.org/10.1158/1538-7445.am2020-5183

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Psychrotrophic Pseudomonas mandelii CBS-1 produces high levels of poly-β-hydroxybutyrate

Autor: Haofeng Gao, Yuji Jiang, Xiaoli Zi, Gao Yuan, Rongpeng Li, Xia Zhang, Nan Hu, Xinfeng Wang, Jingjing Yang

Publikováno v: SpringerPlus

A novel facultative psychrotroph (strain CBS-1), which accumulates poly-β-hydroxybutyrate (PHB), was isolated from soil samples taken from Changbai Mountain, China. Phylogenetic analysis based on 16S rRNA sequence data and Biolog analysis identified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286eb53814b645625d2b326608ea8b72
https://pubmed.ncbi.nlm.nih.gov/24010027

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Marinobacter hydrocarbonoclasticus NY-4, a novel denitrifying, moderately halophilic marine bacterium

Autor: Xia Zhang, Haofeng Gao, Xiaoli Zi, Nan Hu, Xinfeng Wang, Rongpeng Li

Publikováno v: SpringerPlus

The isolation and characterization of a novel halophilic denitrifying marine bacterium is described. The halophilic bacterium, designated as NY-4, was isolated from soil in Yancheng City, China, and identified as Marinobacter hydrocarbonoclasticus by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8b3b47958d76cf7710152e0efbc0ec

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